Castor Oil
/api/v1/drug/castor-oilIndications
Sourced from openFDA- Use For the temporary relief of occasional constipation. Bowel movement is generally produced in 6 to 12 hours.ICD-10: K59.00
Dosage & administration
Sourced from openFDADirections Preferably take on an empty stomach. May be taken with juice to improve taste. Adults and children 12 yrs. of age and older: 1 to 4 tablespoonfuls in a single daily dose or as directed by a doctor. Children 2 to under 12 yrs. of age: 1 to 3 tablespoonfuls in a single dose or as directed by a doctor. Children under 2 yrs. of age: Consult a doctor before use.
Warnings & precautions
Sourced from openFDAWarings Do not use when abdominal pain, nausea, or vomiting are present unless directed by a doctor.
FAERS reports
- 1Fatigue2313%
- 2Diarrhoea2212%
- 3Drug Ineffective2011%
- 4Nausea2011%
- 5Constipation169.0%
- 6Fall169.0%
- 7Asthenia147.9%
- 8Headache137.3%
- 9Off Label Use137.3%
- 10Vomiting126.7%
- 11Blood Pressure Increased116.2%
- 12Pain116.2%
- 13Anxiety105.6%
- 14Drug Hypersensitivity105.6%
- 15Dyspnoea105.6%
Literature
Recent PubMed references pinned to Castor Oil as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Development of an Optional Preparation Method for Synthesis of Branched Fatty Acid Esters of Hydroxy Fatty Acids by Castor Oil.Journal of agricultural and food chemistry · 2026 · Zhen C, Du M, Xu X, et al.PMID 42104940DOI 10.1021/acs.jafc.6c02530
- Castor oil-based waterborne polyurethane photodynamic antimicrobial films: Preparation and strawberry preservation application.Food research international (Ottawa, Ont.) · 2026 · Zhu Z, Liu L, Sha J, et al.PMID 41895946DOI 10.1016/j.foodres.2026.118865
- Castor oil/ZnO-loaded quaternized chitosan nanocomposite with multiple antimicrobials, anti-biofilm and pro-healing functions for advanced wound dressings.International journal of biological macromolecules · 2026 · Nabil Y, Atta AH, Abd Elwahab NH, et al.PMID 41876024DOI 10.1016/j.ijbiomac.2026.151610
- Development, optimization, and in vitro assessment of abuse-deterrent formulation.Journal of opioid management · 2026 · Bhola J, Borkhataria CPMID 41774071DOI 10.5055/jom.0973
- The hydroxyl content of biochar mediates the coating structure to dominate the release performance of castor oil-based polyurethane coated urea.Environmental research · 2026 · Li Z, Chen Y, Qin R, et al.PMID 41690362DOI 10.1016/j.envres.2026.124022
- Highly Sensitive Biosensor for the Detection of Cardiac Troponin I in Serum via Surface Plasmon Resonance on Polymeric Optical Fiber Functionalized with Castor Oil-Derived Molecularly Imprinted Nanoparticles.Biosensors · 2025 · Marinangeli A, Hatir PC, Yagci MB, et al.PMID 41590264DOI 10.3390/bios16010012
- Vanillic acid reverses castor oil-induced diarrhea in BALB/c mice through cholinergic and calcium channel blocking effects.Pakistan journal of pharmaceutical sciences · 2026 · Bashir D, Shah N, Jabbar Shah A, et al.PMID 41482797DOI 10.36721/PJPS.2026.39.1.FPS.13871.1
- A Consolidated Saccharification, Fermentation, and Transesterification Process (cSFT) Converting Castor Oil to Biodiesel with Cellulose-Derived Ethanol.International journal of molecular sciences · 2025 · Korkus Hamal E, Alfassi G, Rein DM, et al.PMID 41465329DOI 10.3390/ijms262411902
Clinical trials
The 10 most recently updated of 46 ClinicalTrials.gov registrations naming Castor Oil as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- CBD Knee Osteoarthritis StudyNot yet recruiting · Phase 2 · Interventional · 30 enrolled · University of TennesseeNCT07638189updated 2026-06-10
- Castor Oil Ingestion and Balloon Catheter for Labor Induction in NulliparousRecruiting · Interventional · 142 enrolled · Holy Family Hospital, Nazareth, IsraelNCT06325007updated 2026-04-13
- Castor Oil Ingestion and Balloon Catheter for Labor Induction in MultiparousRecruiting · Interventional · 216 enrolled · Holy Family Hospital, Nazareth, IsraelNCT06335017updated 2026-04-13
- Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy AdultsNot yet recruiting · Phase 1 · Interventional · 72 enrolled · Alcamena Stem Cell TherapeuticsNCT07363395updated 2026-01-23
- Trans Fatty Acids and Cardiovascular Risk FactorsCompleted · Interventional · 46 enrolled · Institut National de Recherche pour l'Agriculture, l'Alimentation et l'EnvironnementNCT00439582updated 2025-11-21
- Injectable DMAU for Male Contraception in Healthy Male Volunteers (CCN015)Completed · Phase 1 · Interventional · 106 enrolled · Kimberly MyerNCT02927210updated 2025-10-31
- Study of Spermatogenesis Suppression With DMAU Alone or With LNG Versus Placebo Alone in Normal MenCompleted · Phase 2 · Interventional · 92 enrolled · Premier ResearchNCT03455075updated 2025-10-30
- Effectiveness of Castor Oil in Preventing Formal Induction of Labour in a Tertiary InstitutionCompleted · Interventional · 100 enrolled · Assumpta Nnenna NwekeNCT06841939updated 2025-02-24
- A Study of Perturbation of Human Small Intestinal Colonic PermeabilityCompleted · Early phase 1 · Interventional · 24 enrolled · Mayo ClinicNCT06033222updated 2024-09-19
- The Effects of Topical Almond Oil and Tretinoin on Facial WrinklesRecruiting · Interventional · 90 enrolled · Integrative Skin Science and ResearchNCT06571721updated 2024-08-28
Frequently asked questions
- What is Castor Oil used for?
- According to FDA labeling, Castor Oil carries indications including: Use For the temporary relief of occasional constipation. Bowel movement is generally produced in 6 to 12 hours.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Castor Oil?
- Castor Oil is classified as Contact laxatives.
- What are the brand names for Castor Oil?
- Castor Oil is marketed under brand names including Optase, Venelex.
castor-oil is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.