Overdose
104 drugs260,913 FAERS reportsMedDRA PT
GET
/api/v1/reaction/overdoseReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D062787
Accidental or deliberate use of a medication or street drug in excess of normal dosage.
Source: U.S. National Library of Medicine — MeSH (Drug Overdose)
Drugs reporting Overdose (104)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Polistirex47628%
- 2Hydromorphone23,02225%
- 3Hydrocodone23,11024%
- 4Fomepizole3720%
- 5Oxymorphone2,31020%
- 6Tapentadol5,88618%
- 7Zanamivir39516%
- 8Oxycodone58,86016%
- 9Hemp215%
- 10Hypromellose 2910114%
- 11Morphine25,37413%
- 12Sodium Nitrite713%
- 13Codeine2,53212%
- 14Helium612%
- 15Carbachol1711%
- 16Flotufolastat411%
- 17Tramadol3,88910%
- 18Papaverine1010%
- 19Lithium Chloride210%
- 20Meprobamate1219.5%
- 21Methadone4,0708.9%
- 22Meperidine7318.1%
- 23Adapalene13,2197.2%
- 24Salicylic Acid3,7777.2%
- 25Fentanyl8,1177.2%
- 26Chloramphenicol27.1%
- 27Naloxone2,5097.0%
- 28Nortriptyline3876.9%
- 29Triclabendazole36.8%
- 30Aminophylline1266.5%
- 31Activated Charcoal1626.2%
- 32Charcoal1626.2%
- 33Acetaminophen40,4956.1%
- 34Isopropyl Alcohol2,0276.1%
- 35Methylene Blue1035.9%
- 36Betaine895.8%
- 37Relebactam55.6%
- 38Kaolin35.6%
- 39Ethanolamine15.6%
- 40Ethanolamine Oleate15.6%
- 41Oleate15.6%
- 42Ethanol4155.2%
- 43Chlorpromazine3565.1%
- 44Quazepam155.0%
- 45Flumazenil414.9%
- 46Angiotensin Ii144.9%
- 47Methamphetamine504.7%
- 48Ketoprofen5764.5%
- 49Amoxapine204.2%
- 50Pentazocine24.2%
- 51Triazolam3544.1%
- 52Promethazine8874.0%
- 53Tranylcypromine444.0%
- 54Oxazepam8183.9%
- 55Disulfiram433.9%
- 56Carisoprodol7363.9%
- 57Isoproterenol163.9%
- 58Amisulpride2223.8%
- 59Ephedrine243.7%
- 60Flurazepam143.6%
- 61Sulfur5463.6%
- 62Galantamine1113.5%
- 63Diazepam4,1953.5%
- 64Clorazepate663.5%
- 65Dipotassium663.5%
- 66Temazepam1,2943.5%
- 67Lacosamide1,2353.4%
- 68Octisalate673.3%
- 69Minoxidil1,4453.3%
- 70Imipramine233.2%
- 71Acamprosate103.2%
- 72Olanzapine3,4293.2%
- 73Terlipressin93.1%
- 74Quetiapine5,8093.1%
- 75Valproic Acid9463.1%
- 76Octocrylene723.1%
- 77Clomipramine1343.0%
- 78Ziconotide733.0%
- 79Avobenzone723.0%
- 80Rotigotine4112.9%
- 81Estazolam542.8%
- 82Lithium1,1692.8%
- 83Nicotine1,6812.8%
- 84Dextromethorphan1,5282.7%
- 85Lithium Carbonate4522.6%
- 86Alprazolam5,2662.6%
- 87Fluvoxamine592.5%
- 88Ethiodized Oil302.4%
- 89Doxylamine1802.4%
- 90Valproate4732.4%
- 91Carbamazepine1,5282.3%
- 92Molnupiravir1172.3%
- 93Ceftolozane212.2%
- 94Pentobarbital22.2%
- 95Gallium92.1%
- 96Gozetotide92.1%
- 97Sapropterin1211.9%
- 98Mecasermin151.9%
- 99Fosphenytoin451.8%
- 100Bupivacaine2951.8%
- 101Suvorexant1931.5%
- 102Benzoyl Peroxide502—
- 103Brivaracetam452—
- 104Benzene1—
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
- Toxicity To Various Agents59 shared · 0.30
- Drug Abuse34 shared · 0.27
- Completed Suicide24 shared · 0.17
- Suicide Attempt21 shared · 0.16
- Drug Dependence19 shared · 0.16
- Intentional Overdose17 shared · 0.15
- Somnolence38 shared · 0.12
- Drug Interaction42 shared · 0.11
- Confusional State24 shared · 0.10
- Cardiac Arrest18 shared · 0.10
Literature
Recent PubMed references pinned to Drug Overdose as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Temporal Patterns of Alcohol- and Drug-Related Overdoses During the COVID-19 Pandemic: A National EMS-Based Study by Age and Gender in Israel.International journal of environmental research and public health · 2026 · Khalemsky A, Abramowitz MZ, Sonkin R, et al.PMID 42196712DOI 10.3390/ijerph23050619
- Ready, willing, and able: understanding opioid overdose preparedness among college students in the southwestern United States.Frontiers in public health · 2026 · Samora J, Lovett K, McCormick K, et al.PMID 42163910DOI 10.3389/fpubh.2026.1837454
- Leveraging near-peer teaching: the impact of cognitive and social congruence on naloxone training.Medical education online · 2026 · Polcyn J, VanBrackle R Jr, Zink N, et al.PMID 42157464DOI 10.1080/10872981.2026.2676337
- A community-based systematic review of economic evaluations of overdose prevention sites for people who use drugs: a study protocol.Substance abuse treatment, prevention, and policy · 2026 · Jozaghi E, Vancouver Area Network of Drug UsersPMID 42157163DOI 10.1186/s13011-025-00668-4
- Recurrent Seizure Induced an Overdose of Bupropion Hydrochloride Sustained-Release Tablets in an<br /> Adolescent: A Management Analysis.Journal of the College of Physicians and Surgeons--Pakistan : JCPSP · 2026 · Shi Y, Ruan P, Chen H, et al.PMID 42152219DOI 10.29271/jcpsp.2026.05.694
- Evaluation of continuous renal replacement therapy efficacy in severe caffeine intoxication: concentration-dependent variation in caffeine clearance.CEN case reports · 2026 · Takeda S, Chiba H, Yamazaki T, et al.PMID 42118481DOI 10.1007/s13730-026-01127-0
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.