Calcium Citrate
/api/v1/drug/calcium-citrateBoxed warning
Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. KEEP THIS PRODUCT OUT OF THE REACH OF CHILDREN. In case of accidental overdose, call a doctor or poison control center immediately.
Mechanism of action
Sourced from openFDAMechanism-of-action class: Electrolyte Activity.
Indications
Sourced from openFDA- CitraNatal Assure ® is a multivitamin/mineral prescription drug indicated for use in improving the nutritional status of women prior to conception, throughout pregnancy, and in the postnatal period for both lactating and nonlactating mothers.
Contraindications
Sourced from openFDA- This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.contraindicated
Dosage & administration
Sourced from openFDAOne tablet and one capsule daily or as directed by a physician.
Warnings & precautions
Sourced from openFDAIngestion of more than 3 grams of omega-3 fatty acids per day has been shown to have potential antithrombotic effects, including an increased bleeding time and INR. Administration of omega-3 fatty acids should be avoided in patients on anticoagulants and in those known to have an inherited or acquired bleeding diathesis.
Adverse reactions
Sourced from openFDAAllergic sensitization has been reported following both oral and parenteral administration of folic acid.
FAERS reports
- 1Maternal Exposure During Pregnancy414%
- 2Arthralgia310%
- 3Fall310%
- 4Nausea310%
- 5Pruritus310%
- 6Drug Ineffective26.9%
- 7Fatigue26.9%
- 8Headache26.9%
- 9Hypoaesthesia26.9%
- 10Injection Site Pain26.9%
- 11Insomnia26.9%
- 12Joint Swelling26.9%
- 13Pain In Extremity26.9%
- 14Abdominal Pain13.4%
- 15Abdominal Pain Upper13.4%
Literature
Recent PubMed references pinned to Calcium Citrate as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Measurement of precipitated calcium citrate in 24-hour urine samples is clinically useful for ruling out calcium oxalate urolithiasis.Science progress · 2026 · Tantasith C, Tubsaeng P, Boonkam K, et al.PMID 41940570DOI 10.1177/00368504251363660
- Effect of Calcium Citrate Versus Calcium Carbonate on Parathyroid Hormone Levels in Patients Undergoing Bariatric Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Obesity surgery · 2026 · Rahmani J, Baziar N, Malekpour Alamdari N, et al.PMID 41806228DOI 10.1007/s11695-026-08513-8
- Tricalcium Citrate Tetrahydrate TB as Filler in Direct Compression of Minitablets.AAPS PharmSciTech · 2026 · Hafels M, Mattusch A, Wagner KG, et al.PMID 41721144DOI 10.1208/s12249-026-03360-3
- Calcium citrate nanoparticles as a new frontier in metabolic acidosis treatment.Nanoscale · 2025 · Udomsinsirikul T, Anegkamol W, Thongsricome T, et al.PMID 41060681DOI 10.1039/d5nr01856k
- Octacalcium Phosphate/Calcium Citrate/Methacrylated Gelatin Composites: Optimization of Photo-Crosslinking Conditions and Osteogenic Potential Evaluation.International journal of molecular sciences · 2025 · Wang Y, Yokoi T, Shimabukuro M, et al.PMID 40725134DOI 10.3390/ijms26146889
- Calcium Supplement Combined with Dietary Supplement Kidtal Can Promote Longitudinal Growth of Long Bone in Calcium-Deficient Adolescent Rats.Nutrients · 2025 · Xie H, Zhang M, Zhou Z, et al.PMID 40573078DOI 10.3390/nu17121966
- Preparation and properties of chitosan/gelatin/supersaturated calcium citrate scaffolds crosslinked by dehydrogenation heat treatment method.International journal of biological macromolecules · 2025 · He W, Ma P, Zhang Z, et al.PMID 39938817DOI 10.1016/j.ijbiomac.2025.140844
- Comparison of calcium citrate and calcium carbonate absorption in patients with a Roux-en-Y gastric bypass, sleeve gastrectomy, and one-anastomosis gastric bypass: a double-blind, randomized cross-over trial.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2025 · Hany M, Wuyts S, Abouelnasr AA, et al.PMID 39603923DOI 10.1016/j.soard.2024.10.034
Clinical trials
The 10 most recently updated of 176 ClinicalTrials.gov registrations naming Calcium Citrate as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain AmyloidosisActive not recruiting · Phase 1 · Interventional · 24 enrolled · National Cancer Institute (NCI)NCT04847453updated 2026-06-11
- Potential Therapeutic Role of Effervescent Calcium-Magnesium Citrate in Chronic Kidney Disease Stage VActive not recruiting · Phase 2 · Phase 3 · Interventional · 269 enrolled · University of Texas Southwestern Medical CenterNCT03565913updated 2026-06-03
- Empiric Versus Selective Prevention Strategies for Kidney Stone DiseaseCompleted · Phase 4 · Interventional · 56 enrolled · Vanderbilt University Medical CenterNCT05365477updated 2026-06-03
- Nafamostat Mesylate Versus Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy in Sepsis-Associated Acute Kidney InjuryNot yet recruiting · Phase 4 · Interventional · 1,162 enrolled · Jianfeng XieNCT07518303updated 2026-06-03
- Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary StonesRecruiting · Phase 4 · Interventional · 25 enrolled · University of Texas Southwestern Medical CenterNCT06003348updated 2026-06-02
- Comparison of Citrate and Heparin Anticoagulation During Postdilution HemodiafiltrationNot yet recruiting · Interventional · 20 enrolled · University Medical Centre LjubljanaNCT07618858updated 2026-06-01
- Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Males (Drug Interaction Study and Preliminary Regimen-Finding Study)Completed · Phase 1 · Interventional · 84 enrolled · Tanabe Pharma CorporationNCT04481789updated 2026-05-22
- Testing the Addition of an Anti-Cancer Drug, Glofitamab, to the Usual Chemotherapy Treatment (Alternating R-CHOP/R-DHAP) for Previously Untreated Mantle Cell LymphomaNot yet recruiting · Phase 1 · Interventional · 16 enrolled · National Cancer Institute (NCI)NCT07444710updated 2026-05-13
- Personalized Two-stage Regional Citrate Anticoagulation for CRRT in Patients With Citrate Metabolism ImpairmentNot yet recruiting · Interventional · 142 enrolled · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityNCT07579663updated 2026-05-12
- Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic LeukemiaRecruiting · Phase 2 · Interventional · 80 enrolled · Mayo ClinicNCT03418038updated 2026-04-16
Frequently asked questions
- How does Calcium Citrate work?
- Mechanism-of-action class: Electrolyte Activity.
- What is Calcium Citrate used for?
- According to FDA labeling, Calcium Citrate carries indications including: CitraNatal Assure ® is a multivitamin/mineral prescription drug indicated for use in improving the nutritional status of women prior to conception, throughout pregnancy, and in the postnatal period for both lactating and nonlactating mothers.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Calcium Citrate?
- Calcium Citrate is classified as Calcium, Electrolyte Activity, Bone Resorption Alteration, Increased Renal PO4-- Excretion.
- What are the brand names for Calcium Citrate?
- Calcium Citrate is marketed under brand names including Calcet.
- What are the contraindications for Calcium Citrate?
- Calcium Citrate labeling lists contraindications including: This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.. Always consult the full prescribing information and a clinician.
calcium-citrate is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.