Hydrofluoric Acid
US-FDASourced from openFDA
GET
/api/v1/drug/hydrofluoric-acidIndications
Sourced from openFDA- Uses: See symptoms on front panel.
Dosage & administration
Sourced from openFDAAdults and children: At the onset of symptoms, dissolve 5 pellets under the tongue 3 times a day until symptoms are relieved or as directed by a doctor.
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
1,530 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Fatigue1389.0%
- 2Nausea1228.0%
- 3Dizziness1066.9%
- 4Pain1016.6%
- 5Diarrhoea976.3%
- 6Headache976.3%
- 7Arthralgia865.6%
- 8Drug Ineffective845.5%
- 9Dyspnoea785.1%
- 10Pain In Extremity734.8%
- 11Pruritus684.4%
- 12Asthenia664.3%
- 13Vomiting634.1%
- 14Insomnia603.9%
- 15Rash563.7%
Literature
Recent PubMed references pinned to Hydrofluoric Acid as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Anhydrous stannous fluoride toothpaste in dentin hypersensitivity: clinician-assessed and patient-reported outcomes from two controlled trials.Clinical oral investigations · 2026 · Qiu J, Creeth JE, Mohammad A, et al.PMID 42262610DOI 10.1007/s00784-026-06942-4
- Spatiotemporal variability, driving factors, and potential human health risks of fluoride and nitrate in surface water and groundwater of a sandy desert lake basin, Northwest China.Journal of environmental sciences (China) · 2026 · Li X, Li M, Qu S, et al.PMID 42217873DOI 10.1016/j.jes.2025.12.022
- From tooth to gut: Proteomic evidence of systemic dysregulation in fluorosis.Ecotoxicology and environmental safety · 2026 · Pongsapipatana N, Gavila P, Khieota T, et al.PMID 42202465DOI 10.1016/j.ecoenv.2026.120310
- Integrated hydrochemical and health-risk assessment of fluoride and major ions in groundwater from hattar and gadoon industrial estates, pakistan.Environmental geochemistry and health · 2026 · Ahmad T, Qadir A, Khan MA, et al.PMID 42201498DOI 10.1007/s10653-026-03261-1
- Preservation-to-Precision in Severe Early Childhood Caries: A Narrative Review of Silver Diamine Fluoride-When "Buying Time" Must Not Become "Selling Time".International journal of environmental research and public health · 2026 · Baghdadi ZDPMID 42196748DOI 10.3390/ijerph23050656
- Morphological, Histochemical, and Proteomic Analysis of the Effects of Fluoride and Amoxicillin, with Calcium and Vitamin D Supplementation, on Dental Enamel Formation.Calcified tissue international · 2026 · Porto IM, da Silva AAS, Dos Santos JVA, et al.PMID 42184017DOI 10.1007/s00223-026-01548-0
- Melatonin alleviates fluoride-induced developmental neurotoxicity by restoring SIRT3/HIF-1α axis-mediated mitochondrial dysfunction and reversing energy metabolism reprogramming.Ecotoxicology and environmental safety · 2026 · Ma R, Wang C, Qin W, et al.PMID 42176635DOI 10.1016/j.ecoenv.2026.120301
- Ecotoxicological insights into fluoride pollution affecting soil, plant and human health.Ecotoxicology and environmental safety · 2026 · Farooqi ZUR, Karim A, Qadir AA, et al.PMID 42172710DOI 10.1016/j.ecoenv.2026.120295
Clinical trials
The 10 most recently updated of 195 ClinicalTrials.gov registrations naming Hydrofluoric Acid as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Effect of MI Paste Plus™ on Streptococcus Mutans and White Spot Lesions in Fixed OrthodonticsRecruiting · Interventional · 200 enrolled · Cardenal Herrera UniversityNCT07244991updated 2026-03-27
- Bioadhesive Film of Acmella Oleracea (Jambu) in the Reduction of Post-bleaching Dental Sensitivity Caused by Bleaching With 35% Hydrogen Peroxide.Completed · Phase 3 · Interventional · 72 enrolled · Universidade Federal do ParaNCT07478640updated 2026-03-17
- Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel DentifriceRecruiting · Phase 3 · Interventional · 850 enrolled · HALEONNCT07215767updated 2026-02-05
- Effect Of Silverdiamine Fluoride Gel, Sodium Fluoride With CPP-ACP, APF On Early Childhood Caries - A Randomised Controlled TrialActive not recruiting · Phase 2 · Interventional · 90 enrolled · University of JazanNCT07371117updated 2026-01-27
- Clinical Comparison of CAD/CAM Nanohybrid Composite and Hybrid Ceramic Overlays in Children With Molar-Incisor HypomineralisationCompleted · Interventional · 20 enrolled · Alp AkçaNCT06987448updated 2026-01-21
- Neonatal Brain Ultrasound With CEUS and ElastographyRecruiting · Phase 3 · Interventional · 100 enrolled · Turku University HospitalNCT05648812updated 2026-01-15
- Preterm Neonates Brain Ultrasound With CEUS and ElastographyWithdrawn · Phase 3 · Interventional · 0 enrolled · Turku University HospitalNCT05694611updated 2026-01-15
- Heart Failure Polypill at a Safety Net HospitalCompleted · Phase 2 · Interventional · 35 enrolled · University of California, San FranciscoNCT06029712updated 2025-12-31
- Air Tamponade Versus Fluorinated Gas Tamponade for Rhegmatogenous Retinal DetachmentNot yet recruiting · Interventional · 150 enrolled · Liverpool University Hospitals NHS Foundation TrustNCT07034469updated 2025-12-24
- Efficacy of Toothpaste Containing 0.454% Stannous Fluoride as Compared to a Regular Fluoride Toothpaste Containing 0.76% Sodium Monofluorophosphate in Controlling Supragingival Calculus Formation Over a 12-week Period.Completed · Phase 2 · Phase 3 · Interventional · 100 enrolled · Colgate PalmoliveNCT07223060updated 2025-12-11
Frequently asked questions
- What is Hydrofluoric Acid used for?
- According to FDA labeling, Hydrofluoric Acid carries indications including: Uses: See symptoms on front panel.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
Note. Data for
hydrofluoric-acid is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.