Stevens-johnson Syndrome

13 drugs1,755 FAERS reportsMedDRA PT

GET

/api/v1/reaction/stevens-johnson-syndrome

Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.

DefinitionNLM MeSH D013262

Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.

Source: U.S. National Library of Medicine — MeSH (Stevens-Johnson Syndrome)

Drugs reporting Stevens-johnson Syndrome (13)

Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.

1Ethacrynate117%
2Hetastarch148.6%
3Ceftobiprole24.7%
4Vaborbactam24.1%
5Lincomycin103.5%
6Griseofulvin93.2%
7Glycine323.1%
8Phenytoin1,2253.1%
9Enfortumab1822.8%
10Fosphenytoin622.5%
11Nevirapine1902.1%
12Ceftaroline131.7%
13Ceftaroline Fosamil131.7%

Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.

Literature

Recent PubMed references pinned to Stevens-Johnson Syndrome as a MeSH major topic. About the reaction term itself — not about any specific drug.

Integrating Pharmacogenomics and Network Topology for Machine Learning Prediction of HLA-Associated Severe Cutaneous Adverse Drug Reactions.
International journal of molecular sciences · 2026 · Ponduan T, Kunsombut A, Paklao T, et al.
PMID 42196169DOI 10.3390/ijms27104187
The Effects of Nursing Care Applied in the Intensive Care Unit on a Case of Toxic Epidermal Necrolysis: A Case Report.
Nursing in critical care · 2026 · Gulsoy Z, Özdemir Kol İ
PMID 42132071DOI 10.1111/nicc.70513
Pharmacovigilance of paracetamol-induced Stevens-Johnson Syndrome and toxic epidermal necrolysis in the Indian population.
Indian journal of pharmacology · 2026 · Ray RS, Yadav A, Bhushan S, et al.
PMID 42060809DOI 10.4103/ijp.ijp_495_23
A Rare Case of Stevens-Johnson Syndrome in a Young Patient Presenting With Odynophagia Following Antibiotic Use.
The American journal of case reports · 2026 · Tomasini J, Sajdlowska J, Crisafulli G, et al.
PMID 42054279DOI 10.12659/AJCR.951823
Antimicrobial toxic epidermal necrolysis in an ICU patient with multisystem organ failure and sepsis.
BMJ case reports · 2026 · Phu K, Li C, Pauplis C, et al.
PMID 42009454DOI 10.1136/bcr-2025-269803
Pilot Study to Improve In Vitro Identification of Culprit Drugs in SJS/TEN Using Granzyme B and Granulysin Secretion Assays.
Journal of immunology research · 2026 · Srinoulprasert Y, Ud-Naen S, Tansit T, et al.
PMID 41964304DOI 10.1155/jimr/8497493

What this is

Stevens-johnson Syndrome is a MedDRA Preferred Term reported on FAERS adverse-event submissions. Each entry below is one drug from the dataset whose FAERS reports mention this reaction.

MeSH descriptor

ID: D013262
Name: Stevens-Johnson Syndrome
Synonyms: Stevens Johnson Syndrome, Epidermal Necrolysis, Toxic, Epidermal Necrolyses, Toxic, Necrolyses, Toxic Epidermal, Necrolysis, Toxic Epidermal, Toxic Epidermal Necrolyses, Toxic Epidermal Necrolysis, Lyell's Syndrome, Lyell's Syndromes, Lyell Syndrome, Syndrome, Lyell's, Syndromes, Lyell's, Nonstaphylococcal Scalded Skin Syndrome, Scalded Skin Syndrome, Nonstaphylococcal, Drug-Induced Stevens Johnson Syndrome, Drug Induced Stevens Johnson Syndrome, Drug-Induced Stevens-Johnson Syndrome, Drug-Induced Stevens-Johnson Syndromes, Stevens-Johnson Syndrome, Drug-Induced, Stevens-Johnson Syndromes, Drug-Induced, Mycoplasma-Induced Stevens-Johnson Syndrome, Mycoplasma Induced Stevens Johnson Syndrome, Stevens-Johnson Syndrome, Mycoplasma-Induced, Syndrome, Mycoplasma-Induced Stevens-Johnson, Mycoplasma-Induced Stevens Johnson Syndrome, Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum, Stevens Johnson Syndrome Toxic Epidermal Necrolysis, Stevens Johnson Syndrome Toxic Epidermal Necrolysis Spectrum, Stevens-Johnson Syndrome Toxic Epidermal Necrolysis, Toxic Epidermal Necrolysis Stevens Johnson Syndrome, Toxic Epidermal Necrolysis Stevens Johnson Syndrome Spectrum, Toxic Epidermal Necrolysis Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis Stevens-Johnson Syndrome Spectrum
Tree: C07.465.864.500, C17.800.174.600.900, C17.800.229.400.683, C17.800.865.475.683, C20.543.418.787, C25.100.468.380.900

Sits under

Full MeSH record

Try the API

cURLbash

curl https://pharmacopeia.dev/api/v1/reaction/stevens-johnson-syndrome

Source

Source: openFDA · FAERS
Coding: MedDRA Preferred Term
Aliases: —

open.fda.gov/data/faers/

Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.

Stevens-johnson Syndrome

DefinitionNLM MeSH D013262

Drugs reporting Stevens-johnson Syndrome (13)

Related reactions

Literature

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