Formaldehyde

Mechanism-of-action classes: Immunologic Factor Interactions; Unknown Cellular or Molecular Interaction.

• Fitful cough*ICD-10: R05.9

Adults and children: At the onset of symptoms, dissolve 5 pellets under the tongue 3 times a day until symptoms are relieved or as directed by a doctor.

1. 1Drug Hypersensitivity2639%
2. 2Fatigue1218%
3. 3Influenza1015%
4. 4Allergy To Chemicals913%
5. 5Infusion Related Reaction913%
6. 6Pharyngitis Streptococcal913%
7. 7Respiratory Rate Increased913%
8. 8Blood Test Abnormal812%
9. 9Joint Stiffness812%
10. 10Parathyroid Hyperplasia812%
11. 11Dyspnoea710%
12. 12Malaise69.0%
13. 13Off Label Use57.5%
14. 14Eczema Infected46.0%
15. 15Eczema Nummular46.0%

Recent PubMed references pinned to Formaldehyde as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Synergistic Mechanisms of Formaldehyde-Induced Radicals Enhancing Photothermal Catalytic Oxidation of Toluene.
  Environmental science & technology · 2026 · Wang H, Li S, Guo X, et al.
  PMID 42207956DOI 10.1021/acs.est.6c04237
• From spruce packaging waste to fluorescent carbon quantum dots/formaldehyde detection probe: performance and mechanism.
  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2026 · Li Y, Fang L, Gao S, et al.
  PMID 42143802DOI 10.1016/j.saa.2026.128070
• The formaldehyde dispute - Part A: acute and chronic inhalation toxicity and the evolution of scientific knowledge.
  Critical reviews in toxicology · 2026 · Siracusa J, Perry Q, Stevens M, et al.
  PMID 42101931DOI 10.1080/10408444.2026.2630665
• The formaldehyde dispute - Part B: scientific critique of EPA's formaldehyde occupational exposure values (OEVs) and proposed alternative occupational exposure limits (OELs).
  Critical reviews in toxicology · 2026 · Perry Q, Siracusa J, Stevens M, et al.
  PMID 42101930DOI 10.1080/10408444.2026.2630662
• Laser Capture Microdissection of Paraformaldehyde-Fixed Mouse Liver Tissue for RNA Analysis.
  Journal of visualized experiments : JoVE · 2026 · Zeng WL, Zhang MM, Zeng WJ, et al.
  PMID 42081494DOI 10.3791/69814
• Multivariate Assessment of Microbiological and Incubation Data from an Experimental Trial Evaluating Essential Oil-Based Sanitizers and Formaldehyde on Hatching Eggs.
  Pathogens (Basel, Switzerland) · 2026 · Dos Santos VM, Oliveira GDS, McManus C, et al.
  PMID 42075753DOI 10.3390/pathogens15040426
• Simple, Fast, and Highly Efficient One- or Two-Step Proteomic Preparation Enables Deep Profiling of Microgram-Level FF and FFPE Tissues.
  Analytical chemistry · 2026 · Wei C, Zhang Q, Fu C, et al.
  PMID 42046375DOI 10.1021/acs.analchem.5c07442
• Key Urinary Nutrients Affecting Formaldehyde-Induced Bacteriostatic Effect in Urinary Tract Infection Prophylaxis.
  Urology · 2026 · Ratevosyan R, Zimmern P, Reitzer L, et al.
  PMID 42025929DOI 10.1016/j.urology.2026.04.023

The 10 most recently updated of 281 ClinicalTrials.gov registrations naming Formaldehyde as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Percutaneous Biopsy After Neoadjuvant Chemotherapy.
  Not yet recruiting · Interventional · 100 enrolled · Instituto do Cancer do Estado de São Paulo
  NCT07644455updated 2026-06-12
• A Synthetic Lethality-Focused Algorithm to Identify Therapeutic Options in Advanced Metastatic Breast Cancer (SYNTHESIS-Breast)
  Suspended · Interventional · 175 enrolled · National Cancer Institute (NCI)
  NCT07067138updated 2026-06-04
• Immunogenicity and Safety of I-HAV in Healthy Thai Children and Adolescents Lacking Protective Antibody After L-HAV
  Active not recruiting · Phase 3 · Interventional · 36 enrolled · Chiang Mai University
  NCT06978621updated 2026-05-22
• Clinically Actionable Tumor-Associated Antigens in Prostate Cancer
  Active not recruiting · Observational · 1,600 enrolled · Peking University First Hospital
  NCT07597369updated 2026-05-19
• A Study to Evaluate the Performance of Confocal Microscopy to Detect Positive Margins During Radical Prostatectomy
  Recruiting · Interventional · 693 enrolled · University College, London
  NCT07541911updated 2026-05-18
• Frozen Section Examination of Sentinel Lymph Nodes in Breast Cancer
  Active not recruiting · Interventional · 142 enrolled · Izmir City Hospital
  NCT07591506updated 2026-05-15
• Histidine and Immunotherapy Response in Colorectal Cancer
  Not yet recruiting · Observational · 150 enrolled · Jing-yuan Fang, MD, Ph. D
  NCT07586293updated 2026-05-14
• Treating Patients With Melanoma and ALK Alterations With Ensartinib
  Active not recruiting · Phase 2 · Interventional · 18 enrolled · Memorial Sloan Kettering Cancer Center
  NCT03420508updated 2026-05-13
• Molecular Profiling Project
  Suspended · Observational · 500 enrolled · National Cancer Centre, Singapore
  NCT04025515updated 2026-05-12
• Correlation and Heterogeneity of the Immune Microenvironment and Histopathological Growth Patterns in Resectable Colorectal Cancer Liver Metastases
  Active not recruiting · Observational · 64 enrolled · Meng Qiu
  NCT07564908updated 2026-05-04

Frequently asked questions

How does Formaldehyde work?

Mechanism-of-action classes: Immunologic Factor Interactions; Unknown Cellular or Molecular Interaction.

What is Formaldehyde used for?

According to FDA labeling, Formaldehyde carries indications including: Fitful cough*. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Formaldehyde?

Formaldehyde is classified as Standardized Chemical Allergen, Immunologic Factor Interactions, Unknown Cellular or Molecular Interaction, Cell-mediated Immunity, Increased Histamine Release.

What are the brand names for Formaldehyde?

Formaldehyde is marketed under brand names including Forma-Ray, Formadon.