Hot Flush
45 drugs46,505 FAERS reportsMedDRA PT
GET
/api/v1/reaction/hot-flushReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D019584
A sudden, temporary sensation of heat predominantly experienced by some women during MENOPAUSE. (Random House Unabridged Dictionary, 2d ed)
Source: U.S. National Library of Medicine — MeSH (Hot Flashes)
Drugs reporting Hot Flush (45)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Relugolix7,29630%
- 2Allylthiourea125%
- 3Prussian Blue Insoluble125%
- 4Ospemifene37214%
- 5Imlunestrant313%
- 6Leuprolide9,55712%
- 7Bexagliflozin312%
- 8Elagolix50112%
- 9Darolutamide58311%
- 10Bazedoxifene788.4%
- 11Oxyquinoline37.9%
- 12Fenbendazole77.9%
- 13Gallium337.8%
- 14Gozetotide337.8%
- 15Apalutamide8467.5%
- 16Oteseconazole27.4%
- 17Nonoxynol-917.1%
- 18Nilutamide56.8%
- 19Enzalutamide3,8506.6%
- 20Flutemetamol266.5%
- 21Degarelix3226.3%
- 22Elinzanetant66.2%
- 23Fezolinetant965.0%
- 24Nirogacestat344.3%
- 25Diroximel Fumarate4624.0%
- 26Anastrozole1,4133.9%
- 27Goserelin5143.9%
- 28Abiraterone1,4653.6%
- 29Tamoxifen1983.5%
- 30Triptorelin1933.4%
- 31Monomethyl Fumarate313.4%
- 32Curcumin43.4%
- 33Zinc Picolinate43.4%
- 34Apple Cider Vinegar43.4%
- 35Cider Vinegar43.4%
- 36Nafarelin93.3%
- 37Apple Cider43.3%
- 38Acetate13,1863.2%
- 39Norethindrone5603.1%
- 40Elacestrant1912.7%
- 41Flotufolastat12.6%
- 42Raloxifene3882.4%
- 43Bremelanotide202.3%
- 44Estrogens1,5602.2%
- 45Dimethyl Fumarate2,6352.2%
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
- Prostatic Specific Antigen Increased9 shared · 0.17
- Infusion Site Erythema5 shared · 0.11
- Arthritis6 shared · 0.10
- Night Sweats4 shared · 0.09
- Infusion Site Pain5 shared · 0.08
- Illness7 shared · 0.07
- Metastases To Bone4 shared · 0.07
- Breast Cancer4 shared · 0.07
- Vaginal Haemorrhage4 shared · 0.07
- Positron Emission Tomogram Abnormal3 shared · 0.07
Literature
Recent PubMed references pinned to Hot Flashes as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Physical activity moderates the relationship between hot flashes and arterial wave reflection in perimenopausal females.Physiological reports · 2026 · Tha Ra Wun T, Brunzelle JS, Murphy L, et al.PMID 42169447DOI 10.14814/phy2.70918
- A systematic review of heart rate variability and menopausal vasomotor symptoms.Physiological reports · 2026 · Hira R, Uppal J, Deol P, et al.PMID 42121335DOI 10.14814/phy2.70907
- Estetrol (E4) for the treatment of moderate to severe vasomotor symptoms in postmenopausal women - Efficacy and safety results from the phase 3 E4COMFORT I multicenter, placebo-controlled study.Maturitas · 2026 · Simoncini T, Bouchard C, Cloes M, et al.PMID 42068869DOI 10.1016/j.maturitas.2026.108965
- Prevalence of vasomotor symptoms and the associated risk factors: the "Mi Menopausia" app study.Maturitas · 2026 · Coronado PJ, Mendoza N, González SP, et al.PMID 42066667DOI 10.1016/j.maturitas.2026.108958
- The effect of acupuncture on hot flashes and sleep disturbances in women with breast cancer receiving endocrine therapy: a pre-post quasi-interventional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026 · Amato C, Iovino P, Becorpi A, et al.PMID 41998196DOI 10.1007/s00520-026-10680-4
- The Role of New Nonhormone Medications in Managing Vasomotor Symptoms Among Individuals With Cancer.Clinical journal of oncology nursing · 2026 · Burbage DPMID 41949347DOI 10.1188/26.CJON.107-111
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.