Potassium Iodide
GET
/api/v1/drug/potassium-iodideMechanism of action
Sourced from openFDAMechanism-of-action class: Unknown Cellular or Molecular Interaction.
Indications
Sourced from openFDA- Frontal Sinus Pain With Runny Nose, Worse At Night*
Dosage & administration
Sourced from openFDAAdults and children: At the onset of symptoms, dissolve 5 pellets under the tongue 3 times a day until symptoms are relieved or as directed by a doctor.
Approval history
Sourced from openFDA- Oct 14, 1982NDANDA018664Anbex
- Sep 10, 2002ANDAANDA076350Btg Intl
- Mar 24, 2016ANDAANDA206211Mission Pharmacal
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
2,070 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Diarrhoea31115%
- 2Fatigue28614%
- 3Dyspnoea27813%
- 4Headache27513%
- 5Nausea27013%
- 6Dizziness26513%
- 7Fall26113%
- 8Sepsis25712%
- 9Arthralgia25612%
- 10Insomnia25412%
- 11Haemorrhagic Stroke25312%
- 12Cough24312%
- 13Tachycardia24212%
- 14Cardio-respiratory Arrest23912%
- 15Asthenia23711%
Literature
Recent PubMed references pinned to Potassium Iodide as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Pre-Treatment With Potassium Iodide and Higher Radioiodine Dose Are the Risk Factors of Mid-to-Late-Phase Transient Thyrotoxicosis Following Radioiodine Therapy for Graves' Disease in Japanese Patients: A Retrospective Cohort Study.Clinical endocrinology · 2026 · Matsuda E, Osaki Y, Maruo K, et al.PMID 41491627DOI 10.1111/cen.70093
- How to discontinue potassium iodide in combined therapy with methimazole for initial treatment of Graves' disease.Endocrine journal · 2026 · Murakami T, Higaki N, Nishijima Y, et al.PMID 41443837DOI 10.1507/endocrj.EJ25-0204
- Improvement of antibacterial potency of riboflavin mediated photodynamic therapy by potassium iodide against Aggregatibacter actinomycetemcomitans biofilm formed on orthodontic miniscrews: An in vitro study.Photodiagnosis and photodynamic therapy · 2025 · Jafarieh D, Jafarieh R, Bahrami R, et al.PMID 41183698DOI 10.1016/j.pdpdt.2025.105268
- Integrated Stable Isotope Tracing and Acidified Potassium Iodide Reduction (SIT-APIR) Method to Determine Microbial Nitrification Rates across Environments.Analytical chemistry · 2025 · Wu J, Ma Y, Li X, et al.PMID 41108729DOI 10.1021/acs.analchem.5c02850
- 9H-carbazole derivatives from a Streptomyces species under potassium iodide stress and their anti-inflammatory properties.Archives of pharmacal research · 2025 · Yan P, Liu Y, Liu J, et al.PMID 40750755DOI 10.1007/s12272-025-01556-y
- Effect of Silver Diamine Fluoride and Potassium Iodide Application on the Microhardness and Shear Bond Strength of Resin Composite to Enamel and Dentin - An In vitro Study.Indian journal of dental research : official publication of Indian Society for Dental Research · 2025 · Bhardwaj S, Kaur H, Choudhary R, et al.PMID 40657979DOI 10.4103/ijdr.ijdr_515_23
- Effect of Potassium Iodide, Bleaching, and Microabrasion on the Colour of Silver Diamine Fluoride Stained Remineralised Caries Lesions.Oral health & preventive dentistry · 2025 · Al-Angari SSPMID 40613253DOI 10.3290/j.ohpd.c_2107
- Potassium Iodide Induces Apoptosis in Salivary Gland Cancer Cells.International journal of molecular sciences · 2025 · Skrypnyk M, Yatsenko T, Riabets O, et al.PMID 40508009DOI 10.3390/ijms26115199
Clinical trials
The 10 most recently updated of 94 ClinicalTrials.gov registrations naming Potassium Iodide as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Cross-Sectional and Longitudinal Studies of "Pre-Diabetes" in the Pima IndiansCompleted · Observational · 1,759 enrolled · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT00340132updated 2026-06-03
- A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1 Study)Recruiting · Interventional · 20 enrolled · Aqua Medical, Inc.NCT07355270updated 2026-04-30
- Comparison of the Clinical Effects of Open, Closed, and Semi-close Hemorrhoidectomy.Not yet recruiting · Interventional · 378 enrolled · The Affiliated Hospital of Putian UniversityNCT07196865updated 2026-03-04
- Traditional vs. Minimally Invasive Decay Treatments in Primary Molars: An 18-month Split-mouth Randomized StudyCompleted · Interventional · 60 enrolled · TC Erciyes UniversityNCT07447583updated 2026-03-03
- Preoperative Lugol's Solution in Graves' Disease and Toxic Nodular GoiterRecruiting · Phase 3 · Interventional · 182 enrolled · Jan CalissendorffNCT04856488updated 2026-02-10
- 131I-Omburtamab, in Recurrent Medulloblastoma and EpendymomaActive not recruiting · Phase 2 · Interventional · 62 enrolled · Pediatric Brain Tumor ConsortiumNCT04743661updated 2026-02-05
- Chemo Brain Prehab ProjectNot yet recruiting · Interventional · 86 enrolled · Dr. Chris GaffneyNCT07341217updated 2026-01-14
- MIBG for Refractory Neuroblastoma and PheochromocytomaCompleted · Interventional · 15 enrolled · Masonic Cancer Center, University of MinnesotaNCT01850888updated 2025-12-18
- CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)Recruiting · Phase 4 · Interventional · 72 enrolled · University of Missouri-ColumbiaNCT05846399updated 2025-10-15
- Evaluation of a Differentiated Point-of-care Active Case Finding & Management Model to Eliminate Mother-to-Child Transmission of HIV in MalawiRecruiting · Interventional · 2,426 enrolled · University of North Carolina, Chapel HillNCT06493357updated 2025-09-26
Frequently asked questions
- How does Potassium Iodide work?
- Mechanism-of-action class: Unknown Cellular or Molecular Interaction.
- What is Potassium Iodide used for?
- According to FDA labeling, Potassium Iodide carries indications including: Frontal Sinus Pain With Runny Nose, Worse At Night*. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Potassium Iodide?
- Potassium Iodide is classified as Antidotes, Expectorants, Other ophthalmologicals, Unknown Cellular or Molecular Interaction, Decreased Respiratory Secretion Viscosity, Decreased Thyroid Hormone Secretion, Increased Respiratory Secretions, Increased Thyroid Hormone Iodination, Unknown Physiological Effect.
- What are the brand names for Potassium Iodide?
- Potassium Iodide is marketed under brand names including Iosat, Lactocal, SSKI brand of Potassium Iodide, ThyroSafe, ThyroShield, Vitafol-One.
Note. Data for
potassium-iodide is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.