Coma
24 drugs5,868 FAERS reportsMedDRA PT
GET
/api/v1/reaction/comaReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D003128
A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Drugs reporting Coma (24)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Escherichia Coli20754%
- 2Propylhexedrine712%
- 3Nalmefene410%
- 4Fexinidazole110%
- 5Flumazenil708.4%
- 6Flurazepam266.8%
- 7Loxapine2296.2%
- 8Pentoxifylline2505.9%
- 9Trimipramine855.9%
- 10Sodium Nitrite35.6%
- 11Trihexyphenidyl505.3%
- 12Oxazepam1,0645.1%
- 13Fomepizole84.3%
- 14Ivermectin2464.0%
- 15Acamprosate123.8%
- 16Clomipramine1703.8%
- 17Ibutilide13.4%
- 18Clorazepate613.2%
- 19Dipotassium613.2%
- 20Pimozide143.0%
- 21Diazepam3,1642.6%
- 22Zanidatamab12.3%
- 23Eptifibatide152.0%
- 24Ethanol1191.5%
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
- Intentional Overdose9 shared · 0.21
- Drug Abuse12 shared · 0.18
- Suicide Attempt10 shared · 0.17
- Depressed Level Of Consciousness5 shared · 0.14
- Alcohol Poisoning3 shared · 0.13
- Pneumonia Aspiration3 shared · 0.10
- Brain Oedema3 shared · 0.10
- Cardio-respiratory Arrest5 shared · 0.09
- Overdose11 shared · 0.09
- Toxicity To Various Agents15 shared · 0.09
Literature
Recent PubMed references pinned to Coma as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Prevalence and outcomes of cerebral vasculitis in patients with comatose ventilated meningitis in the dexamethasone era.BMC research notes · 2026 · Roesch N, Canet EPMID 42135797DOI 10.1186/s13104-026-07871-x
- Multi-center pressure reactivity index temporal trajectories for predicting outcome in comatose subarachnoid hemorrhage patients.Neurosurgical review · 2026 · Chang JJ, Foreman B, Kepplinger D, et al.PMID 42120701DOI 10.1007/s10143-026-04323-9
- Spectral mapping reveals a resemblance of the anesthetic brain state to both sleep and coma.Proceedings of the National Academy of Sciences of the United States of America · 2026 · Helfrich JD, Szaflarski J, Nævra MCJ, et al.PMID 42114012DOI 10.1073/pnas.2514098123
- Anesthetic Management of Brain-Dead Donors During Organ Retrieval: Hemodynamic Effects and Potential Organ-Protective Implications - A Retrospective Analysis of 85 Cases.Transplant international : official journal of the European Society for Organ Transplantation · 2026 · Englbrecht JS, Piegeler T, Küllmar M, et al.PMID 42094637DOI 10.3389/ti.2026.16262
- Inhibitory Effect of Music Therapy Combined with Comfort Care on Reflux Events during Enteral Nutrition in Comatose Patients.Noise & health · 2026 · Sheng S, Zhang A, Wang J, et al.PMID 42085093DOI 10.4103/nah.nah_146_25
- Novel Examination of the Impact of Time and Reliability on Minimal Detectable Differences Using the Coma Recovery Scale-Revised.Archives of physical medicine and rehabilitation · 2026 · Grady-Dominguez P, Kozlowski AJ, Cogan AM, et al.PMID 42083820DOI 10.1016/j.apmr.2025.09.037
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.