Drug Hypersensitivity

DefinitionNLM MeSH D004342

Immunologically mediated adverse reactions to medicinal substances used legally or illegally.

Source: U.S. National Library of Medicine — MeSH (Drug Hypersensitivity)

Drugs reporting Drug Hypersensitivity (185)

Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.

1. 1Cobalt1743%
2. 2Formaldehyde2639%
3. 3Taurolidine338%
4. 4Meperidine3,25736%
5. 5Ammonium Chloride8335%
6. 6Gold1,84129%
7. 7Epoetin Beta2,96127%
8. 8Methoxy Polyethylene Glycol-epoetin Beta2,96127%
9. 9Penicillin G1,25026%
10. 10Benzalkonium12626%
11. 11Opium325%
12. 12Lincomycin6723%
13. 13Ropivacaine52223%
14. 14Erythromycin4,14622%
15. 15Tolmetin3420%
16. 16Tubocurarine220%
17. 17Penicillamine17920%
18. 18Penicillin V46019%
19. 19Iodine1,43818%
20. 20Procaine1417%
21. 21Glucosamine217%
22. 22Nalbuphine3616%
23. 23Cefaclor24316%
24. 24Hemp215%
25. 25Piroxicam96515%
26. 26Aminophylline29615%
27. 27Bismuth Subgallate715%
28. 28Butorphanol4815%
29. 29Nickel8514%
30. 30Neomycin90014%
31. 31Cefadroxil26014%
32. 32Nabilone25613%
33. 33Sucrose1,19413%
34. 34Butamben413%
35. 35Iron Sucrose1,15412%
36. 36Diatrizoate6312%
37. 37Pyrilamine5012%
38. 38Titanium5012%
39. 39Sulfasalazine8,36411%
40. 40Fenoprofen510%
41. 41Moxifloxacin1,97810%
42. 42Leflunomide9,7109.4%
43. 43Cefprozil739.4%
44. 44Sulfacetamide669.1%
45. 45Nefazodone119.1%
46. 46Meradimate19.1%
47. 47Efinaconazole1739.0%
48. 48Bacitracin3959.0%
49. 49Povidone-iodine3689.0%
50. 50Codeine1,8439.0%
51. 51Tetracycline1628.8%
52. 52Auranofin188.8%
53. 53Minocycline1,3708.4%
54. 54Risedronate2,5088.2%
55. 55Clindamycin3,0488.2%
56. 56Potassium Gluconate28.0%
57. 57Hypromellose 220837.9%
58. 58Gentian Violet47.8%
59. 59Tocilizumab8,7617.8%
60. 60Nortriptyline4377.8%
61. 61Theophylline8857.3%
62. 62Chlorine57.2%
63. 63Oxaprozin616.9%
64. 64Clavulanate1,8136.8%
65. 65Morphine12,4536.6%
66. 66Hydroxychloroquine9,6396.5%
67. 67Ciprofloxacin6,1566.4%
68. 68Sulfadiazine2466.4%
69. 69Polymyxin B3066.4%
70. 70Abatacept8,4056.2%
71. 71Ampicillin6576.2%
72. 72Doxercalciferol106.1%
73. 73Celecoxib7,8376.1%
74. 74Lanolin275.9%
75. 75Benzylpenicilloyl Polylysine25.9%
76. 76Diflunisal475.9%
77. 77Ketorolac3275.8%
78. 78Tramadol2,1845.8%
79. 79Enalaprilat145.7%
80. 80Castor Oil105.6%
81. 81Doxycycline3,7665.5%
82. 82Amoxicillin5,4515.5%
83. 83Orphenadrine405.4%
84. 84Anakinra8665.4%
85. 85Afamelanotide15.3%
86. 86Povidone4235.3%
87. 87Ergotamine185.2%
88. 88Citric Acid1175.1%
89. 89Azithromycin2,9645.1%
90. 90Nitrofurantoin1,2485.1%
91. 91Hydrocortisone6,0795.0%
92. 92Dicloxacillin94.9%
93. 93Ketoprofen6244.9%
94. 94Tromethamine3524.9%
95. 95Streptomycin564.9%
96. 96Metronidazole3,1394.9%
97. 97Tetracaine284.6%
98. 98Heparin6254.5%
99. 99Rituximab9,6364.5%
100. 100Trimethobenzamide624.4%
101. 101Influenza B Virus154.3%
102. 102Calcitriol8494.3%
103. 103Milnacipran2534.3%
104. 104Ammonia44.2%
105. 105Niacin5004.1%
106. 106Indomethacin5314.1%
107. 107Salsalate384.1%
108. 108Methotrexate19,5264.0%
109. 109Eugenol14.0%
110. 110Sulfamethoxazole3,3054.0%
111. 111Vitamin A2794.0%
112. 112Tea Tree Oil73.9%
113. 113Sulindac923.8%
114. 114Trimethoprim3,5993.8%
115. 115Misoprostol6223.8%
116. 116Phenazopyridine1433.8%
117. 117Azathioprine3,2463.7%
118. 118Naproxen5,9833.7%
119. 119Silver Sulfadiazine813.6%
120. 120Omalizumab2,9153.5%
121. 121Cephalexin7443.5%
122. 122Desipramine493.5%
123. 123Griseofulvin103.5%
124. 124Benzethonium73.5%
125. 125Titanium Dioxide123.4%
126. 126Fluorescein313.4%
127. 127Phenytoin1,3543.4%
128. 128Talc923.3%
129. 129Benzyl Alcohol43.3%
130. 130Lotilaner833.3%
131. 131Tropicamide533.3%
132. 132Droperidol523.3%
133. 133Alcaftadine293.3%
134. 134Silver1043.2%
135. 135Hydrochloric Acid73.2%
136. 136Hydromorphone2,9103.2%
137. 137Flurbiprofen483.1%
138. 138Progesterone6943.1%
139. 139Cefdinir2303.1%
140. 140Promethazine6843.1%
141. 141Cefuroxime4693.0%
142. 142Ibuprofen8,4653.0%
143. 143Levofloxacin1,7733.0%
144. 144Nafcillin273.0%
145. 145Quinine2643.0%
146. 146Metaxalone962.9%
147. 147Gemfibrozil4362.9%
148. 148Nabumetone1832.9%
149. 149Hypochlorite72.8%
150. 150Tolnaftate392.8%
151. 151Gabapentin10,0752.8%
152. 152Barium Sulfate122.8%
153. 153Pregabalin7,4252.8%
154. 154Cefazolin3262.8%
155. 155Crisaborole2602.7%
156. 156Palladium142.7%
157. 157Clarithromycin8512.5%
158. 158Etanercept14,9092.5%
159. 159Etodolac1472.5%
160. 160Octinoxate92.5%
161. 161Cefpodoxime232.4%
162. 162Atorvastatin5,9272.4%
163. 163Cefoxitin322.4%
164. 164Sumatriptan1,0672.4%
165. 165Difelikefalin92.3%
166. 166Asparaginase72.3%
167. 167Vancomycin1,4862.3%
168. 168Saxagliptin332.3%
169. 169Aztreonam1602.3%
170. 170Mepivacaine252.2%
171. 171Ceftriaxone7982.1%
172. 172Eletriptan1452.1%
173. 173Gatifloxacin362.1%
174. 174Lactobionate32.1%
175. 175Ketotifen1221.9%
176. 176Lebrikizumab261.9%
177. 177Icodextrin5561.8%
178. 178Florbetapir21.8%
179. 179Acoltremon451.7%
180. 180Ritlecitinib231.3%
181. 181Tioconazole181.2%
182. 182Polistirex201.2%
183. 183Boric Acid93—
184. 184Beta Carotene3—
185. 185Brilliant Blue G1—

