Eye Pain
160 drugs37,752 FAERS reportsMedDRA PT
GET
/api/v1/reaction/eye-painReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D058447
A dull or sharp painful sensation associated with the outer or inner structures of the eyeball, having different causes.
Drugs reporting Eye Pain (160)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Escherichia Coli21055%
- 2Rose Bengal150%
- 3Cenegermin5,85649%
- 4Benoxinate222%
- 5Revakinagene Taroretcel120%
- 6Polysorbate 8021720%
- 7Chloroprocaine1019%
- 8Acoltremon48818%
- 9Medronate117%
- 10Polyvinyl Alcohol63716%
- 11Nepafenac45414%
- 12Aluminum Sesquichlorohydrate114%
- 13Amber114%
- 14Hypromellose 2910114%
- 15Loteprednol76913%
- 16Loteprednol Etabonate76913%
- 17Perfluorohexyloctane21513%
- 18Homatropine6913%
- 19Gramicidin113%
- 20Mineral Oil39812%
- 21Propylene77912%
- 22Propylene Glycol77912%
- 23Proparacaine6112%
- 24Carboxymethylcellulose1,43211%
- 25Alcaftadine10111%
- 26Potassium Iodide23211%
- 27Latanoprostene Bunod10511%
- 28Natamycin4010%
- 29Besifloxacin10110%
- 30Povidone84010%
- 31Tafluprost29310%
- 32Dextran 70110%
- 33Petrolatum3319.9%
- 34Pheniramine1839.6%
- 35Brolucizumab3188.9%
- 36Naphazoline1998.8%
- 37Lifitegrast1,4058.8%
- 38Fluorometholone2758.3%
- 39Cyclopentolate598.3%
- 40Voretigene Neparvovec127.9%
- 41Netarsudil2137.8%
- 42Lotilaner1917.6%
- 43Avacincaptad Pegol197.3%
- 44Tropicamide1137.1%
- 45Hypromellose1676.2%
- 46Difluprednate2316.1%
- 47Cysteamine846.1%
- 48Phentolamine95.8%
- 49Brinzolamide6995.6%
- 50Zinc Glycinate25.6%
- 51Mirdametinib45.3%
- 52Calcium Hydroxide15.3%
- 53Levobunolol55.2%
- 54Tetracaine315.0%
- 55Rutin44.9%
- 56Pilocarpine1624.9%
- 57Timolol1,7414.9%
- 58Dorzolamide8224.9%
- 59Povidone-iodine1994.9%
- 60Ofloxacin3474.8%
- 61Apraclonidine54.7%
- 62Iodine3634.6%
- 63Lanolin204.4%
- 64Glycerin1,0104.3%
- 65Ketotifen2714.2%
- 66Travoprost3484.1%
- 67Cyclosporine4,4113.9%
- 68Gatifloxacin673.8%
- 69Aflibercept1,2163.8%
- 70Ketorolac2063.7%
- 71Hekla Lava183.6%
- 72Ranibizumab9603.6%
- 73Latanoprost1,7763.5%
- 74Nitric Acid193.5%
- 75Ammonium Bromide173.5%
- 76Ammonium Phosphate173.5%
- 77Amoeba Proteus173.5%
- 78Antipyrine173.5%
- 79Arsenate173.5%
- 80Calcium Arsenate173.5%
- 81Calcium Hexafluorosilicate173.5%
- 82Calcium Hypophosphite173.5%
- 83Claviceps Purpurea Sclerotium173.5%
- 84Crataegus Laevigata Fruit173.5%
- 85Croton Oil173.5%
- 86Cupric Acetate173.5%
- 87Eutrochium Purpureum Root173.5%
- 88Ferrous Arsenate173.5%
- 89Gold Trichloride173.5%
- 90Hexafluorosilicate173.5%
- 91Lead Acetate173.5%
- 92Lead Iodide173.5%
- 93Mercuric Iodide173.5%
- 94Mercuric Oxide173.5%
- 95Mercuric Sulfate173.5%
- 96Mercuric Sulfide173.5%
- 97Molybdenum173.5%
- 98Moschus Moschiferus Musk Sac Resin173.5%
- 99Mycobacterium Tuberculosis173.5%
- 100Oxalic Acid173.5%
- 101Picrate173.5%
- 102Potassium Arsenite173.5%
- 103Quinine Arsenite173.5%
- 104Semecarpus Anacardium Juice173.5%
- 105Sodium Bromide173.5%
- 106Staphylococcus Epidermidis173.5%
- 107Staphylococcus Haemolyticus173.5%
- 108Staphylococcus Simulans173.5%
- 109Strontium Salicylate173.5%
- 110Sumbul173.5%
- 111Uranyl Nitrate173.5%
- 112Uranyl Nitrate Hexahydrate173.5%
- 113Vipera Berus Venom173.5%
- 114Virola Sebifera Resin173.5%
- 115Crotalus Horridus Horridus Venom173.5%
