Ammonium
US-FDASourced from openFDA
GET
/api/v1/drug/ammoniumIndications
Sourced from openFDA- Low back pain and constipation*ICD-10: K59.00
Dosage & administration
Sourced from openFDAAdults and children: At the onset of symptoms, dissolve 5 pellets under the tongue 3 times a day until symptoms are relieved or as directed by a doctor.
Approval history
Sourced from openFDA- May 1, 2002ANDAANDA075774Padagis Israel
- Apr 10, 2003ANDAANDA075883Sun Pharma Canada
- May 28, 2004ANDAANDA076216Sun Pharma Canada
- Jun 23, 2004ANDAANDA075570Padagis Israel
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
3,208 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Nausea2718.4%
- 2Fatigue2568.0%
- 3Pain2568.0%
- 4Drug Ineffective2357.3%
- 5Headache2237.0%
- 6Off Label Use2086.5%
- 7Dyspnoea2076.5%
- 8Diarrhoea1996.2%
- 9Vomiting1795.6%
- 10Constipation1685.2%
- 11Condition Aggravated1665.2%
- 12Dizziness1564.9%
- 13Somnolence1504.7%
- 14Death1444.5%
- 15Arthralgia1424.4%
Literature
Recent PubMed references pinned to Ammonium as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Rapid bactericidal and nematicidal activity of a ternary quaternary ammonium formulation via membrane disruption in bacteria and cuticle damage in Bursaphelenchus xylophilus.Pesticide biochemistry and physiology · 2026 · Li M, Dou Y, Zheng Y, et al.PMID 42264723DOI 10.1016/j.pestbp.2026.107182
- Preliminary Evaluation of Gemini-Surfactant-Based Formulations for Antifungal Seed Treatment in Wheat.Molecules (Basel, Switzerland) · 2026 · Szczygieł T, Koziróg A, Otlewska A, et al.PMID 42197122DOI 10.3390/molecules31101568
- Preservation-to-Precision in Severe Early Childhood Caries: A Narrative Review of Silver Diamine Fluoride-When "Buying Time" Must Not Become "Selling Time".International journal of environmental research and public health · 2026 · Baghdadi ZDPMID 42196748DOI 10.3390/ijerph23050656
- Ion-Selective Electrodes for Ammonium and Nitrate Determination: Recent Advances, Trends and Perspectives.International journal of molecular sciences · 2026 · Morawska K, Wardak CPMID 42196407DOI 10.3390/ijms27104432
- Pilot-scale inoculum-free valorization of raw chicken feathers: ammonium recovery, keratinase production and community dynamics.World journal of microbiology & biotechnology · 2026 · de-Santos-Casado F, de la Fuente C, Martín-González D, et al.PMID 42184079DOI 10.1007/s11274-026-04976-0
- Hydroxylamine-accelerated cobalt redox cycling enables peroxymonosulfate activation for sustainable water remediation.Environmental research · 2026 · Liu B, Zou C, Hong X, et al.PMID 42162717DOI 10.1016/j.envres.2026.124797
- Silver diamine fluoride for dental caries: the good, the bad, and the ugly - insights from preclinical evidence.Archives of oral biology · 2026 · Ezhilarasan DPMID 42161187DOI 10.1016/j.archoralbio.2026.106631
- Synergistic cytotoxicity of benzalkonium chloride and didecyldimethylammonium chloride mixtures revealed by stress granule formation.Toxicology · 2026 · Kim MJ, Kim EM, Kim KK, et al.PMID 42155800DOI 10.1016/j.tox.2026.154504
Clinical trials
The 10 most recently updated of 797 ClinicalTrials.gov registrations naming Ammonium as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Citicoline in Youth Alcohol Use DisorderActive not recruiting · Phase 2 · Interventional · 56 enrolled · Medical University of South CarolinaNCT05870111updated 2026-06-12
- Oral Hyoscine vs Lidocaine-Prilocaine Spray vs Placebo for HSG Pain ReliefCompleted · Interventional · 102 enrolled · Cairo UniversityNCT07383571updated 2026-06-11
- Evaluation of the Clinical Impact of Adjunctive L-carnitine Therapy in Critically Ill Hepatic Patients Admitted to Intensive Care UnitNot yet recruiting · Phase 4 · Interventional · 58 enrolled · Beni-Suef UniversityNCT07642076updated 2026-06-11
- A Phase IIb Ensifentrine-glycopyrrolate Fixed-dose Combination Dose Ranging Study in Subjects With COPDRecruiting · Phase 2 · Interventional · 480 enrolled · Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USANCT07016412updated 2026-06-03
- Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or LymphomaActive not recruiting · Phase 3 · Interventional · 440 enrolled · Children's Oncology GroupNCT05602194updated 2026-06-02
- Pharmacological Reversal of Neuromuscular Blockade in Critically Ill PatientsRecruiting · Interventional · 30 enrolled · Seoul National University HospitalNCT05993390updated 2026-06-02
- Efficacy and Safety of "LMW - CL - HA - FACE/BODY" for the Augmentation of the CheeksCompleted · Interventional · 26 enrolled · Rose Pharma SANCT06915402updated 2026-05-29
- Imaging of Endometriosis With Total-body PET-CT (PET-Endo)Recruiting · Observational · 30 enrolled · University of EdinburghNCT07523997updated 2026-05-27
- Active Controlled Trial of CHF5993 Pressurized Metered-dose Inhaler ( pMDI) vs Symbicort®Turbuhaler® in Patients With Chronic Obstructive Pulmonary Disease ( COPD) (TRIVERSYTI)Completed · Phase 3 · Interventional · 708 enrolled · Chiesi Farmaceutici S.p.A.NCT03197818updated 2026-05-27
- Mechanisms of Diuretic Resistance in Heart Failure, Aim 3Recruiting · Phase 1 · Interventional · 50 enrolled · Yale UniversityNCT06209359updated 2026-05-22
Frequently asked questions
- What is Ammonium used for?
- According to FDA labeling, Ammonium carries indications including: Low back pain and constipation*. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
Note. Data for
ammonium is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.