Related reactions

Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.

• Rheumatoid Arthritis31 shared · 0.14
• Hypersensitivity48 shared · 0.14
• Rash117 shared · 0.13
• Drug Intolerance28 shared · 0.12
• Joint Swelling25 shared · 0.11
• Pain142 shared · 0.11
• Anxiety68 shared · 0.11
• Arthralgia91 shared · 0.10
• Chronic Kidney Disease34 shared · 0.10
• Dyspnoea140 shared · 0.10

Literature

Recent PubMed references pinned to Drug Hypersensitivity as a MeSH major topic. About the reaction term itself — not about any specific drug.

• [De-labeling of Penicillin Allergy in Hospitalized Patients: A Multidisciplinary Approach].
  Harefuah · 2026 · Sity Harel S, Karny Epstein N, Katzir M, et al.
  PMID 42200320
• Integrating Pharmacogenomics and Network Topology for Machine Learning Prediction of HLA-Associated Severe Cutaneous Adverse Drug Reactions.
  International journal of molecular sciences · 2026 · Ponduan T, Kunsombut A, Paklao T, et al.
  PMID 42196169DOI 10.3390/ijms27104187
• Comparing clinical practice guidelines on the prevention and management of chemotherapy-induced hand-foot syndrome.
  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026 · Sferrazza D, Wang N, Lustberg M, et al.
  PMID 42189295DOI 10.1007/s00520-026-10809-5
• DRESS'ed in Shock and Delay in Eosinophilia Resolution: Management Dilemmas in a Complex Case of Vancomycin-Induced DRESS Syndrome.
  The American journal of case reports · 2026 · Nwokeocha SO, Abduova L, Khatiwada D, et al.
  PMID 42175544DOI 10.12659/AJCR.952490
• Preventive and Therapeutic Interventions for Anticancer Drug-induced Dermatologic Toxicities: a Scoping Review.
  Current oncology reports · 2026 · Iimura Y, Kuroda S
  PMID 42151517DOI 10.1007/s11912-026-01797-0
• Exploring drug hypersensitivity in children with chronic spontaneous Urticaria: A comprehensive analysis using diagnostic tests.
  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026 · Gürbüz S, Kılavuz GÜ, Altintaş E, et al.
  PMID 42149737DOI 10.1111/pai.70381