Octopamine
Adrenergic and dopaminergic agentsAdrenergic alpha-AgonistsVasoconstrictionUS-FDASourced from openFDA
GET
/api/v1/drug/octopamineMechanism of action
Sourced from openFDAMechanism-of-action class: Adrenergic alpha-Agonists.
Indications
Sourced from openFDA- For the temporary relief of bloating, gas, indigestion, occasional headache, or lethargy due to sensitivity to phenolic compounds found in foods or other products.*ICD-10: R51.9
Dosage & administration
Sourced from openFDADIRECTIONS Place drops under tongue 30 minutes before/after meals. Adults and children 12 years and over: Take 10 drops up to 3 times per day. Consult a physician for use in children under 12 years of age.
Warnings & precautions
Sourced from openFDAIn case of overdose, get medical help or contact a poison control center right away. Keep out of the reach of children. If pregnant or breastfeeding, ask a healthcare professional before use.
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
1 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Asthenia1100%
- 2Brain Operation1100%
- 3Cerebral Haemorrhage1100%
- 4Diaphragmatic Disorder1100%
- 5Drug Interaction1100%
- 6Headache1100%
- 7Hyperhidrosis1100%
- 8Hyperreflexia1100%
- 9Hypertensive Crisis1100%
- 10Labile Hypertension1100%
- 11Lethargy1100%
- 12Nausea1100%
- 13Neurological Decompensation1100%
- 14Serotonin Syndrome1100%
- 15Vomiting1100%
Literature
Recent PubMed references pinned to Octopamine as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- A positive feedback loop between sensory and octopaminergic neurons underlies nociceptive plasticity in Drosophila larvae.PLoS genetics · 2026 · Boivin JC, Zhao YQ, Zhu J, et al.PMID 42048383DOI 10.1371/journal.pgen.1012122
- Cross-Platform Neurotransmitter & Alias Ambiguity for OA-AL2b1 and OA-AL2b2 Neurons in Drosophila melanogaster.Neuroinformatics · 2026 · Olivera RAPMID 42043632DOI 10.1007/s12021-026-09783-4
- Selective octopaminergic tuning of mushroom body circuits during memory formation.Proceedings of the National Academy of Sciences of the United States of America · 2026 · Franke US, Großjohann A, Aurich S, et al.PMID 41980099DOI 10.1073/pnas.2517403123
- Octopamine signaling from clock neurons plays dual roles in Drosophila long-term memory.PLoS genetics · 2026 · Kurata Y, Yoshii T, Sakai T, et al.PMID 41701772DOI 10.1371/journal.pgen.1012045
- Octopamine and tyramine dynamics predict learning rate phenotypes during associative conditioning in honey bees.Science advances · 2026 · Sands LP, Lei H, Batten SR, et al.PMID 41671354DOI 10.1126/sciadv.aea8433
- Octopamine modulates the innate immune response in Drosophila melanogaster.Frontiers in immunology · 2025 · Uliczka K, Papenmeier S, Höschler B, et al.PMID 41583465DOI 10.3389/fimmu.2025.1720126
- Machine Learning for Separating Dopamine and Octopamine Electrochemical Signals in Drosophila.Analytical chemistry · 2026 · Park C, Venton BJPMID 41480932DOI 10.1021/acs.analchem.5c04155
- Hungry for Knowledge: Octopamine Signaling Regulates Hunger-Enhanced Olfactory Learning.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026 · Zhao H, Shi G, Qin R, et al.PMID 41392936DOI 10.1002/advs.202513842
Frequently asked questions
- How does Octopamine work?
- Mechanism-of-action class: Adrenergic alpha-Agonists.
- What is Octopamine used for?
- According to FDA labeling, Octopamine carries indications including: For the temporary relief of bloating, gas, indigestion, occasional headache, or lethargy due to sensitivity to phenolic compounds found in foods or other products.*. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Octopamine?
- Octopamine is classified as Adrenergic and dopaminergic agents, Adrenergic alpha-Agonists, Vasoconstriction.
Note. Data for
octopamine is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.