Tryptophan

• USES: • For the temporary relief of symptoms including: • sleep issues • bloating • poor digestion • flatulence • occasional constipation These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.ICD-10: K59.00

DIRECTIONS: 1-10 drops under the tongue, 3 times a day or as directed by a health professional. Consult a physician for use in children under 12 years of age.

If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, contact a physician or Poison Control Center right away. Tamper Evident: Sealed for your protection. Do not use if seal is broken or missing.

• Jul 20, 1984NDANDA019018B Braun
• Aug 23, 1984NDANDA018931Baxter Hlthcare
• Sep 6, 1985NDANDA019398Otsuka Icu Medcl
• Oct 17, 1986NDANDA019492Otsuka Icu Medcl
• Dec 19, 1991NDANDA020041Otsuka Icu Medcl
• Dec 19, 1991NDANDA020015Otsuka Icu Medcl
• Mar 26, 1997NDANDA020678Baxter Hlthcare
• Sep 29, 1997NDANDA020734Baxter Hlthcare

1. 1Nausea1326.2%
2. 2Dyspnoea1266.0%
3. 3Fatigue1175.5%
4. 4Diarrhoea1135.3%
5. 5Dizziness1044.9%
6. 6Drug Ineffective974.6%
7. 7Pain904.3%
8. 8Headache894.2%
9. 9Vomiting854.0%
10. 10Pruritus844.0%
11. 11Rash783.7%
12. 12Asthenia743.5%
13. 13Insomnia683.2%
14. 14Off Label Use653.1%
15. 15Pyrexia622.9%

Recent PubMed references pinned to Tryptophan as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Mussel-inspired molecular strategy for ultrasensitive detection of multiple chiral molecules.
  Analytica chimica acta · 2026 · Liu Y, Li Y, Suo C, et al.
  PMID 42242812DOI 10.1016/j.aca.2026.345674
• A tryptophan metabolism-related gene signature predicts prognosis and immune features in cutaneous melanoma.
  Frontiers in immunology · 2026 · Zhao L, Li ZC, Tang ZY, et al.
  PMID 42238596DOI 10.3389/fimmu.2026.1806319
• Comparative unfolding of the Trp-cage miniprotein in anionic and cationic surfactants.
  PloS one · 2026 · Nnyigide OS, Byeon H, Okpete UE, et al.
  PMID 42234650DOI 10.1371/journal.pone.0347734
• A metabolic constraint in de novo NAD+ synthesis drives mucosal inflammation in IBD.
  Journal of Crohn's & colitis · 2026 · Wehkamp L, Harris DMM, Kim NM, et al.
  PMID 42223054DOI 10.1093/ecco-jcc/jjag043
• d-tryptophan potentiates dielectric barrier discharge cold plasma inactivation of Shewanella baltica through selective singlet oxygen generation.
  Food microbiology · 2026 · Chen J, Guo S, Li H, et al.
  PMID 42215213DOI 10.1016/j.fm.2026.105133
• Increasing plant protein sources in the diet modulates gut microbiota and tryptophan metabolism in men at cardiometabolic risk.
  Gut microbes · 2026 · Lépine G, Davila AM, Cueff G, et al.
  PMID 42199008DOI 10.1080/19490976.2026.2677951
• The Tryptophan Paradox: From Microbiome-Mediated Homeostasis to Tumor-Driven Immune Escape.
  International journal of molecular sciences · 2026 · Cho A, Wu C, Theodoropoulos G, et al.
  PMID 42196276DOI 10.3390/ijms27104296
• Humic acid and tryptophan prolong virus survival and infectivity: Molecular interactions and mechanisms.
  Water research · 2026 · Wang Z, Zhang CM, Wei YC, et al.
  PMID 42190392DOI 10.1016/j.watres.2026.126139

The 10 most recently updated of 182 ClinicalTrials.gov registrations naming Tryptophan as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Serotonin Variants & Gut Microbiota in Mental Health
  Not yet recruiting · Observational · 30 enrolled · Neurobiologix
  NCT07634458updated 2026-06-10
• Functionally Enhanced Limosilactobacillus Reuteri Probiotic Preparation in Elderly Patients With Functional Bowel Disorders
  Not yet recruiting · Interventional · 30 enrolled · Maanshan Shiqiye Hospital
  NCT07624656updated 2026-06-03
• Developing Precision Microbiota-Based Cocktail Modification Therapy to Delay the Progression of Parkinson's Disease (PD) - Use Preclinical Human Trials to Confirm the Impact of the Optimal "Probiotic Y7, Tryptophan and Branched-chain Amino Acid" Cocktail Formula on Early Stage PD Patients
  Recruiting · Interventional · 120 enrolled · Taipei Medical University
  NCT07619560updated 2026-06-02
• Study of IDO Inhibitor in Combination With Checkpoint Inhibitors for Adult Patients With Metastatic Melanoma
  Completed · Phase 1 · Phase 2 · Interventional · 131 enrolled · NewLink Genetics Corporation
  NCT02073123updated 2026-05-29
• OptiMAx Will Test Whether SQ-LNS Incentivises Vaccination Uptake in Rural Chad and Niger, With a Cost Effectiveness Analysis. It Will Also Look at Whether Having Received SQ-LNS Before Becoming Malnourished Leads to Better Outcomes for Children Treated Under the OptiMA Protocol.
  Recruiting · Interventional · 20,000 enrolled · Alliance for International Medical Action
  NCT07592260updated 2026-05-18
• Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
  Recruiting · Phase 3 · Interventional · 804 enrolled · ECOG-ACRIN Cancer Research Group
  NCT04423211updated 2026-05-15
• Impacts of Fermented Pea- and Legume-based Product on Gut Microbiota and Health
  Completed · Interventional · 56 enrolled · University of Eastern Finland
  NCT06743828updated 2026-05-12
• Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE Study
  Active not recruiting · Phase 3 · Interventional · 27 enrolled · ECOG-ACRIN Cancer Research Group
  NCT04484818updated 2026-05-05
• The Critical Link Between Gut Microbiome Dysfunction, Cravings and Relapse: RECLAIM-GUT TRIAL
  Active not recruiting · Interventional · 20 enrolled · University of Roehampton
  NCT07350538updated 2026-05-04
• Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial
  Active not recruiting · Phase 3 · Interventional · 2,050 enrolled · NRG Oncology
  NCT05050084updated 2026-05-04

Frequently asked questions

What is Tryptophan used for?

According to FDA labeling, Tryptophan carries indications including: USES: • For the temporary relief of symptoms including: • sleep issues • bloating • poor digestion • flatulence • occasional constipation These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Tryptophan?

Tryptophan is classified as Other antidepressants, Increased Serotonin Production.

What are the brand names for Tryptophan?

Tryptophan is marketed under brand names including Aminosyn 10%, Sulfite-Free, Aminosyn 3.5 % M, Sulfite Free, Aminosyn 8.5 % with Electrolytes, Sulfite-Free, Aminosyn 8.5%, Sulfite-Free, Aminosyn II 10 %, Aminosyn II 15%, Aminosyn II 8.5 % with Electrolytes, Sulfite-Free, Aminosyn II 8.5 %, Sulfite-Free.