Polysorbate 80

• Uses relieves redness of the eye due to minor eye irritations temporarily relieves burning and irritation due to dryness of the eye for protection against further irritation

Directions put 1 or 2 drops in the affected eye(s) up to 4 times daily tightly snap on cap to seal Other information do not store above 25°C (77°F)

When using this product do not touch top of container to any surface to avoid contamination replace cap after each use do not use if solution changes color or becomes cloudy overuse may cause more eye redness pupils may become enlarged temporarily remove contact lenses before using

1. 1Eye Irritation21920%
2. 2Eye Pain21720%
3. 3Cataract16715%
4. 4Vision Blurred11410%
5. 5Dry Eye1089.8%
6. 6Drug Ineffective988.9%
7. 7Ocular Hyperaemia888.0%
8. 8Photophobia595.4%
9. 9Off Label Use585.3%
10. 10Visual Impairment544.9%
11. 11Foreign Body Sensation In Eyes484.4%
12. 12Lacrimation Increased484.4%
13. 13Macular Degeneration444.0%
14. 14Eye Discharge423.8%
15. 15Headache413.7%

Recent PubMed references pinned to Polysorbate 80 as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• In situ biotransformation of synthetic glutamate to γ-amino butyric acid by an auxotrophic Lactococcus lactis in polysorbate-mediated thermoaerobic process.
  Biodegradation · 2026 · Ali S, Arif K, Khan QF, et al.
  PMID 42174258DOI 10.1007/s10532-026-10313-x
• Ex Vivo Characterization and In Vivo Nasal Delivery of Ropinirole-Loaded PEO-b-PCL/Tween 80/β-Cyclodextrin Systems in C57BL/6J Mice.
  Molecules (Basel, Switzerland) · 2026 · Saitani EM, Papakyriakopoulou P, Balafas E, et al.
  PMID 42123771DOI 10.3390/molecules31091405
• [STIKO Recommendation: MF59-Adjuvanted Influenza Vaccine for Individuals ≥ 60 Years of Age].
  Deutsche medizinische Wochenschrift (1946) · 2026 · Prelog M, Gärtner B, Leischker A, et al.
  PMID 42081914DOI 10.1055/a-2812-2784
• Cost-effectiveness of vaccination of older adults with an MF59®-adjuvanted quadrivalent influenza vaccine compared to standard-dose and high-dose vaccines in South Korea and Taiwan.
  Vaccine · 2026 · Hsieh SM, Choi MJ, Chen YC, et al.
  PMID 41962206DOI 10.1016/j.vaccine.2026.128533
• Molecular mechanisms of interface interactions in Pickering emulsions co-stabilized by β-cyclodextrins and Tween 60.
  Food chemistry · 2026 · Huang J, Zhang Y, Li T, et al.
  PMID 41916218DOI 10.1016/j.foodchem.2026.148992
• AS01(B)-, MF59-, and alum-based adjuvants and HIV vaccine immunogenicity: a post-hoc cross-protocol comparison of results from HVTN 100, 107, 120, and 702.
  Frontiers in immunology · 2026 · Menezes F, Chen S, Grunenberg N, et al.
  PMID 41909709DOI 10.3389/fimmu.2026.1768201
• Aggregation of monoclonal and bispecific antibodies during pneumatic tube transport of IV bags in a hospital: Mitigation by polysorbate 80, poloxamer 188, and headspace removal.
  Journal of pharmaceutical sciences · 2026 · Parnian P, Medina AM, Lopez NG, et al.
  PMID 41905654DOI 10.1016/j.xphs.2026.104264
• Immunogenicity and safety of MF59-adjuvanted H5N1 pandemic influenza vaccine in healthy infants and children: a phase 2 randomized, observer-blind, multicenter study.
  Vaccine · 2026 · Põder A, Trinidad-Aseron M, Van Twuijver E, et al.
  PMID 41895156DOI 10.1016/j.vaccine.2026.128504

The 10 most recently updated of 214 ClinicalTrials.gov registrations naming Polysorbate 80 as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
  Recruiting · Phase 2 · Phase 3 · Interventional · 2,250 enrolled · Global Coalition for Adaptive Research
  NCT03970447updated 2026-06-12
• Impact of Treatment With Rituximab on the Progression of Humoral Acute Rejection After Renal Transplantation
  Completed · Phase 3 · Interventional · 40 enrolled · University Hospital, Tours
  NCT01350882updated 2026-06-12
• Safety and Immunogenicity of an Inactivated West Nile Virus Vaccine in Healthy Adults
  Active not recruiting · Phase 1 · Interventional · 30 enrolled · National Institute of Allergy and Infectious Diseases (NIAID)
  NCT06745921updated 2026-06-12
• Precision Alemtuzumab Dosing for Allogeneic Hematopoietic Cell Transplantation
  Recruiting · Phase 2 · Interventional · 60 enrolled · Children's Hospital Medical Center, Cincinnati
  NCT05501756updated 2026-06-12
• Effect of Metformin, a Drug Used to Treat Diabetes, vs Placebo
  Active not recruiting · Phase 4 · Interventional · 150 enrolled · University of California, Los Angeles
  NCT05949008updated 2026-06-08
• Study of Intravenous ZMA001 in Healthy Subjects
  Recruiting · Phase 1 · Interventional · 96 enrolled · National Heart, Lung, and Blood Institute (NHLBI)
  NCT05967299updated 2026-06-05
• Assessment of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a New Formulation of Inclisiran Containing Polysorbate 80 Compared to the Currently Marketed Formulation
  Not yet recruiting · Phase 1 · Interventional · 120 enrolled · Novartis Pharmaceuticals
  NCT07626281updated 2026-06-04
• Retrospective Kinetic Safety Evaluation of an Intravenous Micellar Excipient Platform
  Not yet recruiting · Observational · 625 enrolled · PICO IV, Inc.
  NCT07609069updated 2026-05-29
• Evaluating the Efficacy and Safety of Lecanemab in Alzheimer's Disease Through Multi-omics Approachs
  Recruiting · Phase 4 · Interventional · 200 enrolled · First Affiliated Hospital of Wenzhou Medical University
  NCT07604896updated 2026-05-22
• Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free.
  Recruiting · Phase 3 · Interventional · 129 enrolled · Fundación GECP
  NCT06431633updated 2026-05-18

Frequently asked questions

What is Polysorbate 80 used for?

According to FDA labeling, Polysorbate 80 carries indications including: Uses relieves redness of the eye due to minor eye irritations temporarily relieves burning and irritation due to dryness of the eye for protection against further irritation. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What are the brand names for Polysorbate 80?

Polysorbate 80 is marketed under brand names including Viva-Drops Lubricating Eye Drops.