Nickel
Standardized Chemical AllergenCell-mediated ImmunityIncreased Histamine ReleaseUS-FDASourced from openFDA
GET
/api/v1/drug/nickelIndications
Sourced from openFDA- Relieves headache from mental overexertion * Uses: See symptoms on front panel.ICD-10: R51.9
Dosage & administration
Sourced from openFDAAdults and children: At the onset of symptoms, dissolve 5 pellets under the tongue 3 times a day until symptoms are relieved or as directed by a doctor
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
610 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Drug Hypersensitivity8514%
- 2Diarrhoea376.1%
- 3Pain355.7%
- 4Fatigue335.4%
- 5Headache335.4%
- 6Arthralgia315.1%
- 7Dizziness284.6%
- 8Nausea284.6%
- 9Dyspnoea254.1%
- 10Rash243.9%
- 11Pain In Extremity233.8%
- 12Pruritus203.3%
- 13Gait Disturbance193.1%
- 14Asthenia183.0%
- 15Insomnia183.0%
Literature
Recent PubMed references pinned to Nickel as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Nitinol shape memory alloy (NiTi SMA): Materials and applications in medical devices.Journal of applied biomaterials & functional materials · 2026 · Gholizadeh S, Sivarasu SPMID 42260713DOI 10.1177/22808000261453192
- Interface-engineered nickel oxyhydroxide on carbon nanofibers for efficient urea oxidation and wastewater-to-energy conversion.PloS one · 2026 · Barakat NAM, Saadawi A, Erfan OM, et al.PMID 42241426DOI 10.1371/journal.pone.0347020
- A novel nail polish/graphite/nickel nanoparticles-based disposable screen-printed sensor for enhanced voltammetric detection of mefenamic acid in environmental water samples.Mikrochimica acta · 2026 · Teixeira LEDC, Silva FWL, Macedo AA, et al.PMID 42240721DOI 10.1007/s00604-026-08105-4
- Real-time in-situ H(2)O(2) quantification in high-biomass marine environments with a robust NiCo-MOF nanosheet electrode.Analytica chimica acta · 2026 · Zhao D, Lu Y, Mao H, et al.PMID 42219639DOI 10.1016/j.aca.2026.345658
- Nickel-Catalyzed Construction of Dibenzoxathiepine and Dibenzothiazepine Frameworks as H-Telo G-Quadruplex DNA Binders.ChemMedChem · 2026 · Ahamed SS, Bag S, Chinnadurai RK, et al.PMID 42219164DOI 10.1002/cmdc.70329
- Nickel binding shifts Helicobacter pylori HypA toward compact conformations.Journal of inorganic biochemistry · 2026 · Ciurli S, Mazzei L, Zambelli B, et al.PMID 42217269DOI 10.1016/j.jinorgbio.2026.113350
- Beyond S-cross section design: mechanical properties, metallurgical features and shaping ability of two nickel-titanium rotary instruments in double curved canals.Clinical oral investigations · 2026 · Tres L, Só GB, de Oliveira Neto RS, et al.PMID 42213194DOI 10.1007/s00784-026-06953-1
- Walking the Tight Rope for a Diagnosis: A Case Report of a Dermatological Enigma of Surgical Device Nickel Allergy.Orthopedic nursing · 2026 · Quinn M, Faulkner M, Staino M, et al.PMID 42212840DOI 10.1097/NOR.0000000000001209
Clinical trials
The 10 most recently updated of 140 ClinicalTrials.gov registrations naming Nickel as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- EFFECT OF NITI SYSTEMS AND XP-ENDO FINISHER ON POSTOPERATIVE PAINRecruiting · Interventional · 80 enrolled · BUSRA OZTURKNCT07642596updated 2026-06-11
- Leaf Expander Versus Hyrax Expander in Mixed Dentition Patients With Posterior Crossbite.Recruiting · Interventional · 30 enrolled · Cairo UniversityNCT07301918updated 2026-06-04
- Treatment Outcome of Elastomeric and Nickel-Titanium Separators in Tooth SeparationNot yet recruiting · Interventional · 30 enrolled · 3D-AlignersNCT07591454updated 2026-05-15
- Comparison of Patient-reported Pain After Initial Archwire PlacementRecruiting · Interventional · 126 enrolled · University of Colorado, DenverNCT03906422updated 2026-05-14
- Evaluation of Zygomatic Implant Placement Accuracy Using Fully Metallic vs Resin-based Static Surgical Guides in Severely Atrophic MaxillaRecruiting · Interventional · 4 enrolled · Future University in EgyptNCT07551024updated 2026-05-07
- Nickel SensitivityTerminated · Interventional · 9 enrolled · Rush University Medical CenterNCT04058743updated 2026-05-01
- Effects of Laser Therapy and Vitamin D Pills on Braces Tooth Movement: A Random Controlled StudyActive not recruiting · Interventional · 50 enrolled · Universiti Sains MalaysiaNCT07286474updated 2026-04-28
- A Clinical Study of GeminiOne TEER System for the Treatment of Severe, Symptomatic MR.Recruiting · Interventional · 15 enrolled · Sierra Valve LLCNCT07086534updated 2026-04-24
- Clinical Performance of the I-arch System During the Initial Stage of Orthodontic TreatmentRecruiting · Interventional · 34 enrolled · Tabark H. OmranNCT07264127updated 2026-04-22
- Effect of Instrumentation Systems and Sealers on Postoperative PainNot yet recruiting · Interventional · 144 enrolled · European University of LefkeNCT07526844updated 2026-04-21
Frequently asked questions
- What is Nickel used for?
- According to FDA labeling, Nickel carries indications including: Relieves headache from mental overexertion * Uses: See symptoms on front panel.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Nickel?
- Nickel is classified as Standardized Chemical Allergen, Cell-mediated Immunity, Increased Histamine Release.
Note. Data for
nickel is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.