Interleukin-11
/api/v1/drug/interleukin-11Indications
Sourced from openFDA- Take 15 minutes before meals.
Dosage & administration
Sourced from openFDADIRECTIONS Take 15 minutes before meals. Adults and children 12 years and older 20 drops twice a day in a little water. Hold in the mouth for about 30 seconds then swallow. Children between 12 years and 6 years of age 10 drops twice a day in a little water. Hold in the mouth for about 30 seconds then swallow. Children under 6 years 5 drops twice a day in a glass of water.
Warnings & precautions
Sourced from openFDAKeep this and all medicines out of reach of children
FAERS reports
- 1Off Label Use5315%
- 2Pyrexia349.5%
- 3Hypotension329.0%
- 4Fatigue236.4%
- 5Nausea236.4%
- 6Cardiotoxicity226.2%
- 7Chills226.2%
- 8Decreased Appetite195.3%
- 9Diarrhoea195.3%
- 10Malignant Neoplasm Progression195.3%
- 11Anaemia174.8%
- 12Disease Progression174.8%
- 13Product Use In Unapproved Indication154.2%
- 14Vomiting154.2%
- 15Death143.9%
Literature
Recent PubMed references pinned to Interleukin-11 as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Serum Level of Interleukin-11 Is Associated with the Severity of Hepatic Fibrosis in Adults with Metabolic Dysfunction-Associated Steatotic Liver Disease.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2026 · Xue Y, Fu H, Wu H, et al.PMID 42227820DOI 10.1177/10799907261432064
- Gαi1 and Gαi3 mediate IL-11-induced signal transduction and are potential therapeutic targets for LUAD.Cell death & disease · 2026 · Luo G, Hu W, Yang J, et al.PMID 42034606DOI 10.1038/s41419-026-08637-w
- Generation and characterization of the Il11-Cre knock-in mouse.Transgenic research · 2026 · Zhou X, Xie Z, Liu W, et al.PMID 41945189DOI 10.1007/s11248-026-00491-y
- Interleukin 11-Induced MicroRNAs as Functional Mediators and Circulating Biomarkers of Cardiac Fibrosis.Circulation research · 2026 · Tikhomirov R, Boichenko V, Reilly-O'Donnell B, et al.PMID 41841256DOI 10.1161/CIRCRESAHA.125.326799
- The role of IL-11 in chronic diseases.Frontiers in immunology · 2026 · Zhang J, Leng Y, Li W, et al.PMID 41789107DOI 10.3389/fimmu.2026.1763360
- IL-11 acts as an alarmin-like pro-inflammatory mediator regulating mucosal responses during helminth infection.Mucosal immunology · 2026 · Gazzinelli-Guimaraes PH, Bara-Garcia P, Kupritz J, et al.PMID 41548664DOI 10.1016/j.mucimm.2026.01.005
- Therapeutic effect of IL-11 inhibition on the pathogenesis of thyroid eye disease.Journal of molecular endocrinology · 2026 · Yoon HJ, Park HY, Kim JY, et al.PMID 41432126DOI 10.1530/JME-25-0080
- IL-11 as a potential diagnostic and prognostic biomarker in oral submucous fibrosis-related oral squamous cell carcinoma: A single-center exploratory study.Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery · 2026 · Liu Y, Quan HPMID 41423377DOI 10.1016/j.jcms.2025.11.017
Clinical trials
The 10 most recently updated of 27 ClinicalTrials.gov registrations naming Interleukin-11 as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- A Phase II Study of 9MW3811 in Patients With Pathological ScarRecruiting · Phase 2 · Interventional · 30 enrolled · Mabwell (Shanghai) Bioscience Co., Ltd.NCT07576608updated 2026-05-08
- A Study on the Treatment of CTIT of the Efficacy and Safety With Romiplostim N01 Compared to Recombinant Human Interleukin-11Recruiting · Phase 3 · Interventional · 88 enrolled · The First Affiliated Hospital with Nanjing Medical UniversityNCT06759636updated 2026-04-14
- G-CSF Combined With IL-11 on Hematopoietic Reconstitution After Autologous Hematopoietic Stem Cell TransplantationRecruiting · Phase 2 · Interventional · 224 enrolled · Fudan UniversityNCT07362810updated 2026-01-23
- A Multicenter, Open-label, Randomized Controlled Trial Evaluating the Efficacy and Safety of Romiplostim N01 in the Treatment of Thrombocytopenia Associated With Concurrent/Sequential Chemoradiotherapy and Chemotherapy Combined With/Without Immunotherapy in Solid TumorsNot yet recruiting · Interventional · 106 enrolled · Jun wangNCT07185893updated 2025-09-22
- Clinical Study Protocol of Maintenance Therapy With Venetoclax in Elderly Patients With AML in First Complete RemissionRecruiting · Interventional · 100 enrolled · The First Affiliated Hospital with Nanjing Medical UniversityNCT05909293updated 2023-06-18
- To Evaluate Thrombosis Risk in Chemotherapy Patients With Solid Tumors Who Receiving Thrombocytopenia TreatmentCompleted · Observational · 3,494 enrolled · Liaoning Cancer Hospital & InstituteNCT05688306updated 2023-01-18
- Efficacy of Avatrombopag in Thrombocytopenic Patients With Chronic Liver Disease Undergoing an Elective ProcedureUnknown · Phase 4 · Interventional · 476 enrolled · Chinese PLA General HospitalNCT04915287updated 2022-11-15
- Measurement of Oncostatin M, Leukemia Inhibitory Factor and Interleukin-11 Levels of Patients With Periodontal DiseaseCompleted · Interventional · 72 enrolled · Ataturk UniversityNCT04597073updated 2020-10-22
- A Phase Ⅲa Study of Genetically Modified Recombinant Human Interleukin-11Completed · Phase 3 · Interventional · 62 enrolled · Beijing Northland Biotech. Co., Ltd.NCT01663441updated 2020-09-16
- Interleukin-11 Can Prevent and Treat of Radioactive Oral MucitisUnknown · Phase 3 · Interventional · 300 enrolled · Zhejiang Cancer HospitalNCT03720340updated 2020-08-11
Frequently asked questions
- What is Interleukin-11 used for?
- According to FDA labeling, Interleukin-11 carries indications including: Take 15 minutes before meals.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
interleukin-11 is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.