Skatole

• Take 15 minutes before meals

DIRECTIONS Adults and children 12 years and older 20 drops in a little water, 2 times per day Children between 12 years and 6 years of age 10 drops in a little water, 2 times per day Children under 6 years 5 drops in a glass of water, consult a physician

Stop use and ask doctor if symptoms persist more than 5 days. If pregnant or breast-feeding ask a health professional before use. Keep out of reach of children . In case of overdose, get medical help or contact a Poison Control Center right away. Contains ethyl alcohol 30%

1. 1Fatigue1389.1%
2. 2Nausea1228.1%
3. 3Dizziness1067.0%
4. 4Pain996.5%
5. 5Diarrhoea976.4%
6. 6Headache976.4%
7. 7Arthralgia865.7%
8. 8Drug Ineffective845.5%
9. 9Dyspnoea785.2%
10. 10Pain In Extremity734.8%
11. 11Pruritus684.5%
12. 12Asthenia664.4%
13. 13Vomiting634.2%
14. 14Insomnia604.0%
15. 15Rash563.7%

Recent PubMed references pinned to Skatole as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Decoding skatole: A comprehensive review on biosynthesis, metabolism, and mitigation in livestock production.
  Bioresource technology · 2026 · Zhang M, Liao X, Wang F, et al.
  PMID 41887418DOI 10.1016/j.biortech.2026.134491
• A novel and evolutionarily distinct flavoprotein monooxygenase drives skatole degradation in Rhodococcus.
  Applied and environmental microbiology · 2026 · Meng N, Li G, Zhang J, et al.
  PMID 41879300DOI 10.1128/aem.00228-26
• Effects of Saccharomyces cerevisiae on the regulation of skatole, microorganisms, and tryptophan metabolites in vitro fermentation of pig.
  Microbiology spectrum · 2026 · Gao X, Zhang S, Ge S, et al.
  PMID 41757950DOI 10.1128/spectrum.03292-25
• Indole-3-Acetic Acid as a Putative Selective AhR Modulator Counteracts Skatole-Induced Dual-Hit Toxicity in Colorectal Cancer Cells.
  Toxins · 2026 · Takei C, Shimizu H
  PMID 41745764DOI 10.3390/toxins18020098
• Nutty-flavour compound 3-methylbutanal production in milk by Lactococcus cremoris: biosynthesis pathway and role of pyruvate dehydrogenase.
  The Journal of dairy research · 2026 · Hayashizaki N, Ogura A, Maeda H, et al.
  PMID 41549732DOI 10.1017/S0022029925101957
• Managing Boar Taint: Issues, Prevention Strategies, and Detection Methods.
  Animal science journal = Nihon chikusan Gakkaiho · 2025 · Pereira-Pinto R, Moreira O, Vaz-Velho M, et al.
  PMID 40804789DOI 10.1111/asj.70090
• Effect of intranasal administration of Erigeron annuus and Carthamus tinctorius extracts in a rat model of olfactory dysfunction induced by 3-methylindole.
  PloS one · 2025 · Jeong M, Kwon H, Kim Y, et al.
  PMID 40493549DOI 10.1371/journal.pone.0325429
• Genetic investigations into the use of sensory evaluation: the case of boar taint discrimination in Pietrain sired crossbreds.
  Journal of animal science · 2025 · Markey A, Groβe-Brinkhaus C, Mörlein D, et al.
  PMID 39718970DOI 10.1093/jas/skae389

The 2 most recently updated of 2 ClinicalTrials.gov registrations naming Skatole as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• I2PETHV - Imidazoline2 Binding Site in Healthy Volunteers
  Completed · Early phase 1 · Interventional · 20 enrolled · Imperial College London
  NCT02323217updated 2021-11-15
• I2PETPG - Imidazoline2 Binding Sites in a Group of Participants Diagnosed With AD
  Terminated · Early phase 1 · Interventional · 2 enrolled · Imperial College London
  NCT02874820updated 2020-08-27

Frequently asked questions

What is Skatole used for?

According to FDA labeling, Skatole carries indications including: Take 15 minutes before meals. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.