Osteonecrosis
16 drugs55,143 FAERS reportsMedDRA PT
GET
/api/v1/reaction/osteonecrosisReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D010020
Death of a bone or part of a bone, either atraumatic or posttraumatic.
Source: U.S. National Library of Medicine — MeSH (Osteonecrosis)
Drugs reporting Osteonecrosis (16)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Elvitegravir3,57422%
- 2Cobicistat4,04720%
- 3Tenofovir Alafenamide7,12417%
- 4Pamidronate53316%
- 5Tenofovir Disoproxil11,04316%
- 6Emtricitabine10,91114%
- 7Tenofovir11,44812%
- 8Rilpivirine1,8987.8%
- 9Darunavir8384.4%
- 10Nelfinavir673.2%
- 11Praziquantel93.1%
- 12Toremifene112.6%
- 13Thioguanine512.4%
- 14Tamoxifen1352.4%
- 15Imiglucerase841.8%
- 16Bictegravir3,370—
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
Literature
Recent PubMed references pinned to Osteonecrosis as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Evaluation of the effectiveness of total hip arthroplasty with preservation of the piriformis muscle using the posterolateral approach: A retrospective multicenter study.Medicine · 2026 · Zheng K, Ding H, Wang X, et al.PMID 42152432DOI 10.1097/MD.0000000000048771
- [Preservation of necrotic bone structures: an alternative to osteonecrosis of femoral head replacement therapy].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026 · Ma J, Sun W, Peng J, et al.PMID 42150896DOI 10.7507/1002-1892.202604061
- Tazarotene ameliorates steroid-induced osteonecrosis of the femoral head by activating autophagy.International immunopharmacology · 2026 · Wei Y, Tao K, Fan A, et al.PMID 42143934DOI 10.1016/j.intimp.2026.116820
- Efficacy of autologous stem cell at different doses combined with core decompression in the treatment of osteonecrosis of the femoral head: a systematic review and network meta-analysis.Frontiers in endocrinology · 2026 · Wei M, Yuan L, Feng G, et al.PMID 42100192DOI 10.3389/fendo.2026.1720437
- Involucrum Formation Leading to Healing in Stage 3 Medication-Related Osteonecrosis of the Jaws.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry · 2026 · Masri D, Bar-Hai D, Ghanaiem O, et al.PMID 42093325DOI 10.1111/scd.70184
- Efficacy and safety of robot-assisted core decompression for osteonecrosis of the femoral head: a meta-analysis of single-arm studies.BMC musculoskeletal disorders · 2026 · Liu H, Jiang D, Wang F, et al.PMID 42092884DOI 10.1186/s12891-026-09777-y
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.