Diethyltoluamide
GET
/api/v1/drug/diethyltoluamideIndications
Sourced from openFDA- You can spray it on your skin or clothes.
Dosage & administration
Sourced from openFDAfor external use only
Warnings & precautions
Sourced from openFDAdo not use for the following people: infants under six months do not use excessive amounts or for long periods of time beyond the required do not use it in an enclosed area
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
11 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Toxicity To Various Agents655%
- 2Encephalopathy545%
- 3Hepatic Failure436%
- 4Sunburn436%
- 5Accidental Exposure To Product327%
- 6Product Use In Unapproved Indication327%
- 7Skin Discolouration327%
- 8Acute Kidney Injury218%
- 9Drug Interaction218%
- 10Mental Status Changes218%
- 11Multiple Organ Dysfunction Syndrome218%
- 12Pneumonia218%
- 13Renal Failure218%
- 14Sepsis218%
- 15Agitation19.1%
Literature
Recent PubMed references pinned to Diethyltoluamide as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Associative learning switches DEET valence from aversive to appetitive in Aedes aegypti.The Journal of experimental biology · 2026 · Lazzari CR, De Luca D, Nally A, et al.PMID 42210902DOI 10.1242/jeb.251935
- Synergistic effects of two commonly used personal care products, benzophenone-3 (BP-3) and N,N-diethyl-meta-toluamide (DEET), on amphibian survival and development.Environmental toxicology and pharmacology · 2026 · Peluso J, de la Torre M, Teglia CM, et al.PMID 42009148DOI 10.1016/j.etap.2026.105027
- N,N-diethyl-meta-toluamide (DEET) exposure produces rapid and permanent damage in turfgrass.Ecotoxicology and environmental safety · 2026 · Qiao S, Endres A, Rohlfsen M, et al.PMID 41996793DOI 10.1016/j.ecoenv.2026.120137
- Evaluation of the efficacy of 20% IR3535(®) with a sustained-release formulation and 25% DEET insect repellents against mosquitoes in a field setting in Ghana.Parasites & vectors · 2025 · Abudu M, Asafu-Adjaye A, Osei JHN, et al.PMID 41057954DOI 10.1186/s13071-025-06946-1
- Designing a simple bioassay to assess repellents against Aedes aegypti (Diptera: Culicidae): investigating stimuli sources and exposure duration on mosquito behavior.Brazilian journal of biology = Revista brasleira de biologia · 2025 · Santos AN, Silva AAEPMID 41036953DOI 10.1590/1519-6984.293116
- In Vivo Effects of N,N-Diethyl-Meta-Toluamide (DEET) Exposure on Sinonasal Epithelia in a Murine Model.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026 · Lee JT, Cheng MY, Srivatsan ES, et al.PMID 40879168DOI 10.1002/ohn.70000
- Toxicity assessment of N, N-Diethyl-meta-toluamide (DEET) in zebrafish embryos.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2025 · Zhang H, Liu C, Sun Y, et al.PMID 40683430DOI 10.1016/j.cbpc.2025.110293
- A physiologically based kinetic model for quantifying human exposure to DEET.International journal of hygiene and environmental health · 2025 · Kim MS, Hamadeh A, Kowalski J, et al.PMID 40582233DOI 10.1016/j.ijheh.2025.114616
Clinical trials
The 4 most recently updated of 4 ClinicalTrials.gov registrations naming Diethyltoluamide as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- eSET or eDET Associated to PGT in IVFCompleted · Interventional · 200 enrolled · University of Sao Paulo General HospitalNCT03758833updated 2024-07-03
- Reducing Malaria Transmission in Forest-going Mobile and Migrant Populations in MyanmarUnknown · Interventional · 1,200 enrolled · Macfarlane Burnet Institute for Medical Research and Public Health LtdNCT05025761updated 2021-11-04
- Field Efficacy Of Insecticide Treated Uniforms And Skin Repellents for Malaria PreventionUnknown · Phase 3 · Interventional · 1,500 enrolled · Ifakara Health InstituteNCT02938975updated 2017-06-06
- Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDRUnknown · Phase 3 · Interventional · 5,000 enrolled · London School of Hygiene and Tropical MedicineNCT00938379updated 2009-07-14
Frequently asked questions
- What is Diethyltoluamide used for?
- According to FDA labeling, Diethyltoluamide carries indications including: You can spray it on your skin or clothes.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Diethyltoluamide?
- Diethyltoluamide is classified as Other insecticides and repellents.
Note. Data for
diethyltoluamide is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.