Nitrogen
Medical gasesUnknown Cellular or Molecular InteractionUnknown Physiological EffectUS-FDASourced from openFDA
GET
/api/v1/drug/nitrogenMechanism of action
Sourced from openFDAMechanism-of-action class: Unknown Cellular or Molecular Interaction.
Approval history
Sourced from openFDA- Jun 16, 2013NDANDA205713Air Liquid Industrial Us Lp
- Jun 23, 2013NDANDA205738Air Liquide Large Industries Us Lp
- Jul 5, 2013NDANDA205816Linde Gas Puerto Rico Inc
- Jul 5, 2013NDANDA205764Linde North America Inc
- Jul 5, 2013NDANDA205766Linde North America Inc
- Jul 13, 2013NDANDA205829Air Liquide America Lp
- Jul 14, 2013NDANDA205805Norco Inc
- Jul 16, 2013NDANDA205839Airgas Merchants Gases Llc
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
104 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Malaise109.6%
- 2Off Label Use98.7%
- 3Drug Interaction76.7%
- 4Accidental Exposure To Product65.8%
- 5Completed Suicide54.8%
- 6Dyspnoea54.8%
- 7Nausea54.8%
- 8Product Leakage54.8%
- 9Psoriasis54.8%
- 10Weight Decreased54.8%
- 11Death43.8%
- 12Dry Gangrene43.8%
- 13Extremity Necrosis43.8%
- 14Haemodynamic Instability43.8%
- 15Injection Site Reaction43.8%
Literature
Recent PubMed references pinned to Nitrogen as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Enhanced deep nitrogen removal from low C/N wastewater via manganese-catalyzed iron-carbon micro-electrolysis coupled biological system: performance, mechanism, and microbial adaptability.World journal of microbiology & biotechnology · 2026 · Liu H, Wang K, Sha F, et al.PMID 42252354DOI 10.1007/s11274-026-05075-w
- Soil Organic Carbon and pH Interactions Mediate N Impacts on Nematode Abundance and Composition.Global change biology · 2026 · Wu S, He T, Hu Z, et al.PMID 42249750DOI 10.1111/gcb.70963
- Elevated Nitrogen and Phosphorus Levels Suggest High Metabolic Demands in Himalayan High-Elevation Plants.Physiologia plantarum · 2026 · Chlumská Z, Macek M, Altman J, et al.PMID 42246767DOI 10.1111/ppl.70955
- Multicolor N, P Co-Doped Carbon Quantum Dots for Sensing, Fingerprint Imaging, and Fruit Preservation.Luminescence : the journal of biological and chemical luminescence · 2026 · Li K, Guan M, Wang G, et al.PMID 42240950DOI 10.1002/bio.70530
- Long-Term Inorganic Nitrogen Fertilization Drives a Trade-Off in the Soybean Symbiotic Network From Low-Loss Fixation to High-Loss Metabolism.Molecular ecology · 2026 · Zhang H, Sun H, Li H, et al.PMID 42233733DOI 10.1111/mec.70421
- Intake, Digestibility, Nitrogen Balance, Rumen, and Blood Parameters of Cattle Supplemented With Acacia mearnsii Extract.Animal science journal = Nihon chikusan Gakkaiho · 2026 · Dos Santos FM, Bezerra LR, Vieira JF, et al.PMID 42229918DOI 10.1111/asj.70195
- Multidimensional regulation of biological nitrogen removal by quorum sensing signals: from molecular mechanisms to system enhancement.Bioresource technology · 2026 · Wei Z, Han Y, Wang H, et al.PMID 42229599DOI 10.1016/j.biortech.2026.135063
- Heterotrophic nitrification and aerobic denitrification by Pseudomonas sp. HE-16: performance and mechanism for nitrogen and phosphorus removal.Biodegradation · 2026 · Zhang Y, Che F, Xu J, et al.PMID 42228212DOI 10.1007/s10532-026-10318-6
Clinical trials
The 10 most recently updated of 8,775 ClinicalTrials.gov registrations naming Nitrogen as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the LungRecruiting · Phase 2 · Phase 3 · Interventional · 189 enrolled · National Cancer Institute (NCI)NCT05058651updated 2026-06-12
- Eflornithine (DFMO) for Ewing Sarcoma and OsteosarcomaRecruiting · Phase 2 · Interventional · 406 enrolled · Milton S. Hershey Medical CenterNCT07321912updated 2026-06-12
- Phase I/II Study of Engineered T Cell Receptor-Modified NK Cells Targeting PRAME in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Myeloid MalignanciesRecruiting · Phase 1 · Phase 2 · Interventional · 44 enrolled · M.D. Anderson Cancer CenterNCT06383572updated 2026-06-12
- Efficacy and Safety of the CloB2M (Clofarabine Combined With Busulfan and Melphalan) Conditioning Regimen in Allogeneic Hematopoietic Stem Cell Transplantation for Adult Patients With Acute Myeloid Leukemia in First Complete RemissionNot yet recruiting · Interventional · 30 enrolled · Institute of Hematology & Blood Diseases Hospital, ChinaNCT07644481updated 2026-06-12
- Hot Flashes and Neurovascular Function in WomenRecruiting · Interventional · 120 enrolled · Mayo ClinicNCT05193968updated 2026-06-12
- A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed OsteosarcomaRecruiting · Phase 2 · Phase 3 · Interventional · 1,122 enrolled · National Cancer Institute (NCI)NCT05691478updated 2026-06-12
- CD30 CAR for CD30+ NSGCTCompleted · Phase 2 · Interventional · 2 enrolled · UNC Lineberger Comprehensive Cancer CenterNCT05634785updated 2026-06-12
- A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)Recruiting · Phase 2 · Interventional · 50 enrolled · National Cancer Institute (NCI)NCT06064097updated 2026-06-12
- A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and ToxicityRecruiting · Phase 2 · Interventional · 60 enrolled · National Cancer Institute (NCI)NCT06406465updated 2026-06-12
- Effects of Dietary Nitrate in Women With Secondary AmenorrheaTerminated · Interventional · 3 enrolled · Indiana UniversityNCT07019129updated 2026-06-12
Frequently asked questions
- How does Nitrogen work?
- Mechanism-of-action class: Unknown Cellular or Molecular Interaction.
- What class of drug is Nitrogen?
- Nitrogen is classified as Medical gases, Unknown Cellular or Molecular Interaction, Unknown Physiological Effect.
- What are the brand names for Nitrogen?
- Nitrogen is marketed under brand names including INOmax, Noxivent, Ulspira.
Note. Data for
nitrogen is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.