Methionine

• Take 15 minutes before meals

DIRECTIONS Adults and children 12 years and older 20 drops in a little water, 2 times per day Children between 12 years and 6 years of age 10 drops in a little water, 2 times per day Children under 6 years 5 drops in a glass of water, 2 times per day

Stop use and ask doctor if symptoms persist more than 5 days. If pregnant or breast-feeding ask a health professional before use. Keep out of reach of children . In case of overdose, get medical help or contact a Poison Control Center right away. Contains ethyl alcohol 30%

• Jul 20, 1984NDANDA019018B Braun
• Aug 23, 1984NDANDA018931Baxter Hlthcare
• Sep 6, 1985NDANDA019398Otsuka Icu Medcl
• Oct 17, 1986NDANDA019492Otsuka Icu Medcl
• Dec 19, 1991NDANDA020041Otsuka Icu Medcl
• Dec 19, 1991NDANDA020015Otsuka Icu Medcl
• Mar 26, 1997NDANDA020678Baxter Hlthcare
• Sep 29, 1997NDANDA020734Baxter Hlthcare

1. 1Parenteral Nutrition Associated Liver Disease507.0%
2. 2Nausea456.3%
3. 3Pyrexia415.7%
4. 4Vomiting385.3%
5. 5Chills354.9%
6. 6Death354.9%
7. 7Dyspnoea304.2%
8. 8No Adverse Event304.2%
9. 9Diarrhoea263.6%
10. 10Asthenia243.3%
11. 11Palpitations233.2%
12. 12Pneumonia212.9%
13. 13Pruritus212.9%
14. 14Chest Discomfort202.8%
15. 15General Physical Health Deterioration182.5%

Recent PubMed references pinned to Methionine as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Effects of dietary methionine, betaine, and turmeric extract on growth performance, myogenic gene expression, serum protein profile, and intestinal histomorphology in broiler chickens.
  Tropical animal health and production · 2026 · Abdelzaher GM, Baloza SH, Khalifa OA, et al.
  PMID 42223732DOI 10.1007/s11250-026-05080-z
• Mutagenic Survey of Key Residues of NifB Involved in Radical SAM-Dependent Nitrogenase Cofactor Assembly.
  Chembiochem : a European journal of chemical biology · 2026 · Duffin C, Quechol R, Yang Y, et al.
  PMID 42218797DOI 10.1002/cbic.70400
• SeMet attenuates TBBPA-induced hepatocyte injury via inhibiting endoplasmic reticulum stress.
  Journal of environmental sciences (China) · 2026 · Xing P, Qian Y, Jiao Z, et al.
  PMID 42217894DOI 10.1016/j.jes.2025.09.055
• Methionine, Homocysteine, and Methylation Levels Predict Cognitive Decline in Alzheimer's Disease.
  CNS neuroscience & therapeutics · 2026 · Zhang X, Guan A, Li W, et al.
  PMID 42201257DOI 10.1002/cns.70954
• Effect of Branched-Chain Amino Acid Supplementation Alone or Combined With Tryptophan or Methionine on Appetite Control and Related Health Outcomes in Older Adults: Protocol for a Randomized Controlled Trial.
  JMIR research protocols · 2026 · Zhang S, Ribeiro R, Raubenheimer D, et al.
  PMID 42166751DOI 10.2196/82436
• Methionine Restriction Extends Yeast Lifespan by Activating Non-Nitrogen-Starvation-Induced Autophagy Through Limiting Methylation of Protein Phosphatase 2A.
  Aging cell · 2026 · Birmingham K, Arslanovic N, Grauer T, et al.
  PMID 42160763DOI 10.1111/acel.70550
• Sinefungin Biosynthesis Employs a B(12)-Dependent Radical S-Adenosyl-l-methionine Enzyme Catalyzing C-Adenosylation of Arginine.
  Journal of the American Chemical Society · 2026 · Ueno K, Ushimaru R, Yang Y, et al.
  PMID 42127262DOI 10.1021/jacs.6c05246
• Assessment of Protein Conformation via Diazirine-Promoted Oxidation of Methionine and Tryptophan Residues.
  Analytical chemistry · 2026 · Prertprawnon S, Neufeld SR, Borotto NB, et al.
  PMID 42117226DOI 10.1021/acs.analchem.5c08256

The 10 most recently updated of 210 ClinicalTrials.gov registrations naming Methionine as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors
  Recruiting · Early phase 1 · Interventional · 25 enrolled · University of California, Irvine
  NCT07628634updated 2026-06-05
• LAparoscopic Preventive PRErectal Mesh
  Recruiting · Interventional · 834 enrolled · University Hospital, Lille
  NCT03766048updated 2026-05-22
• A Phase I Trial of S-Adenosylmethionine (SAMe) for Chemoprevention of Colorectal Adenomas
  Not yet recruiting · Phase 1 · Interventional · 18 enrolled · Jun Gong, MD
  NCT07582003updated 2026-05-12
• Metabolic Availability in Older and Younger Men
  Completed · Interventional · 28 enrolled · Wageningen University
  NCT06332651updated 2026-05-07
• SLM + Axitinib for Clear Cell RCC
  Completed · Phase 1 · Phase 2 · Interventional · 45 enrolled · Mohammed Milhem
  NCT02535533updated 2026-05-06
• hCG Treatment for Rehabilitation From a TBI
  Not yet recruiting · Early phase 1 · Interventional · 50 enrolled · VA Office of Research and Development
  NCT07557615updated 2026-05-06
• SAMe in Prevention of Oxaliplatin-associated Liver Injury
  Not yet recruiting · Phase 2 · Interventional · 30 enrolled · Cedars-Sinai Medical Center
  NCT06258525updated 2026-05-06
• Dietary Interventions During Living Kidney Donations
  Recruiting · Interventional · 80 enrolled · University of Cologne
  NCT05709600updated 2026-04-30
• Dose-finding Study: Popliteal Sciatic Nerve Block in Patients Undergoing Diabetic Foot Surgery
  Active not recruiting · Interventional · 45 enrolled · Seoul National University Hospital
  NCT04981067updated 2026-04-30
• A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection
  Active not recruiting · Phase 2 · Interventional · 112 enrolled · St. Jude Children's Research Hospital
  NCT01419067updated 2026-04-29

Frequently asked questions

What is Methionine used for?

According to FDA labeling, Methionine carries indications including: Take 15 minutes before meals. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Methionine?

Methionine is classified as Antidotes.

What are the brand names for Methionine?

Methionine is marketed under brand names including Aminosyn 10%, Sulfite-Free, Aminosyn 3.5 % M, Sulfite Free, Aminosyn 8.5 % with Electrolytes, Sulfite-Free, Aminosyn 8.5%, Sulfite-Free, Aminosyn II 10 %, Aminosyn II 15%, Aminosyn II 8.5 % with Electrolytes, Sulfite-Free, Aminosyn II 8.5 %, Sulfite-Free.