Bone Loss
9 drugs54,225 FAERS reportsMedDRA PT
GET
/api/v1/reaction/bone-lossReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D001851
Diseases that affect the METABOLIC PROCESSES of BONE TISSUE.
Source: U.S. National Library of Medicine — MeSH (Bone Diseases, Metabolic)
Drugs reporting Bone Loss (9)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Elvitegravir3,63123%
- 2Cobicistat4,09520%
- 3Tenofovir Alafenamide7,25517%
- 4Tenofovir Disoproxil10,90916%
- 5Emtricitabine10,88814%
- 6Tenofovir11,33912%
- 7Rilpivirine1,9448.0%
- 8Darunavir7163.8%
- 9Bictegravir3,448—
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
Literature
Recent PubMed references pinned to Bone Diseases, Metabolic as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Romosozumab Achieves Consistent Lumbar Spine BMD Gains Across All BMI Categories: The Apparent Enhanced Response in Underweight Patients is a Mathematical Artifact of Percentage Change.Calcified tissue international · 2026 · Nakano R, Ichisawa A, Saruta K, et al.PMID 42203994DOI 10.1007/s00223-026-01553-3
- The Early Effect of Alendronate, Hop Extract and Their Combination on Bone Structural Properties in a Rat Model of Osteoporosis.Medical sciences (Basel, Switzerland) · 2026 · Rođak E, Grgac R, Kostanjšek R, et al.PMID 42201031DOI 10.3390/medsci14020239
- Context-Dependent Association Between Serum 25-Hydroxyvitamin D and Romosozumab Bone Mineral Density Response: A Stratified Analysis by Renal Function Category and Prior Treatment History in a Real-World Japanese Cohort.Nutrients · 2026 · Nakano R, Ichisawa A, Saruta K, et al.PMID 42197102DOI 10.3390/nu18101642
- Comparable Protective Effects of Low- and High-Dose MK-7 on Bone Structure and Remodeling in a Rat Model of Osteoporosis Induced by Estrogen Deficiency and Glucocorticoid Exposure.Nutrients · 2026 · Chiang HJ, Hsu SY, Leu S, et al.PMID 42197064DOI 10.3390/nu18101605
- Metabolic Phenotyping of Nutritional Rickets in Bangladeshi Children.Nutrients · 2026 · Wimborne EA, Ahmed S, Ward KA, et al.PMID 42197041DOI 10.3390/nu18101580
- Regulating Glucose Metabolism Enzymes for Osteoporosis Therapy: Current and Future Approaches.International journal of molecular sciences · 2026 · Zhang Z, Tian S, Li Q, et al.PMID 42196514DOI 10.3390/ijms27104536
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.