Iodine
Iodine productsUnknown Cellular or Molecular InteractionUnknown Physiological EffectUS-FDASourced from openFDA
GET
/api/v1/drug/iodineMechanism of action
Sourced from openFDAMechanism-of-action class: Unknown Cellular or Molecular Interaction.
Indications
Sourced from openFDA- Uses First aid to help prevent infection in minor cuts scrapes burns
Dosage & administration
Sourced from openFDADirections clean the affected area spray a small amount of the product on the area 1 to 3 times daily may be covered with a sterile bandage if bandaged, let dry first
Warnings & precautions
Sourced from openFDAFor external use only
Approval history
Sourced from openFDA- Dec 17, 1986NDANDA018634Alcon Pharms Ltd
- Sep 29, 2006NDANDA021586Solventum
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
7,960 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Drug Hypersensitivity1,43818%
- 2Off Label Use7189.0%
- 3Nausea6488.1%
- 4Fatigue5356.7%
- 5Diarrhoea5226.6%
- 6Dyspnoea4946.2%
- 7Drug Ineffective4916.2%
- 8Headache4846.1%
- 9Rash4705.9%
- 10Pain4645.8%
- 11Arthralgia4495.6%
- 12Endophthalmitis4305.4%
- 13Vomiting4225.3%
- 14Pruritus4105.2%
- 15Dizziness3934.9%
Literature
Recent PubMed references pinned to Iodine as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Postoperative stimulated thyroglobulin and the ps-tg/TSH ratio enhance the 2025 ATA risk stratification for predicting radioiodine response in papillary thyroid carcinoma.Annals of medicine · 2026 · Ran B, Zhang H, Li Y, et al.PMID 42252965DOI 10.1080/07853890.2026.2657641
- Chinese expert consensus: Radioactive iodine-125 seed interstitial brachytherapy for retroperitoneal lymph node metastases (2024 edition).Journal of cancer research and therapeutics · 2026 · Wang J, Zhang H, Zhang F, et al.PMID 42241160DOI 10.4103/jcrt.jcrt_1737_24
- Clinical and metabolic factors associated with response to postoperative radioactive iodine therapy in Chinese obese patients with papillary thyroid carcinoma.Frontiers in endocrinology · 2026 · Zhou Y, Hou Y, Hu S, et al.PMID 42238248DOI 10.3389/fendo.2026.1836784
- Comparative study of 131I released during a nuclear accident.Radiation protection dosimetry · 2026 · Dadda Khorsi A, Bouam A, Chiridi Deghal AL, et al.PMID 42233305DOI 10.1093/rpd/ncaf172
- Preparation, characterization, and calibration of two fundamental reagents for the immunoradiometric (IRMA-125I) thyroid-stimulating hormone assay.Radiation protection dosimetry · 2026 · Hamdi N, Asselah D, Nouri R, et al.PMID 42233298DOI 10.1093/rpd/ncaf187
- [Changes in ovarian function and ovarian reserve after combined treatment for differentiated thyroid cancer].Problemy endokrinologii · 2026 · Korchagina MO, Andreeva EN, Sheremeta MS, et al.PMID 42227096DOI 10.14341/probl13635
- Preliminary volume-based optimization of radioactive iodine dose without radioactive iodine uptake in Graves' disease.Frontiers in endocrinology · 2026 · Keeratitanont K, Limchareon S, Kongpromsuk S, et al.PMID 42222089DOI 10.3389/fendo.2026.1823030
- Photon counting computed tomography in head and neck squamous cell carcinoma: iodine concentration and histopathological features.Journal of cancer research and clinical oncology · 2026 · Surov A, Diallo-Danebrock R, Sonnemann H, et al.PMID 42219395DOI 10.1007/s00432-026-06509-6
Clinical trials
The 10 most recently updated of 1,251 ClinicalTrials.gov registrations naming Iodine as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- A Trial to Study the Influence of Ultrasound Guidance on the Complications of Central CatheterTerminated · Interventional · 264 enrolled · Centre Hospitalier Universitaire, AmiensNCT01154465updated 2026-06-12
- 177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid CancerNot yet recruiting · Phase 1 · Phase 2 · Interventional · 18 enrolled · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT06991738updated 2026-06-12
- Optimization of Beta-lactam Dosing in Critically Ill Patients With Cystatin C (OPTIMIZE-GNI)Recruiting · Phase 4 · Interventional · 200 enrolled · National Institute of Allergy and Infectious Diseases (NIAID)NCT06709521updated 2026-06-12
- 131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in Advanced Sickle Cell Disease (SCD)Recruiting · Phase 1 · Interventional · 24 enrolled · Columbia UniversityNCT07015684updated 2026-06-10
- Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell LymphomaRecruiting · Phase 1 · Interventional · 21 enrolled · Mayo ClinicNCT06508463updated 2026-06-10
- A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or LymphomaRecruiting · Phase 1 · Interventional · 99 enrolled · Mayo ClinicNCT03017820updated 2026-06-10
- Study of PET Imaging With 18F-TFB in Patients With Thyroid CancerActive not recruiting · Interventional · 5 enrolled · Memorial Sloan Kettering Cancer CenterNCT03196518updated 2026-06-08
- VSV-IFNβ-NIS With Ipilimumab and Nivolumab for the Treatment of Advanced or Metastatic Clear Cell Renal Cell CarcinomaRecruiting · Phase 2 · Interventional · 18 enrolled · Mayo ClinicNCT07510334updated 2026-06-05
- Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid CancerActive not recruiting · Phase 3 · Interventional · 153 enrolled · Novartis PharmaceuticalsNCT04940052updated 2026-06-04
- Efficacy of Transversus Abdominis Plane Block in Alleviating Acute AppendicitisCompleted · Interventional · 105 enrolled · Ankara City Hospital BilkentNCT06808737updated 2026-06-04
Frequently asked questions
- How does Iodine work?
- Mechanism-of-action class: Unknown Cellular or Molecular Interaction.
- What is Iodine used for?
- According to FDA labeling, Iodine carries indications including: Uses First aid to help prevent infection in minor cuts scrapes burns. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Iodine?
- Iodine is classified as Iodine products, Unknown Cellular or Molecular Interaction, Unknown Physiological Effect.
- What are the brand names for Iodine?
- Iodine is marketed under brand names including Absorbine Veterinary Liniment, Barrier-Dyne, BovaPro, Bovadine, ChoreMate One-Shot, Dairyland Brand Controlled Iodine Teat Dip, Defend II, Della Soft.
Note. Data for
iodine is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.