Chills
113 drugs21,052 FAERS reportsMedDRA PT
GET
/api/v1/reaction/chillsReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D023341
The sudden sensation of being cold. It may be accompanied by SHIVERING.
Drugs reporting Chills (113)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Difamilast1100%
- 2Escherichia Coli21155%
- 3Aldosterone150%
- 4Androsterone150%
- 5Follicle Stimulating Hormone150%
- 6Nogapendekin Alfa Inbakicept517%
- 7Medronate117%
- 8Zanidatamab716%
- 9Soybean Oil16415%
- 10Oritavancin17315%
- 11Tarlatamab114%
- 12Margetuximab312%
- 13Potassium Iodide23111%
- 14Trisodium Citrate75611%
- 15Ofatumumab3,45911%
- 16Tebentafusp5510%
- 17Fexinidazole110%
- 18Sipuleucel-t5289.5%
- 19Manganese Sulfate78.9%
- 20Amifostine698.6%
- 21Lifileucel208.4%
- 22Cobaltous Chloride38.1%
- 23Exametazime37.9%
- 24Aluminum Zirconium Trichlorohydrex Gly17.7%
- 25Telavancin97.6%
- 26Lecanemab2397.2%
- 27Teplizumab346.9%
- 28Pentoxifylline2756.5%
- 29Dabrafenib1,3146.4%
- 30Aspartic Acid326.3%
- 31Interleukin-10226.2%
- 32Interleukin-11226.2%
- 33Interleukin-3226.2%
- 34Interleukin-5226.2%
- 35Etranacogene Dezaparvovec36.0%
- 36Florbetaben15.9%
- 37Nadofaragene Firadenovec265.8%
- 38Acetaldehyde15.6%
- 39Trametinib1,2725.4%
- 40Sinusitisinum35.4%
- 41Agalsidase Beta4745.3%
- 42Oxyquinoline25.3%
- 43Aldesleukin605.0%
- 44Alanine355.0%
- 45Histidine355.0%
- 46Isoleucine355.0%
- 47Proline355.0%
- 48Threonine355.0%
- 49Leucine354.9%
- 50Methazolamide164.9%
- 51Serine354.9%
- 52Methionine354.9%
- 53Valine354.9%
- 54Barium Iodate24.7%
- 55Rifapentine234.6%
- 56Sincalide74.6%
- 57Phenylalanine354.4%
- 58Gemtuzumab Ozogamicin1574.4%
- 59Bicisate14.3%
- 60Mebrofenin44.3%
- 61Iohexol3394.2%
- 62Peginterferon Alfa-2a2,1914.1%
- 63Interferon Gamma-1b554.0%
- 64Difenoxin13.8%
- 65Lofexidine63.8%
- 66Glycine383.7%
- 67Pegunigalsidase Alfa113.7%
- 68Pentostatin383.6%
- 69Artemether73.6%
- 70Lumefantrine73.6%
- 71Linvoseltamab13.6%
- 72Sodium Gluconate43.5%
- 73Phendimetrazine23.5%
- 74Zafirlukast303.5%
- 75Sodium Ascorbate1093.4%
- 76Ascorbate1093.4%
- 77Sargramostim573.4%
- 78Iopromide1313.3%
- 79Ferumoxytol623.3%
- 80Zoledronic Acid1,2633.2%
- 81Mogamulizumab403.1%
- 82Ribavirin2,0083.1%
- 83Interferon Beta-1b5953.1%
- 84Obinutuzumab4823.1%
- 85Donanemab603.0%
- 86Sodium Sulfate3703.0%
- 87Naloxegol1122.9%
- 88Iodixanol962.8%
- 89Potassium Sulfate1382.8%
- 90Imiquimod612.7%
- 91Arginine452.7%
- 92Vitamin D362.7%
- 93Fluorescein242.7%
- 94Avelumab1012.6%
- 95Peginterferon Beta-1a3302.5%
- 96Dalbavancin282.4%
- 97Tryptophan512.4%
- 98Tyrosine492.4%
- 99Daptomycin2092.4%
- 100Glatiramer1,4622.4%
- 101Ceftobiprole12.3%
- 102Degarelix1162.3%
- 103Chromium102.2%
- 104Oxidronate32.2%
- 105Telisotuzumab12.2%
- 106Thiosulfate112.1%
- 107Lysine472.1%
- 108Tecovirimat21.9%
- 109Imetelstat31.9%
- 110Deuruxolitinib11.8%
- 111Tetrofosmin101.6%
- 112Ceftaroline121.6%
- 113Ceftaroline Fosamil121.6%
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
- Chest Discomfort25 shared · 0.14
- Parenteral Nutrition Associated Liver Disease15 shared · 0.13
- Influenza Like Illness17 shared · 0.13
- Palpitations19 shared · 0.13
- Extravasation13 shared · 0.11
- Erythema29 shared · 0.10
- Hyperhidrosis17 shared · 0.10
- Infusion Related Reaction18 shared · 0.10
- Cholestasis11 shared · 0.09
- General Physical Health Deterioration16 shared · 0.09
Literature
Recent PubMed references pinned to Chills as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Diagnostic accuracy of self-reported food consumption and shaking chills in predicting bacteremia in outpatients: A prospective, multicenter observational study.PloS one · 2025 · Komatsu T, Inoue K, Someya Y, et al.PMID 40627656DOI 10.1371/journal.pone.0327789
- Added Value of Shaking Chills for Predicting Bacteremia in Patients with Suspected Infection.Journal of general internal medicine · 2025 · Kudo M, Takada T, Fujii K, et al.PMID 39707092DOI 10.1007/s11606-024-09291-8
- Utility of shaking chills as a diagnostic sign for bacteremia in adults: a systematic review and meta-analysis.BMC medicine · 2024 · Aita T, Nakagawa H, Takahashi S, et al.PMID 38863066DOI 10.1186/s12916-024-03467-z
- ChillsDB 2.0: Individual Differences in Aesthetic Chills Among 2,900+ Southern California Participants.Scientific data · 2023 · Schoeller F, Christov Moore L, Lynch C, et al.PMID 38129439DOI 10.1038/s41597-023-02816-6
- ChillsDB: A Gold Standard for Aesthetic Chills Stimuli.Scientific data · 2023 · Schoeller F, Jain A, Horowitz AH, et al.PMID 37210402DOI 10.1038/s41597-023-02064-8
- 71-Year-Old Man With Fever, Chills, and Malaise.Mayo Clinic proceedings · 2023 · Alabdaljabar MS, Ellis M, Issa M, et al.PMID 37125974DOI 10.1016/j.mayocp.2022.12.021
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.