Drug Resistance
67 drugs18,271 FAERS reportsMedDRA PT
GET
/api/v1/reaction/drug-resistanceReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D004351
Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
Source: U.S. National Library of Medicine — MeSH (Drug Resistance)
Drugs reporting Drug Resistance (67)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Adefovir27522%
- 2Tecovirimat1918%
- 3Gefitinib1,24914%
- 4Foscarnet50113%
- 5Streptomycin14513%
- 6Nevirapine1,02812%
- 7Tafenoquine811%
- 8Piperonyl Butoxide111%
- 9Pyrethrum Extract111%
- 10Cidofovir14811%
- 11Cefiderocol309.9%
- 12Peramivir159.7%
- 13Interleukin-1219.1%
- 14Brincidofovir128.8%
- 15Gentian Violet47.8%
- 16Rimantadine27.7%
- 17Maribavir1767.6%
- 18Avibactam117.0%
- 19Ensartinib26.9%
- 20Ganciclovir7206.7%
- 21Efavirenz7356.6%
- 22Cefoxitin896.5%
- 23Etravirine2585.9%
- 24Rifabutin1605.6%
- 25Cycloserine1175.3%
- 26Fosamprenavir64.6%
- 27Lamivudine2,0404.3%
- 28Doravirine434.2%
- 29Vaborbactam24.1%
- 30Zidovudine7964.0%
- 31Hepatitis B Immune Globulin23.9%
- 32Pyrazinamide3533.8%
- 33Erlotinib4733.8%
- 34Anidulafungin583.7%
- 35Valganciclovir6583.6%
- 36Osimertinib1,0823.6%
- 37Tigecycline2123.5%
- 38Entecavir4033.5%
- 39Maraviroc793.5%
- 40Amikacin6163.4%
- 41Pentobarbital33.3%
- 42Rifampin4533.2%
- 43Letermovir953.2%
- 44Griseofulvin93.2%
- 45Ceftolozane303.1%
- 46Artemether63.1%
- 47Lumefantrine63.1%
- 48Rufinamide773.0%
- 49Imatinib1,2092.9%
- 50Isoniazid4542.9%
- 51Dactinomycin612.8%
- 52Miltefosine102.7%
- 53Flucytosine352.6%
- 54Linezolid7462.6%
- 55Rezafungin22.6%
- 56Oxacillin282.5%
- 57Meropenem7902.5%
- 58Ceftazidime1822.4%
- 59Terbinafine2042.4%
- 60Relebactam22.2%
- 61Larotrectinib192.2%
- 62Caspofungin1002.2%
- 63Eptifibatide152.0%
- 64Voriconazole5791.9%
- 65Bivalirudin171.8%
- 66Pretomanid111.7%
- 67Dasatinib5981.6%
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
- Pathogen Resistance21 shared · 0.29
- Drug Reaction With Eosinophilia And Systemic Symptoms12 shared · 0.14
- Treatment Failure16 shared · 0.12
- Viral Mutation Identified8 shared · 0.12
- Renal Impairment14 shared · 0.11
- Respiratory Failure16 shared · 0.11
- Septic Shock11 shared · 0.10
- Pancytopenia15 shared · 0.10
- Multiple Organ Dysfunction Syndrome11 shared · 0.10
- Virologic Failure7 shared · 0.09
Literature
Recent PubMed references pinned to Drug Resistance as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Joint effects and dynamic trajectories of metabolic insulin resistance and systemic inflammation in the risk of renal cell carcinoma: a UK Biobank cohort analysis.World journal of urology · 2026 · Chen S, Jiang F, Wang J, et al.PMID 42207184DOI 10.1007/s00345-026-06487-x
- Emergence and dissemination of extensively drug-resistant ST307 Klebsiella pneumoniae in China.Microbial genomics · 2026 · Han W, Yuan X, Yang C, et al.PMID 42207167DOI 10.1099/mgen.0.001718
- In silico identification of isosilybin a targeting squalene epoxidase as an antifungal adjuvant with in vitro validation against azole-resistant Candida and emerging yeasts.Frontiers in cellular and infection microbiology · 2026 · Mundhe AK, Rajkumari RPMID 42205484DOI 10.3389/fcimb.2026.1774455
- Association between single-point insulin sensitivity estimator and three-vessel coronary disease: a cross-sectional study.Frontiers in endocrinology · 2026 · Yang W, Dai G, Quan N, et al.PMID 42205266DOI 10.3389/fendo.2026.1838548
- Lysosome-directed targeted protein degradation technologies for overcoming cancer drug resistance: mechanisms, design principles, and therapeutic opportunities.Drug delivery · 2026 · Mao H, Zhang Y, Liu M, et al.PMID 42204757DOI 10.1080/10717544.2026.2679844
- Enzalutamide Enhanced Honokiol-induced Apoptotic Insults to Drug-resistant Glioblastoma Cells via an Intrinsic Bak-mitochondrion-caspase Cascade Mechanism.Anticancer research · 2026 · Chen CY, Chen JT, Liu SH, et al.PMID 42203314DOI 10.21873/anticanres.18185
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.