Parkinson^s Disease
16 drugs11,761 FAERS reportsMedDRA PT
GET
/api/v1/reaction/parkinson-s-diseaseReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D010300
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Source: U.S. National Library of Medicine — MeSH (Parkinson Disease)
Drugs reporting Parkinson^s Disease (16)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Triethanolamine150%
- 2Amber114%
- 3Safinamide947.5%
- 4Tyramine27.4%
- 5Entacapone3177.0%
- 6Levodopa3,3895.8%
- 7Opicapone1195.6%
- 8Rotigotine7645.4%
- 9Carbidopa2,7815.4%
- 10Rasagiline5224.8%
- 11Pimavanserin2,1844.2%
- 12Amantadine7253.7%
- 13Tolcapone113.2%
- 14Rivastigmine5823.1%
- 15Istradefylline1783.0%
- 16Selegiline912.6%
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
- On And Off Phenomenon6 shared · 0.33
- Hallucination, Visual5 shared · 0.31
- Dyskinesia11 shared · 0.28
- Freezing Phenomenon4 shared · 0.24
- Hallucination14 shared · 0.23
- Balance Disorder7 shared · 0.14
- Device Issue5 shared · 0.13
- Bradykinesia2 shared · 0.12
- Muscle Rigidity2 shared · 0.12
- Mobility Decreased4 shared · 0.11
Literature
Recent PubMed references pinned to Parkinson Disease as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Blm10/PA200-Activated 20S Proteasomes Promote α-Synuclein Degradation and Bypass Proteasome Inhibition in Parkinson's Disease Models.Aging cell · 2026 · Ali TT, Zhornyak A, Merghani M, et al.PMID 42206954DOI 10.1111/acel.70566
- Long-Term Surgical Outcomes and Influential Factors of Subthalamic Nucleus Deep Brain Stimulation for Dyskinesia in Parkinson's Disease: A 3-Year Longitudinal Cohort Study.Clinical interventions in aging · 2026 · Wang S, Xue T, Ma R, et al.PMID 42205153DOI 10.2147/CIA.S600031
- Genetic Variants and Clinical Characteristics of Young-Onset Parkinson's Disease in the Hakka Population of Western Fujian.Brain and behavior · 2026 · Pan LY, Guo F, Zheng C, et al.PMID 42204920DOI 10.1002/brb3.71504
- Urinary Biomarkers in Parkinson's Disease: A Structured Integrative Review of Pathophysiological Pathways.Medical sciences (Basel, Switzerland) · 2026 · Santos HQP, Sumita NM, Alberto-Silva C, et al.PMID 42201050DOI 10.3390/medsci14020258
- Sex Differences in the Treatment of People with Parkinson's Disease with a Device-Aided Therapy: A Prospective Real-World Study.Medical sciences (Basel, Switzerland) · 2026 · Santos García D, Solleiro Vidal Á, Blázquez Estrada M, et al.PMID 42201009DOI 10.3390/medsci14020217
- [Chronic diarrhea in Parkinson's disease during Levodopa therapy].Praxis · 2026 · Macht A, Cathomas G, Bauer E, et al.PMID 42200385DOI 10.23785/PRAXIS.2026.05.006
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.