Sodium Iodide
GET
/api/v1/drug/sodium-iodideMechanism of action
Sourced from openFDAMechanism-of-action classes: Physiochemical Activity; Unknown Cellular or Molecular Interaction.
Indications
Sourced from openFDA- First aid to help prevent infection in minor cuts, scrapes, and burns.
Dosage & administration
Sourced from openFDAClearn the affected area apply a small amount to the affected area 1 to 3 times daily. May be covered with sterile bandage. If bandaged let dry first.
Warnings & precautions
Sourced from openFDAFor external use only. Flammable, keep away from fire and flame
Approval history
Sourced from openFDA- May 27, 1982NDANDA018671Cardinal Health 418
- Feb 28, 1989ANDAANDA071910Curium
- Feb 28, 1989ANDAANDA071909Curium
- Jan 24, 2003NDANDA021305Jubilant
- Feb 5, 2020ANDAANDA209166Intl Isotopes
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
1,117 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Hypothyroidism40236%
- 2Endocrine Ophthalmopathy454.0%
- 3Hyperthyroidism312.8%
- 4Treatment Failure302.7%
- 5Abortion Spontaneous262.3%
- 6Nausea262.3%
- 7Acute Myeloid Leukaemia242.1%
- 8Dacryostenosis Acquired242.1%
- 9Drug Ineffective242.1%
- 10Maternal Exposure Before Pregnancy222.0%
- 11Parathyroid Tumour Benign222.0%
- 12Lacrimation Increased211.9%
- 13Vomiting201.8%
- 14Hyperparathyroidism191.7%
- 15Sialoadenitis181.6%
Literature
Recent PubMed references pinned to Sodium Iodide as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Development of PDMS Films Containing Thiamine Bromide and Sodium Iodide: Part 1-Matrix Characterisation and In Vitro Release.Molecules (Basel, Switzerland) · 2026 · Farmazyan Z, Avagyan N, Topuzyan V, et al.PMID 42197141DOI 10.3390/molecules31101588
- The impact of NaI(Tl) crystal hydration on gamma camera spectral response and image uniformity.Journal of applied clinical medical physics · 2025 · Eliason G, Silosky MSPMID 40841187DOI 10.1002/acm2.70218
- ACR-ACNM-ARS-SNMMI-SPR Practice Parameter for Treatment of Benign and Malignant Thyroid Disease With I-131 Sodium Iodide.American journal of clinical oncology · 2026 · Trout AT, Boike TP, Avram AM, et al.PMID 40694360DOI 10.1097/COC.0000000000001239
- Real-world Data on Intermediate-risk Differentiated Thyroid Cancer Biochemical Response to 3700 or 5550 MBq of [(131)I]Sodium Iodide.Current radiopharmaceuticals · 2025 · Machado DM, Bulzico DA, Fontes LF, et al.PMID 40329734DOI 10.2174/0118744710374569250415095218
- Monte Carlo simulations of 5/8'' NaI gamma camera detector response in radiological emergency preparedness.Journal of radiological protection : official journal of the Society for Radiological Protection · 2025 · Hjellström M, Isaksson MPMID 40300612DOI 10.1088/1361-6498/add1e6
- Application of gamma spectrum analysis techniques for natural radioactivity measurements using NaI(Tl) detector.Environmental monitoring and assessment · 2025 · Naeem N, Sohail M, Ahmed R, et al.PMID 40100443DOI 10.1007/s10661-025-13893-y
- Experimental and GEANT4 simulated FEPE of NaI(Tl) detector for linear sources.Biomedical physics & engineering express · 2025 · Mansoor S, Malik AH, Satti KH, et al.PMID 39869945DOI 10.1088/2057-1976/adaec8
- Depletion of iodide in ageing aerosols and the role of humidity: A case study of mixed sodium iodide-malonic acid aerosol.Chemosphere · 2024 · Saha S, Pandiyathuray MPMID 39332584DOI 10.1016/j.chemosphere.2024.143411
Clinical trials
The 10 most recently updated of 111 ClinicalTrials.gov registrations naming Sodium Iodide as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- 177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid CancerNot yet recruiting · Phase 1 · Phase 2 · Interventional · 18 enrolled · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT06991738updated 2026-06-12
- Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell LymphomaRecruiting · Phase 1 · Interventional · 21 enrolled · Mayo ClinicNCT06508463updated 2026-06-10
- A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or LymphomaRecruiting · Phase 1 · Interventional · 99 enrolled · Mayo ClinicNCT03017820updated 2026-06-10
- Study of PET Imaging With 18F-TFB in Patients With Thyroid CancerActive not recruiting · Interventional · 5 enrolled · Memorial Sloan Kettering Cancer CenterNCT03196518updated 2026-06-08
- VSV-IFNβ-NIS With Ipilimumab and Nivolumab for the Treatment of Advanced or Metastatic Clear Cell Renal Cell CarcinomaRecruiting · Phase 2 · Interventional · 18 enrolled · Mayo ClinicNCT07510334updated 2026-06-05
- Infection Prophylaxis in Total Joint ReplacementRecruiting · Phase 3 · Interventional · 21,006 enrolled · Hamilton Health Sciences CorporationNCT06126614updated 2026-05-22
- Parasitic Ulcer Treatment Trial PilotCompleted · Phase 2 · Interventional · 49 enrolled · University of California, San FranciscoNCT03484507updated 2026-05-07
- IoN- Is Ablative Radio-iodine Necessary for Low Risk Differentiated Thyroid Cancer PatientsActive not recruiting · Phase 2 · Phase 3 · Interventional · 504 enrolled · University College, LondonNCT01398085updated 2026-05-07
- Effectiveness of Platelet-rich Plasma Treatment of Knee OsteoarthritisActive not recruiting · Phase 2 · Interventional · 110 enrolled · Universidad Nacional de Entre RiosNCT05825105updated 2026-05-06
- Botulinum Toxin Type A for Frontal HyperhidrosisRecruiting · Interventional · 30 enrolled · Tishreen UniversityNCT07561580updated 2026-05-01
Frequently asked questions
- How does Sodium Iodide work?
- Mechanism-of-action classes: Physiochemical Activity; Unknown Cellular or Molecular Interaction.
- What is Sodium Iodide used for?
- According to FDA labeling, Sodium Iodide carries indications including: First aid to help prevent infection in minor cuts, scrapes, and burns.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Sodium Iodide?
- Sodium Iodide is classified as Physiochemical Activity, Unknown Cellular or Molecular Interaction, Decreased Respiratory Secretion Viscosity, Thyroid Gland Activity Alteration, Unknown Physiological Effect.
- What are the brand names for Sodium Iodide?
- Sodium Iodide is marketed under brand names including Iodopen.
Note. Data for
sodium-iodide is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.