Hepatic Failure
12 drugs797 FAERS reportsMedDRA PT
GET
/api/v1/reaction/hepatic-failureReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D017093
Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
Source: U.S. National Library of Medicine — MeSH (Liver Failure)
Drugs reporting Hepatic Failure (12)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Arsenic Trisulfide1100%
- 2Diethyltoluamide436%
- 3Epidermal Growth Factor120%
- 4Doxapram314%
- 5Brincidofovir75.1%
- 6Nitisinone454.8%
- 7Terlipressin124.2%
- 8Caffeic Acid24.1%
- 9Floxuridine53.5%
- 10Lusutrombopag12.6%
- 11Rifaximin4872.4%
- 12Entecavir2292.0%
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
- Hepatic Encephalopathy3 shared · 0.20
- Liver Disorder3 shared · 0.12
- Hepatic Cirrhosis2 shared · 0.12
- Ammonia Increased2 shared · 0.11
- Encephalopathy3 shared · 0.09
- Hepatocellular Carcinoma2 shared · 0.09
- Bone Marrow Failure2 shared · 0.07
- Candida Infection2 shared · 0.07
- Drug-induced Liver Injury2 shared · 0.07
- Blood Bilirubin Increased2 shared · 0.06
Literature
Recent PubMed references pinned to Liver Failure as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Zinc deficiency and sarcopenia define a metabolic frailty phenotype predicting hepatic encephalopathy and early mortality in cirrhosis.Metabolic brain disease · 2026 · Méndez-Guerrero O, Carranza-Carrasco A, Guerrero-Guerrero R, et al.PMID 42207388DOI 10.1007/s11011-026-01879-9
- Combined Liver-Small Bowel Transplant in Children.Gastroenterology clinics of North America · 2026 · Alaniz MJ, Withington C, Tzvetanov IG, et al.PMID 42203394DOI 10.1016/j.gtc.2026.01.003
- Clinical Challenges in the Management of Hepatic Encephalopathy in Older Patients with Cirrhosis: A Nationwide Italian Physician-Reported Survey.Medicina (Kaunas, Lithuania) · 2026 · Lapenna L, Di Cola S, Nardelli S, et al.PMID 42195208DOI 10.3390/medicina62050955
- Role of Gram-Negative Bacterial Infections in Acute-On-Chronic Liver Failure.Liver international : official journal of the International Association for the Study of the Liver · 2026 · Cadoli C, Müller V, Welsch C, et al.PMID 42188459DOI 10.1111/liv.70710
- Multi-Omics Identified Factor V Leiden as a Novel Predictor of 90-Day Mortality in Artificial Liver-Supported ACLF: A Translational Study.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026 · Zhao W, Ruan H, Li L, et al.PMID 42186733DOI 10.1096/fj.202504139RRR
- Midodrine versus placebo in patients with acute-on-chronic liver failure with ascites-A randomized trial (MIDAS trial).Hepatology communications · 2026 · Kulkarni AV, Venishetty S, Prasanna S, et al.PMID 42172504DOI 10.1097/HC9.0000000000000966
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.