Petrolatum
US-FDASourced from openFDA
GET
/api/v1/drug/petrolatumIndications
Sourced from openFDA- Uses temporarily protects minor: cuts, scrapes, burns. temporarily protects and helps relieve chapped or cracked skin and lips.
Dosage & administration
Sourced from openFDADirections Apply as needed.
Warnings & precautions
Sourced from openFDAFor external use only When using this product Do not get in eyes. Stop use and ask a doctor if condition worsens symptoms last more than 7 days or clear up and occur within a few days. Do not use on Deep or puncture wounds animal bites. serious burns Keep out of reach of children If swallowed, get medical help or contact a Poison Control Center right away.
Approval history
Sourced from openFDA- Feb 16, 2006NDANDA021026Mylan
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
3,351 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Eye Irritation35211%
- 2Eye Pain3319.9%
- 3Drug Ineffective2647.9%
- 4Vision Blurred2597.7%
- 5Ocular Hyperaemia2296.8%
- 6Dry Eye2156.4%
- 7Nausea1394.1%
- 8Diarrhoea1303.9%
- 9Foreign Body Sensation In Eyes1253.7%
- 10Off Label Use1233.7%
- 11Eye Pruritus1193.6%
- 12Rash1183.5%
- 13Headache1153.4%
- 14Lacrimation Increased1153.4%
- 15Pyrexia1153.4%
Literature
Recent PubMed references pinned to Petrolatum as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Combustion aerosols from mineral oil industrial fires: Physicochemical characterization and toxicity in bronchial epithelial cells at the air-liquid interface.Environmental pollution (Barking, Essex : 1987) · 2026 · Méausoone C, Rogez-Florent T, Castilla C, et al.PMID 42167524DOI 10.1016/j.envpol.2026.128396
- Impaired growth after immunization with a bivalent oil-adjuvanted vaccine occurs without detectable changes to aerobic capacity in juvenile rainbow trout.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2026 · Wallbom N, Khansari AR, Sandblom E, et al.PMID 42119917DOI 10.1016/j.cbpa.2026.112014
- A systematic evaluation of aluminium oxide (Alox) on mineral oil saturated hydrocarbons (MOSH) recovery and dietary exposure from vegetable oils in China.Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment · 2026 · Zhang M, Ho XL, Wang Y, et al.PMID 41979326DOI 10.1080/19440049.2026.2644477
- Influence of Hydrophilic Interaction on Polyglycerol Ester Emulsifier at Oil-polyol nterface: Interfacial Adsorption Behavior and Its Relationship with Emulsification Effect.Journal of oleo science · 2026 · Zhang W, Fu Y, Zhou C, et al.PMID 41922202DOI 10.5650/jos.ess25181
- Sustainable treatment of banana leaves for phytosanitary applications: impact, spreading, and impregnation of mineral oil.Pest management science · 2026 · Alayan A, Boyer S, Verdeil JL, et al.PMID 41705286DOI 10.1002/ps.70660
- Petrolatum-based ointment application induces swelling of the PRESERFLO Microshunt.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026 · Tomita R, Inooka T, Kajita T, et al.PMID 41528468DOI 10.1007/s00417-025-07075-2
- Influences of oils on the persistence and recovery of DNA.Journal of forensic sciences · 2026 · Kaesler T, Linacre A, Kirkbride KP, et al.PMID 41521515DOI 10.1111/1556-4029.70249
- Balancing efficacy and resistance: oils vs. synthetic acaricides in the control of Panonychus citri.Experimental & applied acarology · 2025 · Qayyoum MA, Mobarak SH, Khan BS, et al.PMID 41372711DOI 10.1007/s10493-025-01098-4
Clinical trials
The 10 most recently updated of 311 ClinicalTrials.gov registrations naming Petrolatum as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Efficacy and Safety of 0.25% Timolol Gel in Enhancing Full Thickness Skin Grafts Healing and Cosmetic OutcomesTerminated · Phase 2 · Phase 3 · Interventional · 10 enrolled · Brigham and Women's HospitalNCT03579160updated 2026-06-09
- Effect of Foot Massage on Pain and Analgesic Consumption in Total Knee ProsthesisRecruiting · Interventional · 60 enrolled · Alev KeskinNCT07126340updated 2026-06-09
- Using a Contact Dermatitis Model With Biologic Medications to Study Skin InflammationActive not recruiting · Phase 2 · Phase 3 · Interventional · 45 enrolled · Wei-Che KoNCT05535738updated 2026-06-09
- Paraffin Oil for Preventing Tourniquet-Related Skin Lesions in Upper Extremity SurgeryRecruiting · Interventional · 90 enrolled · Istanbul Medipol University HospitalNCT07523958updated 2026-06-04
- Dermocosmetic Evaluation of Propolis Ointments in Atopic-Prone Dry SkinActive not recruiting · Interventional · 30 enrolled · Manara UniversityNCT07618234updated 2026-06-01
- Integrated Neuromuscular Inhibition Technique Versus Instrument-Assisted Soft Tissue Mobilization On Neck Disability, Endurance, and Proprioception Of Nonspecific Chronic Neck PainNot yet recruiting · Interventional · 60 enrolled · Cairo UniversityNCT07599631updated 2026-05-20
- A Between Patient Study of Plurogel® Compared to Standard Topical Dressing in Burn InjuriesRecruiting · Phase 1 · Phase 2 · Interventional · 25 enrolled · University of ManitobaNCT05000983updated 2026-05-14
- A Study of Plurogel® Compared to Standard Topical Dressing in Burn InjuriesRecruiting · Phase 1 · Phase 2 · Interventional · 20 enrolled · University of ManitobaNCT04893863updated 2026-05-14
- Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open WoundsCompleted · Phase 2 · Phase 3 · Interventional · 87 enrolled · Brigham and Women's HospitalNCT03452072updated 2026-05-14
- Phase III Efficacy and Safety Study of Miconazole Oil for OtomycosisCompleted · Phase 3 · Interventional · 112 enrolled · Hill Dermaceuticals, Inc.NCT05660382updated 2026-05-12
Frequently asked questions
- What is Petrolatum used for?
- According to FDA labeling, Petrolatum carries indications including: Uses temporarily protects minor: cuts, scrapes, burns. temporarily protects and helps relieve chapped or cracked skin and lips.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What are the brand names for Petrolatum?
- Petrolatum is marketed under brand names including A+D Original, Aloe Vesta Protective Barrier, Altalube, Anbesol Cold Sore Therapy, Aquaphor, Balmex Ointment, Baza Clear, Boroleum.
Note. Data for
petrolatum is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.