Trichloroethylene
GET
/api/v1/drug/trichloroethyleneIndications
Sourced from openFDA- Uses: Uses: For temporary relief of minor: headache* rash* muscle aches* itching* dizziness* confusion* diarrhea* *Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.ICD-10: R51.9
Dosage & administration
Sourced from openFDADirections: Adults & children ages 12 years and over: Take 10 drops under the tongue 3 times a day, or as directed by your healthcare professional. Consult a physician for use in children under 12 years of age.
Warnings & precautions
Sourced from openFDAIf pregnant or breastfeeding , ask a health professional before use. Do not use if clear seal over the cap is broken or missing. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Stop use and ask a doctor if headache, rash, muscle aches, itching, dizziness, confusion, diarrhea, or other symptoms do not improve within 7 days or are accompanied by fever.
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
4 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Apnoea125%
- 2Cerebral Infarction125%
- 3Dizziness125%
- 4Drug Ineffective125%
- 5Influenza Like Illness125%
- 6Nausea125%
- 7Rash125%
- 8Stupor125%
Literature
Recent PubMed references pinned to Trichloroethylene as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- mTORC1-mediated inhibition of AMBRA1/PINK1/Parkin-dependent mitophagy contributes to renal podocyte injury in trichloroethylene-sensitized mice.Toxicology and applied pharmacology · 2026 · Bai Q, You C, Qin Z, et al.PMID 42225213DOI 10.1016/j.taap.2026.117894
- Micro-nano biochar interfaces promote adsorption-reduction coupling to accelerate bioelectrodechlorination in groundwater.Journal of hazardous materials · 2026 · Zhang Z, Lv M, Wang R, et al.PMID 42143457DOI 10.1016/j.jhazmat.2026.142393
- Characterization of multiple trichloroethene, cis-dichloroethene and 1,1-dichloroethene degrading propanotrophic communities.Journal of environmental management · 2026 · Faghihinezhad M, Eshghdoostkhatami Z, Cupples AM, et al.PMID 42143423DOI 10.1016/j.jenvman.2026.129957
- Regulating atomic hydrogen stabilization enables selective hydrodechlorination of trichloroethylene to ethylene.Water research · 2026 · Zhu S, Zhu S, Li L, et al.PMID 42127833DOI 10.1016/j.watres.2026.126059
- Dynamic sulfidation process of nanoscale zero-valent iron induced by sulfate-reducing bacteria and its effect on the reductive dechlorination of trichloroethylene.Environmental research · 2026 · Wan S, Zhang L, Zhuang S, et al.PMID 42035824DOI 10.1016/j.envres.2026.124563
- Modulating Surface Architecture of Sulfidated Nanoscale Zerovalent Iron for Synergistic Enhancement of Dechlorination Reactivity, Electron Selectivity, and Colloid Stability.Environmental science & technology · 2026 · Shen M, Liang Z, Guo Y, et al.PMID 41961994DOI 10.1021/acs.est.6c02054
- Enhancement of Mitochondria-Associated Membranes via GSK3β Activation: A Key Contributor to Trichloroethylene-Induced Renal Damage.Journal of biochemical and molecular toxicology · 2026 · Li Y, Zhu L, Bai Q, et al.PMID 41766457DOI 10.1002/jbt.70754
- Enhanced trichloroethylene degradation in groundwater: synergistic activation of persulfate by multivalent iron materials coupled with activated carbon.Water science and technology : a journal of the International Association on Water Pollution Research · 2026 · Zang X, Tu Y, Lyu S, et al.PMID 41764380DOI 10.2166/wst.2026.210
Clinical trials
The 7 most recently updated of 7 ClinicalTrials.gov registrations naming Trichloroethylene as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Addressing Tetrachloroethylene Exposure in an Impacted CommunityRecruiting · Interventional · 510 enrolled · Purdue UniversityNCT05819996updated 2025-03-18
- Diabetes Self-Management Plus Tai Chi EasyCompleted · Interventional · 28 enrolled · University of ArizonaNCT06180655updated 2024-12-06
- Cancer Markers Associated With Occupational Exposure to TrichloroethyleneCompleted · Observational · 125 enrolled · National Cancer Institute (NCI)NCT00481611updated 2020-11-03
- Pharmacotoxicology of Trichloroethylene MetabolitesCompleted · Interventional · 21 enrolled · University of FloridaNCT00874276updated 2015-06-04
- Pharmacotoxicology of Trichloroethylene MetabolitesTerminated · Interventional · 2 enrolled · University of FloridaNCT00865514updated 2015-06-03
- Pharmacotoxicology of Trichloroethylene MetabolitesCompleted · Phase 1 · Phase 2 · Interventional · 27 enrolled · University of FloridaNCT01128270updated 2014-05-07
- Trichloroethylene (TCE) Exposure in an Industrial PopulationCompleted · Observational · 27 enrolled · University of KentuckyNCT00839514updated 2012-06-07
Frequently asked questions
- What is Trichloroethylene used for?
- According to FDA labeling, Trichloroethylene carries indications including: Uses: Uses: For temporary relief of minor: headache* rash* muscle aches* itching* dizziness* confusion* diarrhea* *Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Trichloroethylene?
- Trichloroethylene is classified as Halogenated hydrocarbons.
Note. Data for
trichloroethylene is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.