Akathisia
14 drugs6,895 FAERS reportsMedDRA PT
GET
/api/v1/reaction/akathisiaReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D011595
A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.
Source: U.S. National Library of Medicine — MeSH (Psychomotor Agitation)
Drugs reporting Akathisia (14)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Trifluoperazine4134%
- 2Thioridazine59.4%
- 3Perphenazine1869.0%
- 4Fluphenazine387.2%
- 5Brexpiprazole8645.4%
- 6Amisulpride3055.2%
- 7Asenapine4164.8%
- 8Cariprazine4064.6%
- 9Loxapine1554.2%
- 10Lurasidone5692.8%
- 11Thiothixene62.8%
- 12Haloperidol6982.6%
- 13Aripiprazole3,0542.5%
- 14Lumateperone1522.4%
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
- Tardive Dyskinesia7 shared · 0.35
- Dystonia5 shared · 0.25
- Antipsychotic Drug Level Below Therapeutic3 shared · 0.21
- Obsessive-compulsive Disorder3 shared · 0.21
- Neuroleptic Malignant Syndrome4 shared · 0.20
- Disinhibition3 shared · 0.20
- Mania3 shared · 0.20
- Therapeutic Product Effect Variable3 shared · 0.20
- Increased Appetite3 shared · 0.19
- Extrapyramidal Disorder4 shared · 0.18
Literature
Recent PubMed references pinned to Psychomotor Agitation as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Memantine as an Adjunctive Treatment for Residual Anxiety and Agitation in Early Parkinson's Disease With Depression: A Case Report.Neuropsychopharmacology reports · 2026 · Haga T, Mori Y, Matsuda N, et al.PMID 42130257DOI 10.1002/npr2.70129
- Agitation Severity and Psychotropic Prescription in Acute Patients With Delirium Superimposed on Dementia.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2026 · Falciola J, Herrmann FR, Graf CE, et al.PMID 42047479DOI 10.1111/psyg.70171
- Pediatric Emergency Agitation Care Enhancement: Protocol for a Prospective Mixed Methods Study.JMIR research protocols · 2026 · Klein L, Pomerantz W, Pestian T, et al.PMID 42013213DOI 10.2196/92452
- Pharmacotherapeutic landscape for the management of agitation associated with Alzheimer's disease.Expert opinion on pharmacotherapy · 2026 · Jain S, Tunc EB, Grossberg GT, et al.PMID 42013076DOI 10.1080/14656566.2026.2662949
- Prevalence, risk factors, and prognosis of the need for physical and chemical restraint in older patients attending emergency departments. EDEN-50.The American journal of emergency medicine · 2026 · Llorens P, Cano S, Espinosa B, et al.PMID 42000676DOI 10.1016/j.ajem.2026.03.029
- Akathisia Induced by Metoclopramide in a Pregnant Woman With Nausea and Vomiting: A Case Report.Neuropsychopharmacology reports · 2026 · Nakamura R, Noto K, Shirata T, et al.PMID 41979046DOI 10.1002/npr2.70122
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.