Gastrooesophageal Reflux Disease

DefinitionNLM MeSH D005764

Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.

Source: U.S. National Library of Medicine — MeSH (Gastroesophageal Reflux)

Drugs reporting Gastrooesophageal Reflux Disease (47)

Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.

1. 1Policresulen1100%
2. 2Cholecalciferol44214%
3. 3Pyrilamine5213%
4. 4Levomilnacipran1759.3%
5. 5Bexagliflozin28.0%
6. 6Magnesium Citrate4627.9%
7. 7Tipranavir1017.3%
8. 8Botulinum Toxin Type A8497.1%
9. 9Asiatic Acid16.7%
10. 10Olmesartan2,5445.9%
11. 11Ciclesonide7675.7%
12. 12Aclidinium3545.6%
13. 13Bismuth Subsalicylate3125.5%
14. 14Iodoquinol25.3%
15. 15Esomeprazole11,9615.1%
16. 16Pyridoxine2375.1%
17. 17Simethicone4025.0%
18. 18Magnesium Hydroxide7804.2%
19. 19Magnesium Carbonate3364.2%
20. 20Dexbrompheniramine104.2%
21. 21Liothyronine3524.1%
22. 22Vitamin A2854.1%
23. 23Cimetidine3754.0%
24. 24Calcium Carbonate2,8003.9%
25. 25Phosphorus3733.8%
26. 26Nizatidine563.7%
27. 27Tretinoin3203.7%
28. 28Oxaprozin323.6%
29. 29Vonoprazan2393.5%
30. 30Dexlansoprazole1,4413.5%
31. 31Aluminum Hydroxide2683.4%
32. 32Dextran553.2%
33. 33Aluminum2783.1%
34. 34Sacrosidase53.0%
35. 35Mometasone1,8622.9%
36. 36Diflorasone52.7%
37. 37Cobaltous Chloride12.7%
38. 38Exametazime12.6%
39. 39Cholic Acid102.5%
40. 40Avutometinib132.5%
41. 41Defactinib132.5%
42. 42Magnesium19,1452.4%
43. 43Eliglustat352.3%
44. 44Xanomeline382.2%
45. 45Hyaluronate172.2%
46. 46Zavegepant121.5%
47. 47Oxymorphone940.8%

Related reactions

Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.

• End Stage Renal Disease7 shared · 0.09
• Renal Injury5 shared · 0.08
• Dyspepsia7 shared · 0.07
• Chronic Kidney Disease14 shared · 0.07
• Abdominal Pain Upper22 shared · 0.06
• Hypoaesthesia6 shared · 0.05
• Asthma6 shared · 0.05
• Throat Irritation3 shared · 0.05
• Taste Disorder3 shared · 0.05
• Renal Failure14 shared · 0.05

Literature

Recent PubMed references pinned to Gastroesophageal Reflux as a MeSH major topic. About the reaction term itself — not about any specific drug.

• Intraoperative gastroesophageal reflux in dogs undergoing mastectomy under opioid-based protocols: a preliminary endoscopic study.
  Veterinary research communications · 2026 · Dos P, Ribas S, Gurgel HJ, et al.
  PMID 42201443DOI 10.1007/s11259-026-11290-5
• Laryngopharyngeal Symptoms and Laryngopharyngeal Reflux Disease: Diagnostic Testing and Clinical Approach Based on the San Diego Consensus.
  Neurogastroenterology and motility · 2026 · O'Rourke A, Sweis R, Jette M, et al.
  PMID 42178700DOI 10.1111/nmo.70351
• Timeline for reinitiation of antireflux medication post-surgical or endoscopic antireflux procedures.
  Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2026 · Simadibrata DM, Fass R
  PMID 42172098DOI 10.1093/dote/doag043
• Elements Affecting Quality of Life in Individuals With Gastroesophagel Reflux Disease.
  JSLS : Journal of the Society of Laparoendoscopic Surgeons · 2026 · Kong L, Zheng Y, Cui Y, et al.
  PMID 42164550DOI 10.4293/JSLS.2025.00091
• Substance Use Disorders Are Associated With Increased Long-Term Risks of Gastroesophageal Reflux Disease Phenotypes: A Global Propensity-Matched Cohort Study.
  Neurogastroenterology and motility · 2026 · Sun Y, Veccia D, Liu B, et al.
  PMID 42163038DOI 10.1111/nmo.70329
• Gastrostomy plus fundoplication or gastro-jejunal tube or gastrostomy alone for treating or preventing gastro-esophageal reflux in children and adolescents with neurological impairment.
  The Cochrane database of systematic reviews · 2026 · Flores JC, Campos JM, Gana JC, et al.
  PMID 42159156DOI 10.1002/14651858.CD015007.pub2