Lutein

• STROVITE ® ONE is indicated to provide nutritional supplementation to support optimum vitamin and mineral levels.

• STROVITE ® ONE is contraindicated in patients with hypersensitivity to any of its components. Folic Acid is contraindicated in patients with untreated and uncomplicated pernicious anemia, and in those with anaphylactic sensitivity to folic acid.contraindicated

One caplet daily or as directed by a physician.

WARNING/PRECAUTIONS Vitamin D supplementation should be used with caution in those with hypercalcemia or conditions that may lead to hypercalcemia such as hyperparathyroidism and those who form calcium-containing kidney stones. High doses of vitamin D can lead to elevated levels of calcium that reside in the blood and soft tissues. Bone pain, high blood pressure, formation of kidney stones, renal failure, and increased risk of heart disease can occur. Folic acid, especially in doses above 0.1 mg daily, may obscure pernicious anemia, in that hematologic remission may occur while neurological manifestations remain progressive. The use of folic acid doses above 1 mg daily may precipitate or exacerbate the neurological damage of vitamin B12 deficiency. Avoid overdosage. Keep out of the reach of children.

Adverse reactions have been reported with specific vitamins and minerals, but generally at levels substantially higher than those in STROVITE ® ONE.

1. 1Emotional Distress719%
2. 2Pain719%
3. 3Anxiety616%
4. 4Anhedonia514%
5. 5Drug Ineffective514%
6. 6Back Pain411%
7. 7Dyspnoea411%
8. 8Economic Problem411%
9. 9Osteoporosis411%
10. 10Alopecia38.1%
11. 11Bone Density Decreased38.1%
12. 12Chronic Kidney Disease38.1%
13. 13Death38.1%
14. 14Depression38.1%
15. 15Dermatitis Atopic38.1%

Recent PubMed references pinned to Lutein as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Lutein Influences Cisplatin Sensitivity Through Differential Regulation of DNA Damage Response Genes in Breast Cancer Cells.
  Journal of biochemical and molecular toxicology · 2026 · Demirtas Korkmaz F, Duzgun Z, Cebi A, et al.
  PMID 42231618DOI 10.1002/jbt.70926
• Solvent-Free Oil-Based Extraction and Microencapsulation of Lutein from Marigold (Calendula officinalis).
  Molecules (Basel, Switzerland) · 2026 · Wieland A, Kurek MA
  PMID 42197203DOI 10.3390/molecules31101649
• Human milk-inspired medium- and long-chain triacylglycerol emulsions: A promising carrier for lutein with enhanced stability and digestibility.
  Food research international (Ottawa, Ont.) · 2026 · Yuan T, Gao X, Yang Y, et al.
  PMID 42169292DOI 10.1016/j.foodres.2026.119328
• Mechanisms of Cell Uptake and Transport of Xanthophylls in the Caco-2 Cell Model.
  Nutrients · 2026 · Wu F, Chen N, Peng Y, et al.
  PMID 42123990DOI 10.3390/nu18091389
• Lutein Modulates Stress-Responsive Signaling Pathways in THLE-2 Human Hepatocytes Under Intestinal Failure-Associated Liver Disease Conditions.
  Molecules (Basel, Switzerland) · 2026 · Żółnowska I, Krajka-Kuźniak V, Belka M, et al.
  PMID 42123779DOI 10.3390/molecules31091413
• Mitigating cryodamage in ram semen using lutein-loaded chitosan nanoparticles: Insights from antioxidant and apoptotic analyses.
  Cryobiology · 2026 · El-Raghi AA, Mohammed AK, Elmorsy EM, et al.
  PMID 42119398DOI 10.1016/j.cryobiol.2026.105637
• An in silico study of binding of new lutein esters to nuclear endocrine receptors.
  Food research international (Ottawa, Ont.) · 2026 · Vračko M, Albreht A
  PMID 42116501DOI 10.1016/j.foodres.2026.119262
• PpbHLH14.1-PpCCD4a regulatory module modulates lutein accumulation and peel colouration in pear (Pyrus pyrifolia).
  Plant physiology and biochemistry : PPB · 2026 · Zhang L, Cheng Y, Du W, et al.
  PMID 42096969DOI 10.1016/j.plaphy.2026.111352

The 10 most recently updated of 140 ClinicalTrials.gov registrations naming Lutein as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Yellow Potatoes and Carotenoids
  Recruiting · Interventional · 30 enrolled · University of Florida
  NCT07606001updated 2026-06-11
• Efficacy and Safety Safety of Nutritears® in Adults With Dry Eye Syndrome
  Completed · Interventional · 131 enrolled · Applied Science & Performance Institute
  NCT05481450updated 2026-06-04
• Study of the Macular Pigment by the Consumption of Corn With Strong Content in Zeaxanthine
  Terminated · Interventional · 9 enrolled · University Hospital, Bordeaux
  NCT02113254updated 2026-05-22
• Algal Lutein Against Decline of Intellectual Nimbleness
  Not yet recruiting · Interventional · 300 enrolled · Poznan University of Life Sciences
  NCT07600567updated 2026-05-20
• Sweet Corn and Carotenoids
  Active not recruiting · Interventional · 40 enrolled · University of Florida
  NCT06892444updated 2026-05-13
• Synergistic Activity of Human Milk Nutrients and Infant Cognition
  Recruiting · Interventional · 84 enrolled · University of North Carolina, Chapel Hill
  NCT03838536updated 2026-04-20
• Assessment of the Effects of a Daily Supplement 4Life Transfer Factor Vista Containing AREDS2 Formula on Skin Carotenoid Levels Using a Non-invasive Detection
  Completed · Interventional · 24 enrolled · 4Life Research, LLC
  NCT07513597updated 2026-04-07
• Lutein Iontophoresis in Intermediate AMD and Reticular Pseudodrusen - a Retrospective Study
  Completed · Observational · 30 enrolled · Mario Damiano Toro
  NCT07420361updated 2026-02-19
• A Clinical Study to Evaluate the Efficacy of a Nutritional Supplement to Improve Carotenoid Content as Measured by a Non-invasive Hyperspectral Absorption Device
  Completed · Interventional · 84 enrolled · Pharmanex
  NCT07380438updated 2026-02-02
• Effect of Carotenoids Supplementation on Visual Function in Chinese Subjects
  Not yet recruiting · Interventional · 220 enrolled · Zhongshan Ophthalmic Center, Sun Yat-sen University
  NCT06098677updated 2026-01-23

Frequently asked questions

What is Lutein used for?

According to FDA labeling, Lutein carries indications including: STROVITE ® ONE is indicated to provide nutritional supplementation to support optimum vitamin and mineral levels.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What are the brand names for Lutein?

Lutein is marketed under brand names including Macuvite with Lutein, MaxiVision Lutein Formula, Ocuvite, Ocuvite Lutein, PreserVision with Lutein.

What are the contraindications for Lutein?

Lutein labeling lists contraindications including: STROVITE ® ONE is contraindicated in patients with hypersensitivity to any of its components. Folic Acid is contraindicated in patients with untreated and uncomplicated pernicious anemia, and in those with anaphylactic sensitivity to folic acid.. Always consult the full prescribing information and a clinician.