Glycerin

Mechanism-of-action class: Stool Bulking Activity.

• Uses For the temporary relief of burning and irritation due to dryness of the eye For the temporary relief of discomfort due to minor irritations of the eye or to exposure to wind or sun For use as a protectant against further irritation or to relieve dryness of the eye

Directions Instill 1 or 2 drops in the affected eye(s) as needed.

For external use only Do not use If solution changes color or becomes cloudy If you are sensitive to any ingredient in this product When using this product To avoid contamination do not touch tip of container to any surface Replace cap after using Stop use and ask a doctor if You experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

1. 1Drug Ineffective7,82933%
2. 2Oral Herpes2,42210%
3. 3Condition Aggravated2,0108.5%
4. 4Drug Administration Error1,7867.6%
5. 5Eye Irritation1,0554.5%
6. 6Eye Pain1,0104.3%
7. 7Incorrect Drug Administration Duration8063.4%
8. 8Off Label Use7743.3%
9. 9Pain7463.2%
10. 10Herpes Simplex7093.0%
11. 11Wrong Technique In Product Usage Process7093.0%
12. 12Macular Degeneration6722.8%
13. 13Incorrect Product Administration Duration6182.6%
14. 14Product Quality Issue6082.6%
15. 15Headache6022.6%

Recent PubMed references pinned to Glycerin as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Fungicidal Activity and In Silico Studies of Triazoles Derived From Glycerol Against Neocosmospora falciformis, A Causal Agent of Guava Tree Decline.
  Chemistry & biodiversity · 2026 · Costa AV, Correia AO, Benvindo Dos Anjos B, et al.
  PMID 42246282DOI 10.1002/cbdv.71389
• Glycerol-mediated improvement of heterologous aurachin D production in E. coli.
  Applied microbiology and biotechnology · 2026 · Korb J, Demir B, Graw K, et al.
  PMID 42216993DOI 10.1007/s00253-026-13890-2
• Step-growth grafted anion exchangers with hyperbranched polyglycerol modification for ion chromatography.
  Journal of chromatography. A · 2026 · Zhang K, Lou C, Diao Q, et al.
  PMID 42190344DOI 10.1016/j.chroma.2026.467123
• Preoperative opioid use and postoperative outcomes after primary percutaneous glycerin rhizotomy for trigeminal neuralgia.
  Clinical neurology and neurosurgery · 2026 · Ejimogu E, Kalluri AL, Carmichael A, et al.
  PMID 42173023DOI 10.1016/j.clineuro.2026.109485
• Dermal Regeneration Using Porogen-Leached Poly(glycerol sebacate)-Urethane Scaffolds with Controlled Morphology and Dual Porosity.
  ACS applied bio materials · 2026 · Mahmoudian Monfared M, Fathollah Maghsoudi MA, Arabsorkhi-Mishabi A, et al.
  PMID 42149958DOI 10.1021/acsabm.6c00432
• Valorization of glycerol via continuous etherification with ethanol: Thermodynamic modeling and process optimization.
  Waste management (New York, N.Y.) · 2026 · Marinho CM, Lemos COT, Resende KA, et al.
  PMID 42142452DOI 10.1016/j.wasman.2026.115600
• Glyceroneogenesis has a new PEP in its step(s).
  Cell · 2026 · Jerrett AE, Hathiramani NR, Spinelli JB, et al.
  PMID 42134304DOI 10.1016/j.cell.2026.04.035
• Glycerol-mediated nose-to-brain codelivery of anti-IL-17 and anti-CD73 antibodies enhances immunotherapy for melanoma brain metastases.
  Science advances · 2026 · Yang X, Yang H, Xu N, et al.
  PMID 42127192DOI 10.1126/sciadv.adx7966

The 10 most recently updated of 241 ClinicalTrials.gov registrations naming Glycerin as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Mechanisms of Cannabidiol and Sleep in the Context of Alcohol Use
  Not yet recruiting · Phase 2 · Interventional · 58 enrolled · University of Colorado, Boulder
  NCT07527338updated 2026-06-11
• Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain
  Recruiting · Phase 2 · Interventional · 24 enrolled · Wake Forest University Health Sciences
  NCT07053774updated 2026-05-26
• Elimination of Odor and Treatment of Malodorous Recalcitrant Wounds by Using Supraz and PRP-FG Versus Standard of Care
  Active not recruiting · Phase 2 · Phase 3 · Interventional · 40 enrolled · Mashhad University of Medical Sciences
  NCT05983302updated 2026-05-06
• Comprehensive Toileting Program
  Not yet recruiting · Phase 4 · Interventional · 150 enrolled · Emory University
  NCT07226739updated 2026-04-30
• Adjunctive Treatment With Vitamin D3 in Patients With Active IBD
  Suspended · Interventional · 100 enrolled · Massachusetts General Hospital
  NCT04225819updated 2026-04-27
• Mouthwashes for Gingivitis: Comparing a Hydrogen Peroxide-Hyaluronic Acid Mix, Hyaluronic Acid, and Chlorhexidine, A Triple-Blind Clinical Trial
  Completed · Interventional · 80 enrolled · Ramziyah Hayder Bakr
  NCT07031388updated 2026-04-23
• Gene Expression Study Between Two Dermal Injectables Hydroxylapatite Semi-permanent Filler
  Completed · Interventional · 21 enrolled · Galderma R&D
  NCT05620043updated 2026-04-15
• Effectiveness of Topical Magnetite Zinc Oxide Composite Nanoparticles in the Management of Oral Potentially Malignant Lesions
  Completed · Phase 1 · Phase 2 · Interventional · 24 enrolled · Ain Shams University
  NCT06271564updated 2026-04-07
• Topical Application of Engineered Lactobacillus Reuteri With a Zinc Sulfate-Tannic Acid MPN Coating for Acne
  Recruiting · Phase 2 · Interventional · 196 enrolled · Shenzhen People's Hospital
  NCT07366229updated 2026-04-06
• Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression
  Recruiting · Phase 2 · Interventional · 150 enrolled · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  NCT04363164updated 2026-04-06

Frequently asked questions

How does Glycerin work?

Mechanism-of-action class: Stool Bulking Activity.

What is Glycerin used for?

According to FDA labeling, Glycerin carries indications including: Uses For the temporary relief of burning and irritation due to dryness of the eye For the temporary relief of discomfort due to minor irritations of the eye or to exposure to wind or sun For use as a protectant against further irritation or to relieve dryness of the eye. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Glycerin?

Glycerin is classified as Enemas, Other drugs for constipation, Non-Standardized Chemical Allergen, Stool Bulking Activity, Cell-mediated Immunity, Emollient Activity, Increased Histamine Release, Increased IgG Production, Increased Large Intestinal Motility, Stimulation Large Intestine Fluid/Electrolyte Absorption.

What are the brand names for Glycerin?

Glycerin is marketed under brand names including Abreva Rapid Pain Relief, Blink Dry Eye, Chloraseptic Max Spray, Oasis Tears, Pedia-Lax Liquid Glycerin Suppositories, Pretz, ProcalAmine 3, Recticare Wipes.