Cardiac Failure
67 drugs39,666 FAERS reportsMedDRA PT
GET
/api/v1/reaction/cardiac-failureReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D006333
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Source: U.S. National Library of Medicine — MeSH (Heart Failure)
Drugs reporting Cardiac Failure (67)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Cellulase113%
- 2Pancreatin113%
- 3Azurite111%
- 4Cornsilk111%
- 5Doxapram29.1%
- 6Eplerenone9567.7%
- 7Glutamate17.7%
- 8Xenon17.7%
- 9Streptozocin167.1%
- 10Aprocitentan17.1%
- 11Vericiguat657.0%
- 12Tafamidis1,0746.9%
- 13Landiolol56.2%
- 14Meglumine5285.9%
- 15Tolvaptan8025.8%
- 16Vadadustat135.3%
- 17Calcium Hydroxide15.3%
- 18Ivabradine3294.9%
- 19Daprodustat864.9%
- 20Milrinone124.4%
- 21Mexiletine184.3%
- 22Torsemide1,3654.3%
- 23Edoxaban2534.0%
- 24Sacubitril4,4763.9%
- 25Crovalimab33.7%
- 26Iloprost333.7%
- 27Coumarin63.7%
- 28Patisiran973.5%
- 29Metolazone3703.4%
- 30Spironolactone4,5483.3%
- 31Dopamine1243.3%
- 32Calfactant23.2%
- 33Factor X13.0%
- 34Clemastine403.0%
- 35Tirofiban853.0%
- 36Entrectinib472.9%
- 37Vutrisiran602.8%
- 38Perindopril1512.7%
- 39Evinacumab62.7%
- 40Furosemide9,9262.5%
- 41Febuxostat4122.5%
- 42Valsartan6,0592.5%
- 43Paricalcitol3482.5%
- 44Deferoxamine522.5%
- 45Sodium Zirconium Cyclosilicate842.5%
- 46Zirconium842.4%
- 47Miglitol222.4%
- 48Etelcalcetide662.3%
- 49Cangrelor92.3%
- 50Zanidatamab12.3%
- 51Relebactam22.2%
- 52Dronedarone2232.2%
- 53Idarucizumab312.2%
- 54Vonoprazan1452.2%
- 55Triheptanoin112.1%
- 56Lactobionate32.1%
- 57Alprostadil732.0%
- 58Belzutifan272.0%
- 59Pretomanid132.0%
- 60Dapagliflozin1,1332.0%
- 61Carfilzomib5482.0%
- 62Icodextrin5771.9%
- 63Mavacamten791.8%
- 64Epinastine201.8%
- 65Epirubicin1091.8%
- 66Romosozumab2011.6%
- 67Bisoprolol3,827—
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
- Atrial Fibrillation15 shared · 0.11
- Renal Impairment13 shared · 0.10
- Hepatic Function Abnormal8 shared · 0.09
- Cardiogenic Shock7 shared · 0.08
- Cardiac Failure Congestive7 shared · 0.08
- Oedema Peripheral10 shared · 0.08
- Gastrointestinal Haemorrhage7 shared · 0.07
- Cardiac Disorder6 shared · 0.07
- Myocardial Infarction7 shared · 0.06
- Cardio-respiratory Arrest6 shared · 0.06
Literature
Recent PubMed references pinned to Heart Failure as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Hyperkalemia in Heart Failure Hospitalizations: An Underreported Contributor to Poor Outcomes and Higher Costs in Brazil.Arquivos brasileiros de cardiologia · 2026 · Pecoits-Filho R, Rocha PT, Costa MCD, et al.PMID 42207122DOI 10.36660/abc.20250394
- Triglyceride-glucose index and subclinical left ventricular dysfunction across cardiovascular-kidney-metabolic syndrome stages: a 7-year retrospective cohort study.Frontiers in endocrinology · 2026 · Tsai KZ, Lin GM, Yun C, et al.PMID 42205253DOI 10.3389/fendo.2026.1783741
- Stem-Cell-Derived Biologic Ventricular Assist Tissue in Heart Failure.The New England journal of medicine · 2026 · Zimmermann WH, Ensminger S, Kutschka I, et al.PMID 42202318DOI 10.1056/NEJMoa2513525
- Hypertensive Acute Heart Failure: An Evidence Based Approach.Critical care nursing quarterly · 2026 · El Hussein MT, Homan A, Osuji C J, et al.PMID 42202154DOI 10.1097/CNQ.0000000000000611
- Implementing a Mobility Program for Pretransplant Patients With Femoral Intra-Aortic Balloon Pump: A Nurse-Led Initiative Quality Improvement Approach.Critical care nursing quarterly · 2026 · Velazquez MA, Andreas A, Chan A, et al.PMID 42202153DOI 10.1097/CNQ.0000000000000609
- Cardiac Lymphatic Dysfunction in Heart Failure: A New Paradigm for Congestion, Inflammation, and Therapy.Medical sciences (Basel, Switzerland) · 2026 · Epelde FPMID 42201058DOI 10.3390/medsci14020266
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.