Pancreatin
US-FDASourced from openFDA
GET
/api/v1/drug/pancreatinIndications
Sourced from openFDA- ■ children under 7 years of age: consult a doctor ■ take 1-2 tablet as symptoms accur, as directed by a doctor
Dosage & administration
Sourced from openFDAfor oral use
Warnings & precautions
Sourced from openFDAAsk a doctor before use if you have taking a prescription drug. Antacids may interact with certain prescription drugs. When using this product ■ Do not take more than 4 tablet in 24 hours ■ Do not use the maximum dosage for more than 2 weeks Keep out of reach of children
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
8 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Asthenia225%
- 2Febrile Neutropenia225%
- 3Pneumonia225%
- 4Accidental Poisoning113%
- 5Atrial Fibrillation113%
- 6Cardiac Failure113%
- 7Cholangitis113%
- 8Death113%
- 9Intentional Self-injury113%
- 10Malignant Neoplasm Progression113%
- 11Pancytopenia113%
- 12Peritonitis113%
- 13Pruritus113%
- 14Sepsis113%
Literature
Recent PubMed references pinned to Pancreatin as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Molecular characterization of porcine pancreatin and α-amylase highlights protein and peptide complexity impacting in vitro digestion assays.Food research international (Ottawa, Ont.) · 2026 · Spada V, De Caro S, Di Stasio L, et al.PMID 42169291DOI 10.1016/j.foodres.2026.119327
- Effect of Storage Duration on Amylase, Protease, and Lipase Activities in Ultrasound-Assisted Extracted Bovine Pancreatin.Molecules (Basel, Switzerland) · 2026 · Kenenbay G, Chomanov U, Zhumaliyeva G, et al.PMID 41900079DOI 10.3390/molecules31060980
- Prediction of human exposure and first-pass metabolism of the fungicide trifloxystrobin using an in vitro intestinal pancreatin and Caco-2/HT29-MTX model.Archives of toxicology · 2026 · Hallscheidt E, Bothe K, Hahn M, et al.PMID 41807794DOI 10.1007/s00204-026-04340-z
- Structural, quantitative, and functional characterization of N-glycans in porcine pancreatin extract, lipase, and α-amylase.Enzyme and microbial technology · 2026 · Moon C, Jeong CM, Park CS, et al.PMID 41713249DOI 10.1016/j.enzmictec.2026.110830
- Adjunctive pancreatin therapy enhances glycemic and metabolic outcomes in type 2 diabetes mellitus: the modifying role of exocrine pancreatic function.Diabetes research and clinical practice · 2025 · Koca N, Yalçın NPMID 41086950DOI 10.1016/j.diabres.2025.112943
- In vitro release of aflatoxin M1 during enzymatic digestion of milk proteins: evaluation and analysis.Journal of the science of food and agriculture · 2026 · Monter-Arciniega A, Cruz-Cansino NDS, Castañeda-Ovando A, et al.PMID 40944480DOI 10.1002/jsfa.70201
- Tannic acid regulates wheat starch digestibility via competitive inhibition of starch retrogradation and enzymatic activities of pancreatin and amyloglucosidase.International journal of biological macromolecules · 2025 · Duan S, Li CPMID 40484080DOI 10.1016/j.ijbiomac.2025.145045
- The effect of adding pancreatin to standard otilinium bromide and simethicone treatment in type 2 diabetes mellitus patients with irritable bowel syndrome.Scientific reports · 2024 · Karpuzcu HC, Turan Erdoğan B, Erdoğan Ç, et al.PMID 39433866DOI 10.1038/s41598-024-74694-w
Clinical trials
The 10 most recently updated of 88 ClinicalTrials.gov registrations naming Pancreatin as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic InsufficiencyRecruiting · Phase 4 · Interventional · 30 enrolled · Ohio State UniversityNCT06477159updated 2026-06-10
- Phase 2 Study to Assess the Safety and Efficacy of ANG003Recruiting · Phase 2 · Interventional · 113 enrolled · Anagram Therapeutics, Inc.NCT07450547updated 2026-06-10
- Efficay of Physical Activity Program in PCOS Females With Fatty Pancrease and Thyroid HypofunctionRecruiting · Interventional · 40 enrolled · Cairo UniversityNCT07591246updated 2026-05-15
- A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency.Not yet recruiting · Phase 2 · Interventional · 66 enrolled · Aimmune Nestlé Health Science US R&D, LLCNCT07559175updated 2026-04-30
- A Prospective Non-randomized Controlled Interventional Study on the Effect of Shouhui Tongbian Capsules Combined With Pancreatin Enteric-coated Capsules on Pancreatic Exocrine Function in Patients After Curative Resection for Pancreatic CancerNot yet recruiting · Phase 4 · Interventional · 80 enrolled · Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineNCT07557394updated 2026-04-29
- Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)Active not recruiting · Phase 1 · Phase 2 · Interventional · 17 enrolled · Memorial Sloan Kettering Cancer CenterNCT05642962updated 2026-02-25
- Pancreaze (Pancrelipase) for Patients With Pancreatic Adenocarcinoma With Cachexia and Exocrine Pancreatic InsufficiencyActive not recruiting · Phase 2 · Interventional · 36 enrolled · Andrew Hendifar, MDNCT04098237updated 2026-01-23
- A Study on the Changes of Glucose Metabolism and Exocrine Function in Patients With Chronic PancreatitisRecruiting · Early phase 1 · Interventional · 80 enrolled · Shanghai Changzheng HospitalNCT07314489updated 2026-01-02
- Effect of Enzyme Therapy on Protein Metabolism in Chronic PancreatitisCompleted · Interventional · 11 enrolled · Institut National de Recherche pour l'Agriculture, l'Alimentation et l'EnvironnementNCT01154608updated 2025-10-06
- Pancrelipase With Nutritional Supplement in Patients at Risk of Malnutrition (EFFORT-ENZO)Recruiting · Interventional · 20 enrolled · Philipp SchuetzNCT06826105updated 2025-09-30
Frequently asked questions
- What is Pancreatin used for?
- According to FDA labeling, Pancreatin carries indications including: ■ children under 7 years of age: consult a doctor ■ take 1-2 tablet as symptoms accur, as directed by a doctor. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
Note. Data for
pancreatin is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.