Magnesium Ascorbate

Vitamin B 12 [ TREATMENT ]; FOLATE [ PREVENTION ]; OTHER [ SUPPLEMENTATION ];

• EnBrace HR ® is indicated in the TREATMENT of vitamin deficiency - specifically vitamin B 12 deficiency, and the PREVENTION of vitamin B 12 -cofactor deficiency, l-methylfolate. Requirements of vitamin B 9 and/or vitamin B 12 in excess of normal due to pregnancy can usually be met with oral supplementation.

​: The recommended dosage is one (1) capsule daily, preferably on an empty stomach. Dosage may be adjusted by a healthcare provider based on individual patient needs. As a general rule reticulocyte plasma count, folate and vitamin B 12 status must be obtained prior to treatment. Do not exceed the recommended dose. Call your medical practitioner about side effects. You may report side effects by calling (866) 280-5961.

Mild transient diarrhea, polycythemia vera, itching, transitory exanthema, feeling of swelling of entire body may occur with administration of vitamin B 12 . Allergic sensitization has been reported following both oral and parenteral administration of folic acid.

1. 1Abnormal Dreams114%
2. 2Agranulocytosis114%
3. 3Anxiety Disorder114%
4. 4Catheter Site Erythema114%
5. 5Catheter Site Irritation114%
6. 6Clostridium Difficile Infection114%
7. 7Cognitive Disorder114%
8. 8Drug Ineffective114%
9. 9Dysarthria114%
10. 10Foot Operation114%
11. 11Hallucination114%
12. 12Infusion Site Pain114%
13. 13Infusion Site Urticaria114%
14. 14Injection Site Pain114%
15. 15Insomnia114%

Recent PubMed references pinned to Magnesium Ascorbate as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Targeting oxidative stress pathways in epilepsy: mechanistic insights into the role of ascorbic acid.
  Molecular biology reports · 2026 · Desai M, Malik S, Singh A, et al.
  PMID 42240857DOI 10.1007/s11033-026-12077-2
• Dual-mechanism vitamin C delivery by polyethylene glycol-23 glyceryl distearate-based niosomes via SVCT2 induction and enhanced transdermal penetration.
  Drug delivery · 2026 · Miyoshi T, Keller BC, Nakagawa S, et al.
  PMID 42217232DOI 10.1080/10717544.2026.2681287
• Effect of calcium ascorbate and maltitol on calcium signaling and genes of cell wall and membrane synthesis in yeast under freeze-thaw cycle.
  Food microbiology · 2026 · Xie D, Zheng J, Zhao L, et al.
  PMID 42215203DOI 10.1016/j.fm.2026.105123
• Hemoglobin-assisted, ZIF-derived porous bimetallic FeCo/N-C nanozyme with high oxidase-like activity for colorimetric sensing.
  Mikrochimica acta · 2026 · Wang Z, Chen Y, Lin X, et al.
  PMID 42209727DOI 10.1007/s00604-026-08155-8
• Vitamin C mitigates early auditory cortical hyperexcitability and antioxidant imbalance induced by acute intermittent hypoxia.
  Experimental brain research · 2026 · Wu Y, Li T, Cao W, et al.
  PMID 42207332DOI 10.1007/s00221-026-07310-0
• A Randomized, Double-Blind, Placebo-Controlled Trial of an Ayurvedic Herbal Formulation and Vitamin C/E on Vascular Function in Patients with Cardiovascular Disease.
  Medicina (Kaunas, Lithuania) · 2026 · Salerno JW, Xu S, Rainforth M, et al.
  PMID 42195225DOI 10.3390/medicina62050972
• Investigation of Sevoflurane-Induced Apoptotic Damage in Human Cardiomyocytes and the Protective Efficacy of Ascorbic Acid.
  Medicina (Kaunas, Lithuania) · 2026 · Aydoğan E, Övey İS, Karahan O, et al.
  PMID 42195198DOI 10.3390/medicina62050945
• Catalytic Reduction of H(2)O(2) by Polyvinylpyrrolidone Nickel Oxide Nanozymatic Activity and Colorimetric Sensing of Ascorbic Acid.
  Biosensors · 2026 · Rambevha M, Chavalala R, Mashazi P, et al.
  PMID 42187495DOI 10.3390/bios16050299

The 10 most recently updated of 1,211 ClinicalTrials.gov registrations naming Magnesium Ascorbate as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• A 4-week Study Investigating Two Targeted Brightening Serum (A and B) Versus 4% Hydroquinone in Women With Mild to Severe Full-face Hyperpigmentation
  Completed · Interventional · 18 enrolled · Revision Skincare
  NCT07644871updated 2026-06-12
• FILLing Protocols for the Right Bladder Volume at the RIGHT Time (FILLRIGHT)
  Not yet recruiting · Interventional · 20 enrolled · University Hospital, Brest
  NCT07642570updated 2026-06-11
• Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery
  Completed · Phase 3 · Interventional · 995 enrolled · Centre Hospitalier Universitaire, Amiens
  NCT02390505updated 2026-06-11
• Effect of Magnesium-, Vitamin C- and Grape Seed Extract-Enriched Date Bars on Perceived Stress and Salivary Cortisol Levels in Young Women
  Active not recruiting · Interventional · 30 enrolled · K.G. Razumovsky Moscow State University of Technologies and Management
  NCT07585422updated 2026-06-10
• Oxalate Formation From Ascorbic Acid
  Active not recruiting · Interventional · 90 enrolled · University of Alabama at Birmingham
  NCT04603898updated 2026-06-09
• Urinary Vitamin C Loss in Diabetic Subjects
  Recruiting · Observational · 5,000 enrolled · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  NCT00071526updated 2026-06-08
• Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women
  Completed · Phase 1 · Interventional · 50 enrolled · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  NCT00862433updated 2026-06-08
• Evaluation of the Safety and Tolerability of a Brightening Treatment Paired With a Skincare Regimen
  Completed · Interventional · 11 enrolled · Revision Skincare
  NCT07501000updated 2026-06-05
• High Dose Ascorbic Acid (HDAA) in Patients With Plasma Cell Disorders
  Recruiting · Phase 1 · Interventional · 18 enrolled · University of Arkansas
  NCT06313502updated 2026-06-04
• Protect and Improve Cluster of Differentiation 4 (CD4) Cells and B Cells Lymphocytes
  Withdrawn · Phase 4 · Interventional · 0 enrolled · Trieu, Nguyen Thi, M.D.
  NCT04770701updated 2026-06-04

Frequently asked questions

How does Magnesium Ascorbate work?

Vitamin B 12 [ TREATMENT ]; FOLATE [ PREVENTION ]; OTHER [ SUPPLEMENTATION ];

What is Magnesium Ascorbate used for?

According to FDA labeling, Magnesium Ascorbate carries indications including: EnBrace HR ® is indicated in the TREATMENT of vitamin deficiency - specifically vitamin B 12 deficiency, and the PREVENTION of vitamin B 12 -cofactor deficiency, l-methylfolate. Requirements of vitamin B 9 and/or vitamin B 12 in excess of normal due to pregnancy can usually be met with oral supplementation.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.