Levomefolate
GET
/api/v1/drug/levomefolateMechanism of action
Sourced from openFDAMechanism-of-action class: Enzyme Interactions.
Warnings & precautions
Sourced from openFDAAllergen Warning Contains fish gelatin and soy oil.
Approval history
Sourced from openFDA- Sep 24, 2010NDANDA022532Bayer Hlthcare
- Dec 16, 2010NDANDA022574Bayer Hlthcare
- Dec 12, 2017ANDAANDA205948Lupin
- Jun 13, 2018ANDAANDA205947Lupin
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
1,898 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Pulmonary Embolism34318%
- 2Deep Vein Thrombosis27514%
- 3Injury25413%
- 4Pain22712%
- 5Emotional Distress1759.2%
- 6Anxiety1558.2%
- 7Drug Dose Omission1125.9%
- 8No Adverse Event1025.4%
- 9General Physical Health Deterioration955.0%
- 10Anhedonia844.4%
- 11Metrorrhagia844.4%
- 12Nausea844.4%
- 13Off Label Use733.8%
- 14Dyspnoea703.7%
- 15Headache653.4%
Clinical trials
The 10 most recently updated of 64 ClinicalTrials.gov registrations naming Levomefolate as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Use of Ritual Prenatal Multivitamins for PregnancyCompleted · Interventional · 80 enrolled · City University of New YorkNCT05673070updated 2026-05-19
- Clinical Antenatal Randomised Study to CharactErise Key Roles of TetrahydroFOLate in HyperTensive PregnanciesRecruiting · Interventional · 128 enrolled · University of OxfordNCT05434195updated 2026-04-29
- Interest of Myo-inositol Supplementation in Women With Polycystic Ovarian SyndromeRecruiting · Phase 3 · Interventional · 276 enrolled · University Hospital, LilleNCT03059173updated 2026-04-22
- Effects of 5-Methyltetrahydrofolic Acid Supplementation on Maternal Health and One-Carbon Metabolism During LactationNot yet recruiting · Phase 1 · Phase 2 · Interventional · 36 enrolled · Fundació Sant Joan de DéuNCT07508917updated 2026-04-02
- Pharmacokinetic Study of Eicosapentaenoic Acid (EPA) and Calcium L-5-Methyltetrahydrofolate (L-5-MTHF) After Administration of CreNeuroS® CNS Fish Oil Plus Softgels in Healthy Subjects Under Fasting ConditionsNot yet recruiting · Interventional · 32 enrolled · Sichuan Credit Pharmaceutical Co., Ltd.NCT07461649updated 2026-03-16
- Optimal Nutrition for Prevention of Hypertension in PregnancyActive not recruiting · Interventional · 2,250 enrolled · University of UlsterNCT04723836updated 2025-10-07
- Feasibility Test of Folic Acid on Acute Kidney InjuryNot yet recruiting · Early phase 1 · Interventional · 90 enrolled · The University of Hong KongNCT07013136updated 2025-07-15
- Adjunctive Treatment With L-methylfolate for Treatment-Resistant Generalized Anxiety Disorder: a Pilot StudyRecruiting · Phase 4 · Interventional · 10 enrolled · Queen's UniversityNCT06218030updated 2025-05-25
- B-Complex: A Nutraceutical SANS CountermeasureRecruiting · Phase 1 · Interventional · 16 enrolled · National Aeronautics and Space Administration (NASA)NCT05366933updated 2025-05-22
- Comparison of The Effect of 5-MTHF and Folic Acid Supplementation in Increasing Red Blood Cell Folate in Pregnant WomenRecruiting · Interventional · 100 enrolled · Dr. Soetomo General HospitalNCT06935630updated 2025-04-29
Frequently asked questions
- How does Levomefolate work?
- Mechanism-of-action class: Enzyme Interactions.
- What class of drug is Levomefolate?
- Levomefolate is classified as Enzyme Interactions, Cellular Activity Alteration.
- What are the brand names for Levomefolate?
- Levomefolate is marketed under brand names including Folixate.
Note. Data for
levomefolate is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.