Interleukin-10
/api/v1/drug/interleukin-10Indications
Sourced from openFDA- Directions : Take 15 minutes before meals.
Dosage & administration
Sourced from openFDADIRECTIONS Adults and children 12 years and older 20 drops twice a day in a little water. Hold in the mouth for about 30 seconds then swallow. Children between 12 years and 6 years of age 10 drops twice a day in a little water. Hold in the mouth for about 30 seconds then swallow. Children under 6 years 5 drops twice a day in a glass of water.
Warnings & precautions
Sourced from openFDAStop use and ask doctor if symptoms worsen or persist more than 5 days. If pregnant or breast-feeding ask a doctor professional before use. Keep this and all medicines out of reach of children. Contains ethyl alcohol 30%
FAERS reports
- 1Off Label Use5315%
- 2Pyrexia349.5%
- 3Hypotension329.0%
- 4Fatigue236.4%
- 5Nausea236.4%
- 6Cardiotoxicity226.2%
- 7Chills226.2%
- 8Decreased Appetite195.3%
- 9Diarrhoea195.3%
- 10Malignant Neoplasm Progression195.3%
- 11Anaemia174.8%
- 12Disease Progression174.8%
- 13Product Use In Unapproved Indication154.2%
- 14Vomiting154.2%
- 15Death143.9%
Literature
Recent PubMed references pinned to Interleukin-10 as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Extracellular vesicles from glycolytic mesenchymal stromal cells restrain arthritis progression via IL-10-Producing T and B cells.Theranostics · 2026 · Lara-Barba E, Lagos R, Flores-Elías Y, et al.PMID 42244992DOI 10.7150/thno.123898
- Targeting Fatty Acid Synthase With Berberine Promotes IL-10 Production in Macrophages and Prevents Relapse in a Murine Colitis Model.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026 · Hayashi S, Ogawa Y, Wakabayashi N, et al.PMID 42240471DOI 10.1096/fj.202504287R
- In situ nanozyme assembly amplification enables sub-femtomolar-level colorimetric immunoassay.Mikrochimica acta · 2026 · Peng X, Lin M, Zhou R, et al.PMID 42234191DOI 10.1007/s00604-026-08167-4
- Melatonin Accelerates Diabetic Wound Repair via Modulation of Tenascin C and Interleukin-10 in Fibroblasts.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026 · Sun J, Qian Y, Chen S, et al.PMID 42233548DOI 10.1096/fj.202600440RR
- Blood Plasma Cytokine Concentration in Female Rats with Temporomandibular Joint Osteoarthritis.Bulletin of experimental biology and medicine · 2026 · Vinnikova VD, Pak OS, Vorozhko IV, et al.PMID 42230498DOI 10.1007/s10517-026-06676-z
- IL-27 blockade suppresses IL-10 modification in Th1 cells and promotes intracranial aneurysms rupture.Biochemical and biophysical research communications · 2026 · Zeng X, Zang F, Bu G, et al.PMID 42184471DOI 10.1016/j.bbrc.2026.154004
- Polydopamine-coated hollow mesoporous silica nanoparticles loaded with lupeol regulates immune microenvironment in gastric cancer mice by down-regulating IL-10 through regulating NF-κb signaling.Pakistan journal of pharmaceutical sciences · 2026 · Zhang H, Wei X, Guo J, et al.PMID 42170971DOI 10.36721/PJPS.2026.39.7.194.1
- Engineering interleukin-10 for therapeutic applications.International review of cell and molecular biology · 2026 · Zheng Y, García-Fuentes R, Risson A, et al.PMID 42161469DOI 10.1016/bs.ircmb.2026.02.006
Clinical trials
The 10 most recently updated of 68 ClinicalTrials.gov registrations naming Interleukin-10 as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Local Inflammation in Arrhythmogenic Right Ventricular CardiomyopathyRecruiting · Interventional · 80 enrolled · University Hospital, ToulouseNCT05209776updated 2026-06-01
- Investigation of the Relationship Between Periodontitis and Sleep QualityRecruiting · Observational · 48 enrolled · Uskudar UniversityNCT07421960updated 2026-02-19
- DETERMINATION OF THE EFFECTS OF STAINLESS STEEL CROWNS CEMENTED WITH RESIN CEMENTS ON INTERLEUKIN-10, 12, 18 LEVELS IN GINGIVAL CREVICULAR FLUIDNot yet recruiting · Interventional · 45 enrolled · Afyonkarahisar Health Sciences UniversityNCT07421206updated 2026-02-19
- Interleukin 8 and10 Levels Changes in Teeth With Necrotic Pulp and Apical PeriodontitisCompleted · Interventional · 22 enrolled · Faculty of Dental Medicine for GirlsNCT06713174updated 2026-02-18
- Pain, Central Sensitization and Psychoemotional State in Patients With Chronic Masticatory Muscle PainEnrolling by invitation · Observational · 102 enrolled · Wroclaw Medical UniversityNCT05676827updated 2026-02-03
- Aerobic Exercise vs Physiological Ischemic Training in Stage 2 HypertensionCompleted · Interventional · 60 enrolled · Universitas PadjadjaranNCT07375407updated 2026-02-02
- Association of Periodontal Status and Smoking With Salivary Inflammasome MarkersRecruiting · Observational · 116 enrolled · Uskudar UniversityNCT07312552updated 2026-01-21
- Effect of Dapagliflozin on Interleukin 10 in SepsisNot yet recruiting · Observational · 64 enrolled · Minia UniversityNCT07206160updated 2025-10-03
- Prevention of Doxorubicin-induced Cardiotoxicity in Breast Cancer PatientsCompleted · Phase 2 · Interventional · 80 enrolled · British University In EgyptNCT06703593updated 2025-10-01
- Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ TumorsActive not recruiting · Phase 1 · Interventional · 39 enrolled · DEKA BiosciencesNCT05704985updated 2025-05-29
Frequently asked questions
- What is Interleukin-10 used for?
- According to FDA labeling, Interleukin-10 carries indications including: Directions : Take 15 minutes before meals.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
interleukin-10 is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.