Threonine

• Take 15 minutes before meals

DIRECTIONS Adults and children 12 years and older 20 drops in a little water, 2 times per day Children between 12 years and 6 years of age 10 drops in a little water, 2 times per day Children under 6 years 5 drops in a glass of water, 2 times per day

Stop use and ask doctor if symptoms persist more than 5 days. If pregnant or breast-feeding ask a health professional before use. Keep out of reach of children . In case of overdose, get medical help or contact a Poison Control Center right away. Contains ethyl alcohol 30%

• Jul 20, 1984NDANDA019018B Braun
• Aug 23, 1984NDANDA018931Baxter Hlthcare
• Sep 6, 1985NDANDA019398Otsuka Icu Medcl
• Oct 17, 1986NDANDA019492Otsuka Icu Medcl
• Dec 19, 1991NDANDA020041Otsuka Icu Medcl
• Dec 19, 1991NDANDA020015Otsuka Icu Medcl
• Mar 26, 1997NDANDA020678Baxter Hlthcare
• Sep 29, 1997NDANDA020734Baxter Hlthcare

1. 1Parenteral Nutrition Associated Liver Disease507.1%
2. 2Nausea446.2%
3. 3Pyrexia405.7%
4. 4Vomiting375.2%
5. 5Chills355.0%
6. 6Death355.0%
7. 7Dyspnoea304.2%
8. 8No Adverse Event304.2%
9. 9Diarrhoea263.7%
10. 10Asthenia243.4%
11. 11Palpitations233.3%
12. 12Pneumonia213.0%
13. 13Pruritus213.0%
14. 14Chest Discomfort202.8%
15. 15General Physical Health Deterioration182.5%

Recent PubMed references pinned to Threonine as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Formation kinetics of MeIQx in a threonine-glucose-creatinine system under oxidative conditions and its regulation in aquatic product thermal processing.
  Food research international (Ottawa, Ont.) · 2026 · Wang W, Lv M, Jiang G, et al.
  PMID 42116473DOI 10.1016/j.foodres.2026.119213
• Phosphorylated Tau at Threonine 181 Is Elevated in Amyotrophic Lateral Sclerosis Plasma.
  Muscle & nerve · 2026 · Petrozziello T, Mizerak E, Krishnamoorthy A, et al.
  PMID 42076823DOI 10.1002/mus.70266
• Multisegment C-to-N Sequential Ser/Thr Ligation Using Mmoc-Protected N-Terminal Serine/Threonine Peptide Salicylaldehyde Esters.
  Organic letters · 2026 · Tang J, Shu Q, Wang J, et al.
  PMID 42067509DOI 10.1021/acs.orglett.6c01528
• DeepOTG: An effective deep learning framework for identifying human protein O-linked threonine glycosylation sites via attention-based information bottleneck.
  International journal of biological macromolecules · 2026 · Ye Y, Xie P, Chung CR, et al.
  PMID 42025727DOI 10.1016/j.ijbiomac.2026.152152
• Near-UV and Visible Light Promote Iron-Catalyzed Site-Specific Radical Transformation of Threonine to Alanine in a Monoclonal Antibody Fc Domain (IgG1-Fc).
  Molecular pharmaceutics · 2026 · Espinoza Ballesteros M, Solis Rodriguez M, Tolbert TJ, et al.
  PMID 42011714DOI 10.1021/acs.molpharmaceut.5c01917
• Concentration-dependent threonine induces a functional shift from anammox to denitrification in an anammox reactor.
  Bioresource technology · 2026 · Miao Q, Xu J, Xie Y, et al.
  PMID 41997244DOI 10.1016/j.biortech.2026.134639
• Fast and Selective Labeling of Serine and Threonine in HFIP for Facile Editing of Peptide Alcohol Side Chains.
  Journal of the American Chemical Society · 2026 · Zhang D, Wang L, Miao X, et al.
  PMID 41979268DOI 10.1021/jacs.6c04665
• A composite protein enriched with threonine, lysine, and tryptophan improves osteoporosis by modulating the composition and metabolism of the gut microbiota.
  Food & function · 2026 · Fan C, Shi Z, Li B, et al.
  PMID 41915427DOI 10.1039/d5fo04652a

The 10 most recently updated of 109 ClinicalTrials.gov registrations naming Threonine as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Investigation of Medical Management to Prevent Episodes of Diverticulitis Trial
  Completed · Interventional · 71 enrolled · University of Washington
  NCT05681559updated 2026-06-12
• Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
  Recruiting · Phase 1 · Phase 2 · Interventional · 336 enrolled · IDEAYA Biosciences
  NCT03947385updated 2026-06-08
• Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid Cancer
  Active not recruiting · Phase 3 · Interventional · 153 enrolled · Novartis Pharmaceuticals
  NCT04940052updated 2026-06-04
• SMART Diets for MASLD
  Recruiting · Phase 2 · Interventional · 102 enrolled · Michigan State University
  NCT07459504updated 2026-06-01
• SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors
  Completed · Phase 2 · Interventional · 21 enrolled · Sarcoma Alliance for Research through Collaboration
  NCT03433183updated 2026-05-27
• Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies
  Recruiting · Phase 2 · Interventional · 700 enrolled · UNC Lineberger Comprehensive Cancer Center
  NCT07340541updated 2026-05-20
• A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment
  Recruiting · Phase 1 · Interventional · 20 enrolled · AstraZeneca
  NCT07343960updated 2026-05-20
• WOOP VA: Promoting Weight Management in Primary Care
  Completed · Interventional · 405 enrolled · VA Office of Research and Development
  NCT05014984updated 2026-05-20
• RMC-5552 Monotherapy in Adult Subjects With Recurrent Glioblastoma
  Terminated · Phase 1 · Interventional · 7 enrolled · Nicholas Butowski
  NCT05557292updated 2026-05-06
• Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome
  Completed · Phase 4 · Interventional · 10 enrolled · M.D. Anderson Cancer Center
  NCT04745910updated 2026-05-06

Frequently asked questions

What is Threonine used for?

According to FDA labeling, Threonine carries indications including: Take 15 minutes before meals. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What are the brand names for Threonine?

Threonine is marketed under brand names including Aminosyn 10%, Sulfite-Free, Aminosyn 3.5 % M, Sulfite Free, Aminosyn 8.5 % with Electrolytes, Sulfite-Free, Aminosyn 8.5%, Sulfite-Free, Aminosyn II 10 %, Aminosyn II 15%, Aminosyn II 8.5 % with Electrolytes, Sulfite-Free, Aminosyn II 8.5 %, Sulfite-Free.