Pyridoxal
US-FDASourced from openFDA
GET
/api/v1/drug/pyridoxalIndications
Sourced from openFDA- Prenatal and Postnatal prescriptive Folic Acid
Dosage & administration
Sourced from openFDAUsual adult dose is 1 tablet once or twice daily or as prescribed by a licensed practitioner.
Warnings & precautions
Sourced from openFDAWARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under age 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or Poison Control Center immediately.
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
7 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Abnormal Dreams114%
- 2Agranulocytosis114%
- 3Anxiety Disorder114%
- 4Catheter Site Erythema114%
- 5Catheter Site Irritation114%
- 6Clostridium Difficile Infection114%
- 7Cognitive Disorder114%
- 8Drug Ineffective114%
- 9Dysarthria114%
- 10Foot Operation114%
- 11Hallucination114%
- 12Infusion Site Pain114%
- 13Infusion Site Urticaria114%
- 14Injection Site Pain114%
- 15Insomnia114%
Literature
Recent PubMed references pinned to Pyridoxal as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Potential Role of Vitamin B6 as an Antioxidant via Pyridoxal-5'-Phosphate-Dependent Metabolic Pathways and Subsequent Activation of Nrf2 Signaling.Nutrients · 2026 · Kato N, Yang Y, Khedara A, et al.PMID 42196957DOI 10.3390/nu18101499
- A Nonenzymatic Analogue of the Biosynthesis of Pyridoxal Vitamers.Journal of the American Chemical Society · 2026 · Nogal N, Basar AB, Minic Z, et al.PMID 42171396DOI 10.1021/jacs.6c01677
- Dimerization of MilM Is Essential for Catalyzing the Pyridoxal-5'-phosphate (PLP)-Dependent Cγ-Hydroxylation of l-Arginine during Mildiomycin Biosynthesis.Biochemistry · 2026 · Das S, Naik Y, Mishra U, et al.PMID 42136426DOI 10.1021/acs.biochem.6c00271
- Tumor suppressor function of SHMT in a Drosophila Ras(V12)Dlg(RNAi) model: DNA damage and synergistic gene-nutrient interaction with PLP.Cell death & disease · 2026 · Angioli C, Ferriero A, Pilesi E, et al.PMID 41888118DOI 10.1038/s41419-026-08602-7
- Mutational analyses reveal PLP-independent functions at PipY, the cyanobacterial paradigm for pyridoxal-phosphate binding proteins.Scientific reports · 2026 · Llop A, Tremiño L, Contreras A, et al.PMID 41820517DOI 10.1038/s41598-026-43837-6
- Pyridoxal 5'-Phosphate-Dependent Enzymatic Decarboxylative Annulation.Journal of the American Chemical Society · 2026 · Chai W, Luo S, Xi W, et al.PMID 41769737DOI 10.1021/jacs.5c20979
- Association Between Serum Pyridoxal 5'-Phosphate and Frailty Risk in Community-Dwelling Older Japanese Adults.Geriatrics & gerontology international · 2026 · Ohta M, Kaimoto K, Makizako H, et al.PMID 41709843DOI 10.1111/ggi.70412
- The Pyridoxal-5'-Phosphate-Dependent Enzymes of Mycobacterium tuberculosis.ACS infectious diseases · 2026 · Peracchi A, Baker BPMID 41616277DOI 10.1021/acsinfecdis.5c00996
Clinical trials
The 10 most recently updated of 354 ClinicalTrials.gov registrations naming Pyridoxal as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary TuberculosisRecruiting · Phase 3 · Interventional · 150 enrolled · National University Hospital, SingaporeNCT05473520updated 2026-06-09
- Composition for Treating Uterine Fibroid (SB-UF)Completed · Phase 4 · Interventional · 66 enrolled · Trieu, Nguyen Thi, M.D.NCT04762316updated 2026-06-08
- Immune-Mitochondrial Correction in Military RecruitsNot yet recruiting · Interventional · 200 enrolled · MIPO ClinicNCT07622147updated 2026-06-02
- Adjunctive Doxycycline for Central Nervous System TuberculosisRecruiting · Phase 2 · Interventional · 200 enrolled · National University Hospital, SingaporeNCT06446245updated 2026-06-01
- Study of Limited Versus Continuous Isoniazid Tuberculosis Preventive Therapy in HIV-infected Persons in BotswanaCompleted · Phase 4 · Interventional · 1,995 enrolled · Centers for Disease Control and PreventionNCT00164281updated 2026-05-27
- Vitamin B Complex for Inferior Alveolar Nerve Paresthesia RecoveryNot yet recruiting · Phase 4 · Interventional · 50 enrolled · University of Sao PauloNCT07592897updated 2026-05-20
- Impact of a Novel Functional Snack on Perimenopausal Symptoms and Well-beingRecruiting · Interventional · 20 enrolled · King's College LondonNCT07599930updated 2026-05-20
- Effect of a Food Intervention With a Prebiotic Alone or Combined With B-vitamins on Gut Microbiota Diversity, Inflammation and Mental Health Outcomes in Older Adults (GutFood)Recruiting · Interventional · 84 enrolled · University of UlsterNCT07592975updated 2026-05-18
- Effects of Vitamin D, Epigallocatechin Gallate, Vitamin B6, and D-Chiro-inositol Combination on Uterine FibroidsCompleted · Interventional · 108 enrolled · Universita di VeronaNCT05409872updated 2026-05-05
- B6 Administration for Levetiracetam-Associated Neurobehavioral Changes and EpilepsyNot yet recruiting · Interventional · 50 enrolled · Duke UniversityNCT07271966updated 2026-05-05
Frequently asked questions
- What is Pyridoxal used for?
- According to FDA labeling, Pyridoxal carries indications including: Prenatal and Postnatal prescriptive Folic Acid. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
Note. Data for
pyridoxal is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.