- 116Mercuric Cyanide173.5%
- 117Naja Naja Venom173.5%
- 118Zinc Valerate173.5%
- 119Streptococcus Pyogenes173.5%
- 120Barium Chloride173.5%
- 121Ferric Chloride173.5%
- 122Hydrogen Cyanide173.5%
- 123Sulfur Iodide173.5%
- 124Arsenic Triiodide173.5%
- 125Cyanide173.5%
- 126Calomel173.5%
- 127Turpentine173.5%
- 128Tin173.5%
- 129Barium Carbonate173.4%
- 130Antimony Trisulfide173.4%
- 131Ammonium Carbonate173.4%
- 132Calcium Iodide173.4%
- 133Kalmia Latifolia Leaf173.4%
- 134Chloride Hexahydrate173.4%
- 135Carteolol113.4%
- 136Polyethylene Glycol 4005363.3%
- 137Sepia Officinalis Juice173.3%
- 138Sulfuric Acid173.3%
- 139Lead183.3%
- 140Kerosene173.3%
- 141Bimatoprost9433.3%
- 142Aluminum Oxide173.3%
- 143Mercury173.3%
- 144Palladium173.3%
- 145Potassium Dichromate173.3%
- 146Calcium Fluoride173.3%
- 147Ichthammol173.2%
- 148Bromine173.2%
- 149Calcium Sulfate173.1%
- 150Tromethamine2062.9%
- 151Polymyxin B1372.8%
- 152Nickel172.8%
- 153Dibasic Potassium Phosphate172.7%
- 154Bepotastine172.7%
- 155Faricimab1672.3%
- 156Oxymetazoline1752.3%
- 157Tobramycin5452.0%
- 158Olopatadine2012.0%
- 159Aceclidine61.4%
- 160Bromfenac168—
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
- Eye Irritation58 shared · 0.34
- Ocular Hyperaemia54 shared · 0.33
- Vision Blurred63 shared · 0.32
- Paraesthesia70 shared · 0.30
- Muscle Spasms77 shared · 0.27
- Gait Disturbance76 shared · 0.25
- Alopecia71 shared · 0.24
- Visual Impairment42 shared · 0.22
- Feeling Abnormal76 shared · 0.21
- Abdominal Pain Upper82 shared · 0.21
Literature
Recent PubMed references pinned to Eye Pain as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Efficacy and safety of clobetasol propionate ophthalmic nanoemulsion for treating intraocular inflammation and pain associated with cataract surgery: two phase 3 multicentre, randomised, placebo-controlled, double-masked clinical studies.BMJ open · 2026 · Schwartz A, Wellish K, Zaman F, et al.PMID 42192627DOI 10.1136/bmjopen-2025-101177
- Eye pain and ocular surface characteristics in Postural Orthostatic Tachycardia Syndrome (POTS): The role of autonomic dysfunction.The ocular surface · 2025 · Karakus S, Huang JJ, Yashar M, et al.PMID 42183595DOI 10.1016/j.jtos.2025.10.009
- Tramadol Eye Drop Reduces Ocular Nocifensive Behavior Not Primarily Mediated by μ-Opioid Receptor Activation in a Rat Dry Eye Model.Biological & pharmaceutical bulletin · 2026 · Nagaoka S, Takai Y, Kiyoi T, et al.PMID 42128871DOI 10.1248/bpb.b26-00041
- [Nociceptive and neuropathic pain: impact of the ocular surface].Vestnik oftalmologii · 2026 · Sheludchenko NV, Avetisov SE, Vasileva AP, et al.PMID 42048103DOI 10.17116/oftalma2026142021107
- Effectiveness of ultrasound-guided pulsed radiofrequency of the stellate ganglion for pain management in painful blind eye: a prospective case series.Journal of translational medicine · 2026 · Sanatkar M, Haydar AA, Espahbodi E, et al.PMID 41998657DOI 10.1186/s12967-026-08141-x
- Randomized Pilot Study of Transcutaneous Electrical Nerve Stimulation for Neuropathic/Nociplastic Ocular Pain.American journal of ophthalmology · 2026 · Shields C, Qazi S, Zaldivar A, et al.PMID 41812852DOI 10.1016/j.ajo.2026.03.008
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.