Avobenzone

Mechanism-of-action class: Physiochemical Activity.

• Uses helps prevent sunburn if used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun

Directions apply liberally 15 minutes before sun exposure reapply at least every 2 hours use water resistant sunscreen if swimming or sweating Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: limit time in sun, especially from 10 a.m. - 2 p.m. wear long-sleeved shirts, pants, hats, and sunglasses children under 6 months: ask a doctor

For external use only Do not use on damaged or broken skin When using this product keep out of eyes. Rinse with water to remove. Stop use and ask a doctor if rash occurs Keep out of reach of children. If product is swallowed, get medical help or contact a Poison Control Center right away.

1. 1Drug Ineffective42818%
2. 2Dry Skin30713%
3. 3Erythema30212%
4. 4Acne30012%
5. 5Skin Burning Sensation29712%
6. 6Skin Irritation1917.9%
7. 7Skin Exfoliation1556.4%
8. 8Rash1546.4%
9. 9Pruritus1285.3%
10. 10Inappropriate Schedule Of Product Administration1184.9%
11. 11Hypersensitivity1084.5%
12. 12Condition Aggravated903.7%
13. 13Pain Of Skin803.3%
14. 14Overdose723.0%
15. 15Skin Cancer712.9%

The 5 most recently updated of 5 ClinicalTrials.gov registrations naming Avobenzone as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Singlet Oxygen Quantification After Skin Exposure to Ultraviolet A (UVA) Light
  Completed · Interventional · 17 enrolled · University of California, Davis
  NCT05865431updated 2025-04-27
• Assessing a Natural Product Plus Bioadhesive Nanoparticle (BNP) Sunscreen
  Completed · Phase 1 · Interventional · 30 enrolled · Yale University
  NCT05736224updated 2024-11-27
• Assessment of the Human Systemic Absorption of Sunscreen Ingredients
  Completed · Phase 1 · Interventional · 72 enrolled · Food and Drug Administration (FDA)
  NCT03582215updated 2020-04-21
• Determination of Sun Protection in Sunscreen Formulas (Study SR09-15)(P08236)(COMPLETED)
  Completed · Phase 3 · Interventional · 10 enrolled · Bayer
  NCT01001975updated 2015-03-11
• Ultraviolet and UV-Visible Light Photoprotection for the Treatment of Melasma
  Completed · Phase 4 · Interventional · 68 enrolled · Universidad Autonoma de San Luis Potosí
  NCT01695356updated 2014-12-02

Frequently asked questions

How does Avobenzone work?

Mechanism-of-action class: Physiochemical Activity.

What is Avobenzone used for?

According to FDA labeling, Avobenzone carries indications including: Uses helps prevent sunburn if used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Avobenzone?

Avobenzone is classified as Physiochemical Activity, Sunscreening Activity.