Succinic Acid
/api/v1/drug/succinic-acidIndications
Sourced from openFDA- Directions: Turn tube upside down and rotate cap to release pellets into cap. Unscrew cap and without touching pellets tip them into the mouth under the tongue.
Dosage & administration
Sourced from openFDADIRECTIONS Take 15 minutes before meals Adults and children 12 years and older 5 pellets 3 times per day Children between 12 years and 6 years of age 3 pellets 3 times per day Children under 6 years 1 pellet 3 times per day to be dissolved into a little water
Warnings & precautions
Sourced from openFDAStop use and ask doctor if symptoms persist more than 5 days or worsen. If pregnant or breast-feeding ask a health professional before use. Keep out of reach of children.
FAERS reports
- 1Anaemia447.4%
- 2Pain437.2%
- 3Asthenia406.7%
- 4Renal Failure406.7%
- 5Anxiety386.4%
- 6Dyspnoea386.4%
- 7Cardiac Failure Congestive366.1%
- 8Diarrhoea355.9%
- 9Nausea355.9%
- 10Emotional Distress284.7%
- 11Dizziness264.4%
- 12Vomiting264.4%
- 13Injury223.7%
- 14Pneumonia223.7%
- 15Acute Kidney Injury213.5%
Literature
Recent PubMed references pinned to Succinic Acid as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Succinate drives breast cancer bone metastasis by activating the HIF1α/YTHDF1/YAP signaling axis to upregulate chemokine CXCL5 and disrupt the bone microenvironment.Apoptosis : an international journal on programmed cell death · 2026 · Xue J, Zhu C, Zhai Y, et al.PMID 42228026DOI 10.1007/s10495-026-02361-8
- Mechanisms Involved in Pathological Succinate-Mediated Signaling.International journal of molecular sciences · 2026 · Bernabe-Yepes B, Zazueta CPMID 42196310DOI 10.3390/ijms27104328
- Succinylation in cancer immunotherapy: mechanisms, biomarkers, and therapeutic implications.Frontiers in immunology · 2026 · Xie P, Long MH, Liu ZQ, et al.PMID 42183207DOI 10.3389/fimmu.2026.1794817
- Albiflorin contributes to Xuebijing-mediated protection against sepsis-associated acute kidney injury by modulating the succinate-PFKFB3 immunometabolic axis.International immunopharmacology · 2026 · Xu Y, Wei J, Chen M, et al.PMID 42134292DOI 10.1016/j.intimp.2026.116841
- Cocrystal mitigates the effects of elevated gastric pH on oral absorption of weakly basic drugs: a case study with ketoconazole-succinic acid cocrystal on beagle dogs.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2026 · Tucci YM, Machado TC, Sun D, et al.PMID 42107844DOI 10.1016/j.ejps.2026.107550
- Perspectives for Advancing Biotechnological Succinic Acid Production.Microbial biotechnology · 2026 · Gunkel C, Blombach BPMID 42050388DOI 10.1111/1751-7915.70363
- [Role of succinylation modification in central nervous system diseases].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025 · Gu M, Ren K, Zhang Z, et al.PMID 42033004DOI 10.11817/j.issn.1672-7347.2025.250226
- [Research progress on protein succination modification in cancer].Sheng li xue bao : [Acta physiologica Sinica] · 2026 · Ju QQ, Sun CPMID 42014332DOI 10.13294/j.aps.2026.0036
Clinical trials
The 10 most recently updated of 636 ClinicalTrials.gov registrations naming Succinic Acid as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)Recruiting · Phase 2 · Interventional · 461 enrolled · National Cancer Institute (NCI)NCT04546399updated 2026-06-12
- Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low TrialRecruiting · Phase 3 · Interventional · 1,978 enrolled · National Cancer Institute (NCI)NCT07391774updated 2026-06-12
- Siplizumab for Sickle Cell Disease TransplantTerminated · Phase 1 · Phase 2 · Interventional · 1 enrolled · Columbia UniversityNCT06078696updated 2026-06-10
- Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCMCompleted · Phase 3 · Interventional · 175 enrolled · CytokineticsNCT05767346updated 2026-06-09
- Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry)Recruiting · Phase 3 · Interventional · 236 enrolled · University of AarhusNCT06551246updated 2026-06-08
- Strategy for Withdrawal of Pharmacological Treatment for Urinary Incontinence in Children (StayDry)Active not recruiting · Phase 4 · Interventional · 216 enrolled · University of AarhusNCT06465576updated 2026-06-08
- A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night SweatsCompleted · Observational · 999 enrolled · Astellas Pharma Global Development, Inc.NCT06049797updated 2026-06-05
- Evaluation of Corticosteroid Administration Following Impacted Third Molar Surgery Using 3-Dimensional Facial AnalysisCompleted · Interventional · 60 enrolled · Irfan ÜstündağNCT07628166updated 2026-06-04
- Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic LymphomaActive not recruiting · Phase 3 · Interventional · 847 enrolled · National Cancer Institute (NCI)NCT02112916updated 2026-06-03
- Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory PneumonitisTerminated · Phase 2 · Interventional · 1 enrolled · ECOG-ACRIN Cancer Research GroupNCT04438382updated 2026-06-02
Frequently asked questions
- What is Succinic Acid used for?
- According to FDA labeling, Succinic Acid carries indications including: Directions: Turn tube upside down and rotate cap to release pellets into cap. Unscrew cap and without touching pellets tip them into the mouth under the tongue.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What are the brand names for Succinic Acid?
- Succinic Acid is marketed under brand names including Ferrex 150 Forte Plus, Multigen, Multigen Plus, Niferex-150.
succinic-acid is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.