pharmacopeia

Mechanism of action

Sourced from openFDA

Mechanism-of-action classes: Corticosteroid Hormone Receptor Agonists; Glucocorticoid Receptor Agonists; Lipoxygenase Inhibitors.

Corticosteroid Hormone ReceptorGlucocorticoid ReceptorLipoxygenase

Indications

Sourced from openFDA
  • Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Contraindications

Sourced from openFDA
  • Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.contraindicated

Dosage & administration

Sourced from openFDA

Topical corticosteroids are generally applied to the affected area as a thin film from two to three times daily depending on the severity of the condition. Occlusive dressings may be a valuable therapeutic adjunct for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.

Adverse reactions

Sourced from openFDA

The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae and miliaria. To report SUSPECTED ADVERSE REACTIONS, contact Pharm-Olam at 1-866-511-6754 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Overdosage

Sourced from openFDA

Topically applied corticosteroids can be absorbed in sufficient amounts to produce systemic effects (see PRECAUTIONS ).

Approval history

Sourced from openFDA
  • May 31, 2002ANDAANDA076229Taro Pharm Inds
  • Nov 19, 2002ANDAANDA076096Genus
  • Mar 19, 2003ANDAANDA076367Taro Pharm Inds
  • May 15, 2003ANDAANDA076065Genus Lifesciences

FAERS reports

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Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
84 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
  1. 1Arthralgia1214%
  2. 2Pain In Extremity1214%
  3. 3Death1113%
  4. 4Pain911%
  5. 5Malaise89.5%
  6. 6Fatigue78.3%
  7. 7Insomnia78.3%
  8. 8Musculoskeletal Stiffness78.3%
  9. 9Pyrexia78.3%
  10. 10Anxiety67.1%
  11. 11Cough67.1%
  12. 12Feeling Hot67.1%
  13. 13Hypertension67.1%
  14. 14Psoriasis67.1%
  15. 15Renal Failure67.1%

Frequently asked questions

How does Amcinonide work?
Mechanism-of-action classes: Corticosteroid Hormone Receptor Agonists; Glucocorticoid Receptor Agonists; Lipoxygenase Inhibitors.
What is Amcinonide used for?
According to FDA labeling, Amcinonide carries indications including: Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
What class of drug is Amcinonide?
Amcinonide is classified as Corticosteroids, potent (group III), Corticosteroid, Corticosteroid Hormone Receptor Agonists, Glucocorticoid Receptor Agonists, Lipoxygenase Inhibitors, Antipruritic Activity, Decreased Immunologically Active Molecule Activity, Decreased Protein Synthesis, Vasoconstriction.
What are the contraindications for Amcinonide?
Amcinonide labeling lists contraindications including: Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.. Always consult the full prescribing information and a clinician.
Note. Data for amcinonide is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.

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