Bacitracin
/api/v1/drug/bacitracinMechanism of action
Sourced from openFDAMechanism-of-action classes: Cell Membrane Fusion Complex Interactions; Enzyme Interactions.
Indications
Sourced from openFDA- Uses first aid to help prevent infection in: • minor cuts • scrapes • burns
Dosage & administration
Sourced from openFDADirections • clean the affected area • apply a small amount of this product (an amount equal to the surface area of the tip of a finger) on the area 1 to 3 times daily • may be covered with a sterile bandage
Warnings & precautions
Sourced from openFDAFor external use only Do not use • in the eyes • over large areas of the body • if you are allergic to any of the ingredients Ask a doctor before use if you have • deep or puncture wounds • animal bites • serious burns Stop use and ask a doctor if • you need to use longer than 1 week • condition persists or gets worse • rash or other allergic reaction develops Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
Approval history
Sourced from openFDA- Jan 26, 1995ANDAANDA064046Bausch And Lomb Inc
- Oct 30, 1995ANDAANDA064064Bausch And Lomb Inc
- Oct 30, 1995ANDAANDA064068Bausch And Lomb Inc
FAERS reports
- 1Drug Hypersensitivity3959.0%
- 2Drug Ineffective2696.2%
- 3Pain2365.4%
- 4Nausea2325.3%
- 5Dyspnoea2195.0%
- 6Diarrhoea2134.9%
- 7Fatigue2044.7%
- 8Rash2024.6%
- 9Off Label Use1723.9%
- 10Headache1633.7%
- 11Dizziness1623.7%
- 12Anxiety1563.6%
- 13Pyrexia1563.6%
- 14Vomiting1543.5%
- 15Pneumonia1473.4%
Literature
Recent PubMed references pinned to Bacitracin as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Antibiotic Repurposing: Conjugation of the Gram-Positive Only Peptide Antibiotic Bacitracin to a Bis-Catechol Siderophore Mimetic Imparts Potent Activity against Multi-Drug Resistant Acinetobacter baumannii.ACS infectious diseases · 2026 · Liu R, Miller PA, Miller MJ, et al.PMID 41875433DOI 10.1021/acsinfecdis.5c00943
- Green synthesis of a bacitracin@Ag-CeO(2) nanocomposite@hydrogel for dual antibiofilm and anti-inflammatory therapy against MRSA wound infections.Journal of materials chemistry. B · 2026 · Krishnamoorthi R, Hsiao CY, Chou YP, et al.PMID 41846420DOI 10.1039/d5tb02286j
- Paenitracins, a novel family of bacitracin-type nonribosomal peptide antibiotics produced by plant-associated Paenibacillus species.mSystems · 2026 · Machushynets NV, Elsayed SS, Du C, et al.PMID 41700860DOI 10.1128/msystems.01496-25
- Antimicrobial Functionalized Mesoporous Silica FDU-12 Loaded with Bacitracin.Molecules (Basel, Switzerland) · 2026 · Vasile DA, Motelica L, Mîrț LA, et al.PMID 41599388DOI 10.3390/molecules31020340
- Methanogenesis inhibition by bacitracin via modulating rumen microbial composition as demonstrated in in vitro assays.Journal of dairy science · 2026 · Zhang Z, Qing C, Zhang J, et al.PMID 41482041DOI 10.3168/jds.2025-27320
- Nature of bacitracin resistance in Staphylococcus aureus.Antimicrobial agents and chemotherapy · 2025 · Mohamad M, Hurst MM, Elkrewi E, et al.PMID 41186227DOI 10.1128/aac.00875-25
- Bioengineered nanocomposite bacitracin zinc-loaded chitosan microspheres containing keratin/gelatine films for wound healing.Journal of drug targeting · 2026 · Shetty P, Koland M, Saoji SD, et al.PMID 40884210DOI 10.1080/1061186X.2025.2554758
- A novel selective medium Sucrose-Bacitracin agar 10 for accurate isolation and identification of Streptococcus mutans.BMC oral health · 2025 · Fang Y, Ma Q, Zhao W, et al.PMID 40819078DOI 10.1186/s12903-025-06675-y
Clinical trials
The 10 most recently updated of 52 ClinicalTrials.gov registrations naming Bacitracin as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Impaired Risk Awareness During Intoxication in DUI OffendersCompleted · Interventional · 112 enrolled · Mark FillmoreNCT05247788updated 2026-05-12
- Multi-omics Dissection of Gut Microbiome Engraftment During FMTNot yet recruiting · Interventional · 90 enrolled · Catholic University of the Sacred HeartNCT06992453updated 2026-04-28
- Sebum Metabolomics and Lipidomics for Clinical ApplicationsNot yet recruiting · Interventional · 200 enrolled · National Taiwan University HospitalNCT07549828updated 2026-04-24
- Nailbed Repair for Patients With Nailbed InjuriesNot yet recruiting · Interventional · 100 enrolled · Stanford UniversityNCT07388823updated 2026-04-02
- Vancomycin Powder and Dilute Povidone Iodine Lavage for Infection Prophylaxis in High Risk Total Joint ArthroplastyCompleted · Phase 1 · Interventional · 2,129 enrolled · NYU Langone HealthNCT04075526updated 2026-02-17
- The Use of Medical Grade Honey in the Prevention of Bone Anchored Hearing Aid Associated Skin BreakdownCompleted · Phase 4 · Interventional · 17 enrolled · Henry Ford Health SystemNCT03929224updated 2026-01-07
- Clinical Assessment of Protopic® Ointment in Deep Partial-Thickness BurnsRecruiting · Phase 1 · Interventional · 18 enrolled · Vanderbilt University Medical CenterNCT05856994updated 2025-10-20
- The Effects of Post-Operative Interventions on Surgical Site Occurrences in AWRRecruiting · Interventional · 300 enrolled · Ohio State UniversityNCT04906408updated 2025-03-27
- Comparison of Collagenase With Antibiotic Ointment of Minor Partial Thickness BurnsTerminated · Phase 4 · Interventional · 20 enrolled · University of Kansas Medical CenterNCT02673229updated 2024-07-10
- Processed Amniotic Fluid (pAF) for the Treatment of Chronic WoundsTerminated · Phase 1 · Phase 2 · Interventional · 1 enrolled · University of UtahNCT04438174updated 2024-06-07
Frequently asked questions
- How does Bacitracin work?
- Mechanism-of-action classes: Cell Membrane Fusion Complex Interactions; Enzyme Interactions.
- What is Bacitracin used for?
- According to FDA labeling, Bacitracin carries indications including: Uses first aid to help prevent infection in: • minor cuts • scrapes • burns. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Bacitracin?
- Bacitracin is classified as Antibiotics, Other antibacterials, Other antibiotics for topical use, Cell Membrane Fusion Complex Interactions, Enzyme Interactions, Decreased Cell Wall Synthesis & Repair.
- What are the brand names for Bacitracin?
- Bacitracin is marketed under brand names including Baciguent, Bactine Antibiotic, Cuadriderma, Lanabiotic, Mycitracin Plus Pain Reliever, Neo-Polycin, Neo-Polycin HC, Polycin.
bacitracin is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.