Tubocurarine
GET
/api/v1/drug/tubocurarineMechanism of action
Sourced from openFDAMechanism-of-action classes: Cholinergic Neuromuscular Nicotinic Antagonists; Competitive Cholinergic Nicotinic Antagonists.
Cholinergic Neuromuscular NicotinicCompetitive Cholinergic Nicotinic
Indications
Sourced from openFDA- Relieves tingling pain in the limbs due to overuse * Uses: See symptoms on front panel.
Dosage & administration
Sourced from openFDAAdults and children: At the onset of symptoms, dissolve 5 pellets under the tongue 3 times a day until symptoms are relieved or as directed by a doctor.
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
10 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Drug Dependence220%
- 2Drug Hypersensitivity220%
- 3Acidosis110%
- 4Anaesthetic Complication110%
- 5Anaphylactic Shock110%
- 6Arrhythmia110%
- 7Bipolar I Disorder110%
- 8Blood Glucose Abnormal110%
- 9Blood Pressure Abnormal110%
- 10Body Temperature Increased110%
- 11Brain Oedema110%
- 12Cardiac Arrest110%
- 13Cyanosis110%
- 14Device Malfunction110%
- 15Diabetic Ketoacidosis110%
Literature
Recent PubMed references pinned to Tubocurarine as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- LC and LC-MS/MS studies for identification and characterization of degradation products of d-tubocurarine chloride.Journal of pharmaceutical and biomedical analysis · 2023 · Grover P, Maheshwari S, Nagarajan K, et al.PMID 36343537DOI 10.1016/j.jpba.2022.115119
- Repositioning of tubocurarine as analgesic and anti-inflammatory agent: Exploring beyond myorelaxant activity.Biochemical pharmacology · 2022 · Patel S, Shukla J, Jain S, et al.PMID 36113566DOI 10.1016/j.bcp.2022.115248
- Curare alkaloids from Matis Dart Poison: Comparison with d-tubocurarine in interactions with nicotinic, 5-HT3 serotonin and GABAA receptors.PloS one · 2019 · Spirova EN, Ivanov IA, Kasheverov IE, et al.PMID 30608952DOI 10.1371/journal.pone.0210182
- A Modular Access to (±)-Tubocurine and (±)-Curine - Formal Total Synthesis of Tubocurarine.The Journal of organic chemistry · 2017 · Otto N, Ferenc D, Opatz T, et al.PMID 27997804DOI 10.1021/acs.joc.6b02647
- Curare Alkaloids: Constituents of a Matis Dart Poison.Journal of natural products · 2015 · Malca Garcia GR, Hennig L, Shelukhina IV, et al.PMID 26496427DOI 10.1021/acs.jnatprod.5b00457
- "Neostigmine-resistant curarization".Middle East journal of anaesthesiology · 2013 · Baraka APMID 24180159
- Syntheses of strychnine, norfluorocurarine, dehydrodesacetylretuline, and valparicine enabled by intramolecular cycloadditions of Zincke aldehydes.The Journal of organic chemistry · 2012 · Martin DB, Nguyen LQ, Vanderwal CD, et al.PMID 22168233DOI 10.1021/jo2020246
- From d-tubocurarine to sugammadex: the contributions of T. Cecil Gray to modern anaesthetic practice.British journal of anaesthesia · 2011 · Shafer SLPMID 21613280DOI 10.1093/bja/aer117
Frequently asked questions
- How does Tubocurarine work?
- Mechanism-of-action classes: Cholinergic Neuromuscular Nicotinic Antagonists; Competitive Cholinergic Nicotinic Antagonists.
- What is Tubocurarine used for?
- According to FDA labeling, Tubocurarine carries indications including: Relieves tingling pain in the limbs due to overuse * Uses: See symptoms on front panel.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Tubocurarine?
- Tubocurarine is classified as Curare alkaloids, Cholinergic Neuromuscular Nicotinic Antagonists, Competitive Cholinergic Nicotinic Antagonists, Decreased Striated Muscle Contraction.
Note. Data for
tubocurarine is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.