Mania
4 drugs2,167 FAERS reportsMedDRA PT
GET
/api/v1/reaction/maniaReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D000087122
A state of elevated excitement with over-activity sometimes accompanied with psychotic symptoms (e.g., PSYCHOMOTOR AGITATION, inflated SELF ESTEEM and flight of ideas). It is often associated with mental disorders (e.g., CYCLOTHYMIC DISORDER; and BIPOLAR DISEASES).
Drugs reporting Mania (4)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Lumateperone2544.1%
- 2Lithium1,1792.8%
- 3Lurasidone5692.8%
- 4Cariprazine1651.9%
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
Literature
Recent PubMed references pinned to Mania as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Manic and hypomanic states in cancer patients: A systematic review.Palliative & supportive care · 2026 · Osawa K, Fujisawa DPMID 42100881DOI 10.1017/S1478951526102466
- Peripheral orexin system alterations in acute bipolar mania: Associations with clinical features and diagnostic performance.Journal of affective disorders · 2026 · Erdogan EC, Ugurlu M, Kabadayi Sahin E, et al.PMID 42096890DOI 10.1016/j.jad.2026.121921
- Polarisation of brain dynamics in mania and depression.Dialogues in clinical neuroscience · 2026 · Martino M, Magioncalda P, Conio B, et al.PMID 42052967DOI 10.1080/19585969.2026.2663032
- Mood switching in 1629 antidepressant-treated bipolar disorder patients.Journal of affective disorders · 2026 · Miola A, Tondo L, Pinna M, et al.PMID 42035800DOI 10.1016/j.jad.2026.121849
- Characterization of altered brain functional activity in patients with hypomania.Journal of psychiatric research · 2026 · Liu Y, Ji X, Xu P, et al.PMID 41894926DOI 10.1016/j.jpsychires.2026.03.026
- When Mania Outruns the Law: Managing Risk in the Liminal Zone.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2026 · Costa-Dookhan KA, Lustig APMID 41869871DOI 10.1177/07067437261433736
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.