Vitamin B6
GET
/api/v1/drug/vitamin-b6Mechanism of action
Sourced from openFDAMechanism-of-action class: Enzyme Interactions.
Dosage & administration
Sourced from openFDABefore, during and/or after pregnancy, one tablet daily, with a meal, or as directed by a licensed healthcare practitioner regardless of lactation status.
Warnings & precautions
Sourced from openFDAAccidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
5 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Dizziness240%
- 2Abdominal Pain120%
- 3Amniorrhoea120%
- 4Anhedonia120%
- 5Anxiety120%
- 6Arthralgia120%
- 7Asthenia120%
- 8Chondropathy120%
- 9Collagen Disorder120%
- 10Congenital Pseudarthrosis120%
- 11Diarrhoea120%
- 12Dysgeusia120%
- 13Dyspnoea120%
- 14Ear Congestion120%
- 15Emotional Distress120%
Literature
Recent PubMed references pinned to Vitamin B6 as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Associations between vitamin B6 and vitamin B12 intake and lung function: A cross-sectional study based on NHANES 2007 to 2012.Medicine · 2026 · Wang W, Gu YPMID 42260844DOI 10.1097/MD.0000000000049118
- Aging of the adaptive immune system affects the gut microbiome and systemic levels of vitamin B6.Microbiome · 2026 · Stahl S, Widmaier H, Sakk V, et al.PMID 42249511DOI 10.1186/s40168-026-02428-3
- Adolescent diagnosis of pyridoxine-dependent epilepsy.BMJ case reports · 2026 · Osman AA, Heva L, Kamal A, et al.PMID 42248600DOI 10.1136/bcr-2026-272010
- Glucose metabolism and transcriptional responses to vitamin B6 in tau-expressing fission yeast cells.Molecular biology reports · 2026 · Yilmazer M, Karaer Uzuner S, Palabiyik B, et al.PMID 42247019DOI 10.1007/s11033-026-12084-3
- Vitamin B6 Ameliorates Lipopolysaccharide-Induced Inflammation in Mouse Gastric Organoids.Cell biology international · 2026 · Xu A, Wu Y, Wang X, et al.PMID 42227274DOI 10.1002/cbin.70172
- Potential Role of Vitamin B6 as an Antioxidant via Pyridoxal-5'-Phosphate-Dependent Metabolic Pathways and Subsequent Activation of Nrf2 Signaling.Nutrients · 2026 · Kato N, Yang Y, Khedara A, et al.PMID 42196957DOI 10.3390/nu18101499
- Metabolic origins of hyperoxaluria: the critical role of precursors and vitamin B6 status in rats.Urolithiasis · 2026 · Ogawa YPMID 42191892DOI 10.1007/s00240-026-02009-x
- A Nonenzymatic Analogue of the Biosynthesis of Pyridoxal Vitamers.Journal of the American Chemical Society · 2026 · Nogal N, Basar AB, Minic Z, et al.PMID 42171396DOI 10.1021/jacs.6c01677
Clinical trials
The 10 most recently updated of 447 ClinicalTrials.gov registrations naming Vitamin B6 as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary TuberculosisRecruiting · Phase 3 · Interventional · 150 enrolled · National University Hospital, SingaporeNCT05473520updated 2026-06-09
- Composition for Treating Uterine Fibroid (SB-UF)Completed · Phase 4 · Interventional · 66 enrolled · Trieu, Nguyen Thi, M.D.NCT04762316updated 2026-06-08
- Immune-Mitochondrial Correction in Military RecruitsNot yet recruiting · Interventional · 200 enrolled · MIPO ClinicNCT07622147updated 2026-06-02
- Adjunctive Doxycycline for Central Nervous System TuberculosisRecruiting · Phase 2 · Interventional · 200 enrolled · National University Hospital, SingaporeNCT06446245updated 2026-06-01
- Study of Limited Versus Continuous Isoniazid Tuberculosis Preventive Therapy in HIV-infected Persons in BotswanaCompleted · Phase 4 · Interventional · 1,995 enrolled · Centers for Disease Control and PreventionNCT00164281updated 2026-05-27
- Vitamin B Complex for Inferior Alveolar Nerve Paresthesia RecoveryNot yet recruiting · Phase 4 · Interventional · 50 enrolled · University of Sao PauloNCT07592897updated 2026-05-20
- Impact of a Novel Functional Snack on Perimenopausal Symptoms and Well-beingRecruiting · Interventional · 20 enrolled · King's College LondonNCT07599930updated 2026-05-20
- The Danish Warfarin-Dialysis Study - Safety and Efficacy of Warfarin in Patients With Atrial Fibrillation on DialysisRecruiting · Phase 4 · Interventional · 718 enrolled · Nicholas CarlsonNCT03862859updated 2026-05-19
- Effect of a Food Intervention With a Prebiotic Alone or Combined With B-vitamins on Gut Microbiota Diversity, Inflammation and Mental Health Outcomes in Older Adults (GutFood)Recruiting · Interventional · 84 enrolled · University of UlsterNCT07592975updated 2026-05-18
- ATENEA Study: Adherence to Creatine-Based Nutritional Supplementation in Estrogen-Depleted WomenRecruiting · Observational · 100 enrolled · Margan BiotechNCT07580846updated 2026-05-12
Frequently asked questions
- How does Vitamin B6 work?
- Mechanism-of-action class: Enzyme Interactions.
- What class of drug is Vitamin B6?
- Vitamin B6 is classified as Enzyme Interactions, Cellular Activity Alteration.
- What are the brand names for Vitamin B6?
- Vitamin B6 is marketed under brand names including B-Natal, Folbee, Folbic, Folgard, Foltabs, MVC-Fluoride, Niva-Fol, Poly-Vi-Sol.
Note. Data for
vitamin-b6 is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.